Adapt or perish: SARS-CoV-2 antibody escape variants defined by deletions in the Spike N-terminal Domain
In a recent report in Science, McCarthy et al. promptly observed a pattern of recurrent deletions in four discrete regions of the Nterminal Domain (NTD) of the Spike protein, which provide resistance to antibody neutralization, suggesting convergent evolution due to selective pressure and antigenic...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de Navarra |
| Repositorio: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Idioma: | inglés |
| OAI Identifier: | oai:dadun.unav.edu:10171/114911 |
| Acceso en línea: | https://hdl.handle.net/10171/114911 |
| Access Level: | acceso abierto |
| Palabra clave: | SARS-CoV-2 Variants Deletion N-terminal Domain |
| Sumario: | In a recent report in Science, McCarthy et al. promptly observed a pattern of recurrent deletions in four discrete regions of the Nterminal Domain (NTD) of the Spike protein, which provide resistance to antibody neutralization, suggesting convergent evolution due to selective pressure and antigenic drift. |
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