The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis

The Mediterranean Diet (MeDiet), a healthy, plant-based dietary pattern, is recommended by international scientific organizations for its potential in cardiovascular disease (CVD) prevention.1 However, its underlying mechanisms remain incompletely understood.2 Increased carotid intimamedia thickness...

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Autores: Ruiz León, Ana María, Camafort, Miguel, Sala Vila, Aleix, Gilabert, Rosa, Núñez, Isabel, Castro-Barquero, Sara, Fitó Colomer, Montserrat, Lamuela Raventós, Rosa Ma., Pintó Sala, Xavier, Garcia-Arellano, Ana, Ros Rahola, Emilio, Estruch Riba, Ramon, Casas Rodríguez, Rosa M.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/223649
Acceso en línea:https://hdl.handle.net/2445/223649
Access Level:acceso abierto
Palabra clave:Aterosclerosi
Malalties cardiovasculars
Cuina mediterrània
Atherosclerosis
Cardiovascular diseases
Mediterranean cooking
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spelling The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosisRuiz León, Ana MaríaCamafort, MiguelSala Vila, AleixGilabert, RosaNúñez, IsabelCastro-Barquero, SaraFitó Colomer, MontserratLamuela Raventós, Rosa Ma.Pintó Sala, XavierGarcia-Arellano, AnaRos Rahola, EmilioEstruch Riba, RamonCasas Rodríguez, Rosa M.AterosclerosiMalalties cardiovascularsCuina mediterràniaAtherosclerosisCardiovascular diseasesMediterranean cookingThe Mediterranean Diet (MeDiet), a healthy, plant-based dietary pattern, is recommended by international scientific organizations for its potential in cardiovascular disease (CVD) prevention.1 However, its underlying mechanisms remain incompletely understood.2 Increased carotid intimamedia thickness (CIMT), plaque height and inflammation are recognized as indicators of cardiovascular risk.3,4 Results of previous studies indicate that following the MeDiet may slow CIMT and carotid plaque progression5 and improve vascular inflammation.6 However, to our knowledge, no published studies have assessed whether changes in inflammatory biomarkers resulting from long-term MeDiet intervention correlate with changes in CIMT and plaque height. We hypothesize that MeDiet’s beneficial impact on atherosclerosis—through improving CIMT and plaque height— correlates with its immunomodulatory effects on inflammation and plaque stability-related moleculesOxford University Press2025202520252025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion3 p.application/pdfhttps://hdl.handle.net/2445/223649Articles publicats en revistes (Medicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1093/cvr/cvaf027Cardiovascular Research, 2025, vol. 121, num.6, p. 847-850https://doi.org/10.1093/cvr/cvaf027cc by (c) Ruiz León, Ana María, 2025http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2236492026-05-29T05:05:01Z
dc.title.none.fl_str_mv The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
title The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
spellingShingle The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
Ruiz León, Ana María
Aterosclerosi
Malalties cardiovasculars
Cuina mediterrània
Atherosclerosis
Cardiovascular diseases
Mediterranean cooking
title_short The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
title_full The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
title_fullStr The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
title_full_unstemmed The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
title_sort The Mediterranean diet displays an immunomodulatory effect that correlates with beneficial changes in carotid atherosclerosis
dc.creator.none.fl_str_mv Ruiz León, Ana María
Camafort, Miguel
Sala Vila, Aleix
Gilabert, Rosa
Núñez, Isabel
Castro-Barquero, Sara
Fitó Colomer, Montserrat
Lamuela Raventós, Rosa Ma.
Pintó Sala, Xavier
Garcia-Arellano, Ana
Ros Rahola, Emilio
Estruch Riba, Ramon
Casas Rodríguez, Rosa M.
author Ruiz León, Ana María
author_facet Ruiz León, Ana María
Camafort, Miguel
Sala Vila, Aleix
Gilabert, Rosa
Núñez, Isabel
Castro-Barquero, Sara
Fitó Colomer, Montserrat
Lamuela Raventós, Rosa Ma.
Pintó Sala, Xavier
Garcia-Arellano, Ana
Ros Rahola, Emilio
Estruch Riba, Ramon
Casas Rodríguez, Rosa M.
author_role author
author2 Camafort, Miguel
Sala Vila, Aleix
Gilabert, Rosa
Núñez, Isabel
Castro-Barquero, Sara
Fitó Colomer, Montserrat
Lamuela Raventós, Rosa Ma.
Pintó Sala, Xavier
Garcia-Arellano, Ana
Ros Rahola, Emilio
Estruch Riba, Ramon
Casas Rodríguez, Rosa M.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Aterosclerosi
Malalties cardiovasculars
Cuina mediterrània
Atherosclerosis
Cardiovascular diseases
Mediterranean cooking
topic Aterosclerosi
Malalties cardiovasculars
Cuina mediterrània
Atherosclerosis
Cardiovascular diseases
Mediterranean cooking
description The Mediterranean Diet (MeDiet), a healthy, plant-based dietary pattern, is recommended by international scientific organizations for its potential in cardiovascular disease (CVD) prevention.1 However, its underlying mechanisms remain incompletely understood.2 Increased carotid intimamedia thickness (CIMT), plaque height and inflammation are recognized as indicators of cardiovascular risk.3,4 Results of previous studies indicate that following the MeDiet may slow CIMT and carotid plaque progression5 and improve vascular inflammation.6 However, to our knowledge, no published studies have assessed whether changes in inflammatory biomarkers resulting from long-term MeDiet intervention correlate with changes in CIMT and plaque height. We hypothesize that MeDiet’s beneficial impact on atherosclerosis—through improving CIMT and plaque height— correlates with its immunomodulatory effects on inflammation and plaque stability-related molecules
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/223649
url https://hdl.handle.net/2445/223649
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1093/cvr/cvaf027
Cardiovascular Research, 2025, vol. 121, num.6, p. 847-850
https://doi.org/10.1093/cvr/cvaf027
dc.rights.none.fl_str_mv cc by (c) Ruiz León, Ana María, 2025
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Ruiz León, Ana María, 2025
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 3 p.
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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