Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission

On behalf of Gregorio Marañón Microbiology-ID COVID 19 Study Group.

Detalhes bibliográficos
Autores: Pérez-Lago, Laura, Pérez Latorre, Leire, Herranz, Marta, Tejerina, Francisco, Sola-Campoy, Pedro J., Sicilia, Jon, Suárez-González, Julia, Andrés-Zayas, Cristina, Chiner-Oms, Álvaro, Jiménez-Serrano, Santiago, García-González, Neris, Comas, Iñaki, González-Candelas, Fernando, Martínez-Laperche, Carolina, Catalán, Pilar, Muñoz, Patricia, García de Viedma, Darío
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/224908
Acesso em linha:http://hdl.handle.net/10261/224908
Access Level:Acceso aberto
Palavra-chave:COVID-19
Reinfection
Transmission
Epidemiology
Genomics
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spelling Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmissionPérez-Lago, LauraPérez Latorre, LeireHerranz, MartaTejerina, FranciscoSola-Campoy, Pedro J.Sicilia, JonSuárez-González, JuliaAndrés-Zayas, CristinaChiner-Oms, ÁlvaroJiménez-Serrano, SantiagoGarcía-González, NerisComas, IñakiGonzález-Candelas, FernandoMartínez-Laperche, CarolinaCatalán, PilarMuñoz, PatriciaGarcía de Viedma, DaríoCOVID-19ReinfectionTransmissionEpidemiologyGenomicsOn behalf of Gregorio Marañón Microbiology-ID COVID 19 Study Group.The first descriptions of reinfection by SARS-CoV-2 have been recently reported. However, these studies focus exclusively on the reinfected case, without considering the epidemiological context of the event. We present the first complete analysis of the epidemiological scenario around a reinfection by SARS-CoV-2, including three cases preceding the reinfection, the reinfected case per se, and the subsequent transmission to another seven cases. Our analysis is supported by host genetics, viral whole genome sequencing, phylogenomic population analysis, and refined epidemiological data obtained from in-depth interviews with the involved subjects. The reinfection involved a 53-year-old woman with asthma, with a first COVID-19 episode in April 2020 and a much more severe second episode four months and a half later, with COVID-19 seroconversion in August, and requiring hospital admission.This work was supported by Instituto de Salud Carlos III (Ref COV20/00140: SeqCOVID - Consorcio para la epidemiología genómica de SARS-CoV-2 en España) and by Consejo Superior de Investigaciones Cientícas (CSIC) (PTI Salud Global) . Miguel Servet Contract CP15/00075) to LPL.NoAmerican Society for MicrobiologyInstituto de Salud Carlos IIIConsejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202020202021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/224908reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1128/mSphere.00596-21Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2249082026-05-22T06:33:51Z
dc.title.none.fl_str_mv Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
title Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
spellingShingle Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
Pérez-Lago, Laura
COVID-19
Reinfection
Transmission
Epidemiology
Genomics
title_short Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
title_full Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
title_fullStr Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
title_full_unstemmed Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
title_sort Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission
dc.creator.none.fl_str_mv Pérez-Lago, Laura
Pérez Latorre, Leire
Herranz, Marta
Tejerina, Francisco
Sola-Campoy, Pedro J.
Sicilia, Jon
Suárez-González, Julia
Andrés-Zayas, Cristina
Chiner-Oms, Álvaro
Jiménez-Serrano, Santiago
García-González, Neris
Comas, Iñaki
González-Candelas, Fernando
Martínez-Laperche, Carolina
Catalán, Pilar
Muñoz, Patricia
García de Viedma, Darío
author Pérez-Lago, Laura
author_facet Pérez-Lago, Laura
Pérez Latorre, Leire
Herranz, Marta
Tejerina, Francisco
Sola-Campoy, Pedro J.
Sicilia, Jon
Suárez-González, Julia
Andrés-Zayas, Cristina
Chiner-Oms, Álvaro
Jiménez-Serrano, Santiago
García-González, Neris
Comas, Iñaki
González-Candelas, Fernando
Martínez-Laperche, Carolina
Catalán, Pilar
Muñoz, Patricia
García de Viedma, Darío
author_role author
author2 Pérez Latorre, Leire
Herranz, Marta
Tejerina, Francisco
Sola-Campoy, Pedro J.
Sicilia, Jon
Suárez-González, Julia
Andrés-Zayas, Cristina
Chiner-Oms, Álvaro
Jiménez-Serrano, Santiago
García-González, Neris
Comas, Iñaki
González-Candelas, Fernando
Martínez-Laperche, Carolina
Catalán, Pilar
Muñoz, Patricia
García de Viedma, Darío
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Salud Carlos III
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv COVID-19
Reinfection
Transmission
Epidemiology
Genomics
topic COVID-19
Reinfection
Transmission
Epidemiology
Genomics
description On behalf of Gregorio Marañón Microbiology-ID COVID 19 Study Group.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/224908
url http://hdl.handle.net/10261/224908
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1128/mSphere.00596-21
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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