Population dynamics and genetic connectivity in recent chimpanzee history

Knowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we produced the first non-invasive geolocalized catalog of genomic diversity by capturing chromosome 21 from 828 non-invasive...

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Autores: Fontseré Alemany, Clàudia, Kuhlwilm, Martin, Morcillo Suárez, Carlos, Alvarez-Estape, Marina, Lester, Jack de, Gratton, Paolo, Schmidt, Joshua M., Diéguez, Paula, Aebischer, Thierry, Álvarez-Varona, Paula, Agbor, Anthony, Angedakin, Samuel, Assumang, Alfred K., Ayimisin, Emmanuel A., Bailey, Emma, Barubiyo, Donatienne, Bessone, Mattia, Carretero-Alonso, Andrea, Chancellor, Rebecca, Cohen, Heather, Danquah, Emmanuel, Deschner, Tobias, Dunn, Andrew, Dupain, Jef, Egbe, Villard E., Feliu, Olga, Goedmakers, Annemarie, Granjon, Anne-Céline, Head, Josephine, Hedwig, Daniela, Hermans, Veerle, Hernández Aguilar, Adriana, Imong, Inaoyom, Jones, Sorrel, Junker, Jessica, Kadam, Parag, Kaiser, Mike, Kambere, Mbangi, Kambale, Magloire V., Kalan, Ammie K., Kienast, Ivonne, Kujirakwinja, Deo, Langergraber, Kevin, Lapuente, Juan, Larson, Bradley, Laudisoit, Anne, Lee, Kevin, Llana, Manuel, Llorente Espino, Miquel, Marrocoli, Sergio, Morgan, David, Mulindahabi, Felix, Murai, Mizuki, Neil, Emily, Nicholl, Sonia, Nixon, Stuart, Normand, Emma, Orbell, Chris, Ormsby, Lucy J., Pacheco, Liliana, Piel, Alex, Riera, Laura, Robbins, Martha M., Rundus, Aaron, Sanz, Crickette, Sciaky, Lilah, Sommer, Volker, Stewart, Fiona A., Tagg, Nikki, Tédonzong, Luc Roscelin, Ton, Els, Schijndel, Joost van, Vergnes, Virginie, Wessling, Erin G., Willie, Jacob, Wittig, Roman M., Yuh, Yisa G., Yurkiw, Kyle, Zuberbuehler, Klaus, Hecht, Jochen, Vigilant, Linda, Boesch, Christophe, Andrés, Aida M., Hughes, David A., Kühl, Hjalmar S., Lizano, Esther, Arandjelovic, Mimi, Marques-Bonet, Tomas
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2022
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/21766
Acesso em linha:http://hdl.handle.net/10256/21766
Access Level:Acceso aberto
Palavra-chave:Ximpanzés
Chimpanzees
Genòmica
Genomics
Genètica de poblacions
Population genetics
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oai_identifier_str oai:recercat.cat:10256/21766
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dc.title.none.fl_str_mv Population dynamics and genetic connectivity in recent chimpanzee history
title Population dynamics and genetic connectivity in recent chimpanzee history
spellingShingle Population dynamics and genetic connectivity in recent chimpanzee history
Fontseré Alemany, Clàudia
Ximpanzés
Chimpanzees
Genòmica
Genomics
Genètica de poblacions
Population genetics
title_short Population dynamics and genetic connectivity in recent chimpanzee history
title_full Population dynamics and genetic connectivity in recent chimpanzee history
title_fullStr Population dynamics and genetic connectivity in recent chimpanzee history
title_full_unstemmed Population dynamics and genetic connectivity in recent chimpanzee history
title_sort Population dynamics and genetic connectivity in recent chimpanzee history
dc.creator.none.fl_str_mv Fontseré Alemany, Clàudia
Kuhlwilm, Martin
Morcillo Suárez, Carlos
Alvarez-Estape, Marina
Lester, Jack de
Gratton, Paolo
Schmidt, Joshua M.
Diéguez, Paula
Aebischer, Thierry
Álvarez-Varona, Paula
Agbor, Anthony
Angedakin, Samuel
Assumang, Alfred K.
Ayimisin, Emmanuel A.
Bailey, Emma
Barubiyo, Donatienne
Bessone, Mattia
Carretero-Alonso, Andrea
Chancellor, Rebecca
Cohen, Heather
Danquah, Emmanuel
Deschner, Tobias
Dunn, Andrew
Dupain, Jef
Egbe, Villard E.
Feliu, Olga
Goedmakers, Annemarie
Granjon, Anne-Céline
Head, Josephine
Hedwig, Daniela
Hermans, Veerle
Hernández Aguilar, Adriana
Imong, Inaoyom
Jones, Sorrel
Junker, Jessica
Kadam, Parag
Kaiser, Mike
Kambere, Mbangi
Kambale, Magloire V.
Kalan, Ammie K.
Kienast, Ivonne
Kujirakwinja, Deo
Langergraber, Kevin
Lapuente, Juan
Larson, Bradley
Laudisoit, Anne
Lee, Kevin
Llana, Manuel
Llorente Espino, Miquel
Marrocoli, Sergio
Morgan, David
Mulindahabi, Felix
Murai, Mizuki
Neil, Emily
Nicholl, Sonia
Nixon, Stuart
Normand, Emma
Orbell, Chris
Ormsby, Lucy J.
Pacheco, Liliana
Piel, Alex
Riera, Laura
Robbins, Martha M.
Rundus, Aaron
Sanz, Crickette
Sciaky, Lilah
Sommer, Volker
Stewart, Fiona A.
Tagg, Nikki
Tédonzong, Luc Roscelin
Ton, Els
Schijndel, Joost van
Vergnes, Virginie
Wessling, Erin G.
Willie, Jacob
Wittig, Roman M.
Yuh, Yisa G.
Yurkiw, Kyle
Zuberbuehler, Klaus
Hecht, Jochen
Vigilant, Linda
Boesch, Christophe
Andrés, Aida M.
Hughes, David A.
Kühl, Hjalmar S.
Lizano, Esther
Arandjelovic, Mimi
Marques-Bonet, Tomas
author Fontseré Alemany, Clàudia
author_facet Fontseré Alemany, Clàudia
Kuhlwilm, Martin
Morcillo Suárez, Carlos
Alvarez-Estape, Marina
Lester, Jack de
Gratton, Paolo
Schmidt, Joshua M.
Diéguez, Paula
Aebischer, Thierry
Álvarez-Varona, Paula
Agbor, Anthony
Angedakin, Samuel
Assumang, Alfred K.
Ayimisin, Emmanuel A.
Bailey, Emma
Barubiyo, Donatienne
Bessone, Mattia
Carretero-Alonso, Andrea
Chancellor, Rebecca
Cohen, Heather
Danquah, Emmanuel
Deschner, Tobias
Dunn, Andrew
Dupain, Jef
Egbe, Villard E.
Feliu, Olga
Goedmakers, Annemarie
Granjon, Anne-Céline
Head, Josephine
Hedwig, Daniela
Hermans, Veerle
Hernández Aguilar, Adriana
Imong, Inaoyom
Jones, Sorrel
Junker, Jessica
Kadam, Parag
Kaiser, Mike
Kambere, Mbangi
Kambale, Magloire V.
Kalan, Ammie K.
Kienast, Ivonne
Kujirakwinja, Deo
Langergraber, Kevin
Lapuente, Juan
Larson, Bradley
Laudisoit, Anne
Lee, Kevin
Llana, Manuel
Llorente Espino, Miquel
Marrocoli, Sergio
Morgan, David
Mulindahabi, Felix
Murai, Mizuki
Neil, Emily
Nicholl, Sonia
Nixon, Stuart
Normand, Emma
Orbell, Chris
Ormsby, Lucy J.
Pacheco, Liliana
Piel, Alex
Riera, Laura
Robbins, Martha M.
Rundus, Aaron
Sanz, Crickette
Sciaky, Lilah
Sommer, Volker
Stewart, Fiona A.
Tagg, Nikki
Tédonzong, Luc Roscelin
Ton, Els
Schijndel, Joost van
Vergnes, Virginie
Wessling, Erin G.
Willie, Jacob
Wittig, Roman M.
Yuh, Yisa G.
Yurkiw, Kyle
Zuberbuehler, Klaus
Hecht, Jochen
Vigilant, Linda
Boesch, Christophe
Andrés, Aida M.
Hughes, David A.
Kühl, Hjalmar S.
Lizano, Esther
Arandjelovic, Mimi
Marques-Bonet, Tomas
author_role author
author2 Kuhlwilm, Martin
Morcillo Suárez, Carlos
Alvarez-Estape, Marina
Lester, Jack de
Gratton, Paolo
Schmidt, Joshua M.
Diéguez, Paula
Aebischer, Thierry
Álvarez-Varona, Paula
Agbor, Anthony
Angedakin, Samuel
Assumang, Alfred K.
Ayimisin, Emmanuel A.
Bailey, Emma
Barubiyo, Donatienne
Bessone, Mattia
Carretero-Alonso, Andrea
Chancellor, Rebecca
Cohen, Heather
Danquah, Emmanuel
Deschner, Tobias
Dunn, Andrew
Dupain, Jef
Egbe, Villard E.
Feliu, Olga
Goedmakers, Annemarie
Granjon, Anne-Céline
Head, Josephine
Hedwig, Daniela
Hermans, Veerle
Hernández Aguilar, Adriana
Imong, Inaoyom
Jones, Sorrel
Junker, Jessica
Kadam, Parag
Kaiser, Mike
Kambere, Mbangi
Kambale, Magloire V.
Kalan, Ammie K.
Kienast, Ivonne
Kujirakwinja, Deo
Langergraber, Kevin
Lapuente, Juan
Larson, Bradley
Laudisoit, Anne
Lee, Kevin
Llana, Manuel
Llorente Espino, Miquel
Marrocoli, Sergio
Morgan, David
Mulindahabi, Felix
Murai, Mizuki
Neil, Emily
Nicholl, Sonia
Nixon, Stuart
Normand, Emma
Orbell, Chris
Ormsby, Lucy J.
Pacheco, Liliana
Piel, Alex
Riera, Laura
Robbins, Martha M.
Rundus, Aaron
Sanz, Crickette
Sciaky, Lilah
Sommer, Volker
Stewart, Fiona A.
Tagg, Nikki
Tédonzong, Luc Roscelin
Ton, Els
Schijndel, Joost van
Vergnes, Virginie
Wessling, Erin G.
Willie, Jacob
Wittig, Roman M.
Yuh, Yisa G.
Yurkiw, Kyle
Zuberbuehler, Klaus
Hecht, Jochen
Vigilant, Linda
Boesch, Christophe
Andrés, Aida M.
Hughes, David A.
Kühl, Hjalmar S.
Lizano, Esther
Arandjelovic, Mimi
Marques-Bonet, Tomas
author2_role author
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dc.subject.none.fl_str_mv Ximpanzés
Chimpanzees
Genòmica
Genomics
Genètica de poblacions
Population genetics
topic Ximpanzés
Chimpanzees
Genòmica
Genomics
Genètica de poblacions
Population genetics
description Knowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we produced the first non-invasive geolocalized catalog of genomic diversity by capturing chromosome 21 from 828 non-invasive samples collected at 48 sampling sites across Africa. The four recognized subspecies show clear genetic differentiation correlating with known barriers, while previously undescribed genetic exchange suggests that these have been permeable on a local scale. We obtained a detailed reconstruction of population stratification and fine-scale patterns of isolation, migration, and connectivity, including a comprehensive picture of admixture with bonobos (Pan paniscus). Unlike humans, chimpanzees did not experience extended episodes of long-distance migrations, which might have limited cultural transmission. Finally, based on local rare variation, we implement a fine-grained geolocalization approach demonstrating improved precision in determining the origin of confiscated chimpanzees
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer-reviewed
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10256/21766
http://hdl.handle.net/10256/21766
url http://hdl.handle.net/10256/21766
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.xgen.2022.100133
info:eu-repo/semantics/altIdentifier/eissn/2666-979X
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Cell Genomics, 2022, vol. 2, núm. 6, p.100133
Articles publicats (D-PS)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling Population dynamics and genetic connectivity in recent chimpanzee historyFontseré Alemany, ClàudiaKuhlwilm, MartinMorcillo Suárez, CarlosAlvarez-Estape, MarinaLester, Jack deGratton, PaoloSchmidt, Joshua M.Diéguez, PaulaAebischer, ThierryÁlvarez-Varona, PaulaAgbor, AnthonyAngedakin, SamuelAssumang, Alfred K.Ayimisin, Emmanuel A.Bailey, EmmaBarubiyo, DonatienneBessone, MattiaCarretero-Alonso, AndreaChancellor, RebeccaCohen, HeatherDanquah, EmmanuelDeschner, TobiasDunn, AndrewDupain, JefEgbe, Villard E.Feliu, OlgaGoedmakers, AnnemarieGranjon, Anne-CélineHead, JosephineHedwig, DanielaHermans, VeerleHernández Aguilar, AdrianaImong, InaoyomJones, SorrelJunker, JessicaKadam, ParagKaiser, MikeKambere, MbangiKambale, Magloire V.Kalan, Ammie K.Kienast, IvonneKujirakwinja, DeoLangergraber, KevinLapuente, JuanLarson, BradleyLaudisoit, AnneLee, KevinLlana, ManuelLlorente Espino, MiquelMarrocoli, SergioMorgan, DavidMulindahabi, FelixMurai, MizukiNeil, EmilyNicholl, SoniaNixon, StuartNormand, EmmaOrbell, ChrisOrmsby, Lucy J.Pacheco, LilianaPiel, AlexRiera, LauraRobbins, Martha M.Rundus, AaronSanz, CricketteSciaky, LilahSommer, VolkerStewart, Fiona A.Tagg, NikkiTédonzong, Luc RoscelinTon, ElsSchijndel, Joost vanVergnes, VirginieWessling, Erin G.Willie, JacobWittig, Roman M.Yuh, Yisa G.Yurkiw, KyleZuberbuehler, KlausHecht, JochenVigilant, LindaBoesch, ChristopheAndrés, Aida M.Hughes, David A.Kühl, Hjalmar S.Lizano, EstherArandjelovic, MimiMarques-Bonet, TomasXimpanzésChimpanzeesGenòmicaGenomicsGenètica de poblacionsPopulation geneticsKnowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we produced the first non-invasive geolocalized catalog of genomic diversity by capturing chromosome 21 from 828 non-invasive samples collected at 48 sampling sites across Africa. The four recognized subspecies show clear genetic differentiation correlating with known barriers, while previously undescribed genetic exchange suggests that these have been permeable on a local scale. We obtained a detailed reconstruction of population stratification and fine-scale patterns of isolation, migration, and connectivity, including a comprehensive picture of admixture with bonobos (Pan paniscus). Unlike humans, chimpanzees did not experience extended episodes of long-distance migrations, which might have limited cultural transmission. Finally, based on local rare variation, we implement a fine-grained geolocalization approach demonstrating improved precision in determining the origin of confiscated chimpanzeesFunding: “la Caixa” Foundation doctoral fellowship program LCF/BQ/DE15/10360006 (to C.F.). FPI (Formación de Personal Investigador) PRE2018-083966 from Ministerio de Ciencia, Universidades e Investigación (to M.A.-E.) and CGL2017-82654-P (MINECO/FEDER, UE) (to E.L.). “la Caixa” Foundation (ID 100010434), fellowship code LCF/BQ/PR19/11700002 (to M.K.). Vienna Science and Technology Fund (WWTF) and the City of Vienna project VRG20-001 (to M.K.). The European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 864203) (to T.M.-B.). BFU2017-86471-P (MINECO/FEDER, UE) (to T.M.-B.). “Unidad de Excelencia María de Maeztu”, funded by the AEI (CEX2018-000792-M) (to T.M.-B.). Howard Hughes International Early Career (to T.M.-B.). NIH 1R01HG010898-01A1 (to T.M.-B.). Secretaria d’Universitats i Recerca and CERCA Program del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2017 SGR 880) (to T.M.-B.). UCL’s Wellcome Trust ISSF3 award 204841/Z/16/Z (to A.M.A. and J.M.S.). Generalitat de Catalunya (2017 SGR-1040) (to M. Llorente). Wellcome Trust Investigator Award 202802/Z/16/Z (to D.A.H.). The Pan African Program: The Cultured Chimpanzee (PanAf) is generously funded by the Max Planck Society, the Max Planck Society Innovation Fund, and the Heinz L. Krekeler FoundationElsevier2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer-reviewedapplication/pdfhttp://hdl.handle.net/10256/21766http://hdl.handle.net/10256/21766Cell Genomics, 2022, vol. 2, núm. 6, p.100133Articles publicats (D-PS)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)Inglésinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.xgen.2022.100133info:eu-repo/semantics/altIdentifier/eissn/2666-979XAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10256/217662026-05-29T05:05:01Z
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