A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia

Background: Significant bleeding during functional endoscopic naso-sinusal surgery (FESS) impairs recognition of anatomical references and may negatively affect surgical outcome. Anaesthesia including clonidine as an adjuntive hypotensive agent may reduce intraoperative bleeding. Methods: A randomis...

Descripción completa

Detalles Bibliográficos
Autores: Cardesin, A, Pontes, C, Rosell, R, Escamilla, Y, Marco, J, Escobar, MJ, Bernal-Sprekelsen, M
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p5643
Acceso en línea:https://i3pt.portalinvestigacion.com/publicaciones/5643
Access Level:acceso abierto
Palabra clave:Functional Endoscopic Sinus Surgery
bleeding
clonidine
blood loss
general anaesthesia
id ES_79398e6f6882e4eba69e9f3fae7eedda
oai_identifier_str oai:i3pt.fundanetsuite.com:p5643
network_acronym_str ES
network_name_str España
repository_id_str
spelling A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesiaCardesin, APontes, CRosell, REscamilla, YMarco, JEscobar, MJBernal-Sprekelsen, MFunctional Endoscopic Sinus Surgerybleedingclonidineblood lossgeneral anaesthesiaBackground: Significant bleeding during functional endoscopic naso-sinusal surgery (FESS) impairs recognition of anatomical references and may negatively affect surgical outcome. Anaesthesia including clonidine as an adjuntive hypotensive agent may reduce intraoperative bleeding. Methods: A randomised comparison of clonidine-based vs remifentanil-based hypotensive anaesthetic regimen was conducted in patients undergoing FESS. The main assessment was the proportion of subjects with Boezaart scores of surgical field bleeding, as blindly assessed from video recordings by a third surgeon not involved in patient care. Results: A total of 47 subjects underwent FESS and were randomised to clonidine or remifentanil. A significantly lower proportion of patients in the clonidine arm had blindly-assessed Boezaart scores higher than 2, with significantly lower mean blind Boezaart scores at 60 minutes and at 120 minutes. Similar findings were reported by the operating surgeon, and when Wormald and VAS scores were used. Objective estimates of bleeding and the duration of surgery and anaesthesia did not differ between groups. Conclusion: The use of clonidine-based controlled hypotensive anaesthesia achieves lower surgical field bleeding during FESS.INT RHINOLOGIC SOC2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://i3pt.portalinvestigacion.com/publicaciones/5643RHINOLOGYISSN: 03000729reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulíinstname:Institut d'Investigació i Innovació Parc Taulí (I3PT)Inglésinfo:eu-repo/semantics/openAccessoai:i3pt.fundanetsuite.com:p56432026-06-21T15:30:37Z
dc.title.none.fl_str_mv A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
title A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
spellingShingle A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
Cardesin, A
Functional Endoscopic Sinus Surgery
bleeding
clonidine
blood loss
general anaesthesia
title_short A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
title_full A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
title_fullStr A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
title_full_unstemmed A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
title_sort A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia
dc.creator.none.fl_str_mv Cardesin, A
Pontes, C
Rosell, R
Escamilla, Y
Marco, J
Escobar, MJ
Bernal-Sprekelsen, M
author Cardesin, A
author_facet Cardesin, A
Pontes, C
Rosell, R
Escamilla, Y
Marco, J
Escobar, MJ
Bernal-Sprekelsen, M
author_role author
author2 Pontes, C
Rosell, R
Escamilla, Y
Marco, J
Escobar, MJ
Bernal-Sprekelsen, M
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Functional Endoscopic Sinus Surgery
bleeding
clonidine
blood loss
general anaesthesia
topic Functional Endoscopic Sinus Surgery
bleeding
clonidine
blood loss
general anaesthesia
description Background: Significant bleeding during functional endoscopic naso-sinusal surgery (FESS) impairs recognition of anatomical references and may negatively affect surgical outcome. Anaesthesia including clonidine as an adjuntive hypotensive agent may reduce intraoperative bleeding. Methods: A randomised comparison of clonidine-based vs remifentanil-based hypotensive anaesthetic regimen was conducted in patients undergoing FESS. The main assessment was the proportion of subjects with Boezaart scores of surgical field bleeding, as blindly assessed from video recordings by a third surgeon not involved in patient care. Results: A total of 47 subjects underwent FESS and were randomised to clonidine or remifentanil. A significantly lower proportion of patients in the clonidine arm had blindly-assessed Boezaart scores higher than 2, with significantly lower mean blind Boezaart scores at 60 minutes and at 120 minutes. Similar findings were reported by the operating surgeon, and when Wormald and VAS scores were used. Objective estimates of bleeding and the duration of surgery and anaesthesia did not differ between groups. Conclusion: The use of clonidine-based controlled hypotensive anaesthesia achieves lower surgical field bleeding during FESS.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://i3pt.portalinvestigacion.com/publicaciones/5643
url https://i3pt.portalinvestigacion.com/publicaciones/5643
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv INT RHINOLOGIC SOC
publisher.none.fl_str_mv INT RHINOLOGIC SOC
dc.source.none.fl_str_mv RHINOLOGY
ISSN: 03000729
reponame:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
instname:Institut d'Investigació i Innovació Parc Taulí (I3PT)
instname_str Institut d'Investigació i Innovació Parc Taulí (I3PT)
reponame_str r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
collection r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869411332569169920
score 15,811543

Similares en LA Referencia