A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type

[EN] All variables affecting the morphology of mesoporous silica nanoparticles (MSN) should be carefully analyzed in order to truly tailored design their mesoporous structure according to their final use. Although complete control on MCM-41 synthesis has been already claimed, reproducibility and rep...

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Autores: Beltrán-Osuna, A.A., Perilla-Perilla, Jairo Ernesto, Gómez Ribelles, José Luís|||0000-0001-9099-0885
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/101858
Acceso en línea:https://riunet.upv.es/handle/10251/101858
Access Level:acceso abierto
Palabra clave:MSN
Partially opened system
Reaction volume
Stirring rate
MCM-41
Mesoporous silica nanoarticles
MAQUINAS Y MOTORES TERMICOS
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spelling A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 typeBeltrán-Osuna, A.A.Perilla-Perilla, Jairo ErnestoGómez Ribelles, José Luís|||0000-0001-9099-0885MSNPartially opened systemReaction volumeStirring rateMCM-41Mesoporous silica nanoarticlesMAQUINAS Y MOTORES TERMICOS[EN] All variables affecting the morphology of mesoporous silica nanoparticles (MSN) should be carefully analyzed in order to truly tailored design their mesoporous structure according to their final use. Although complete control on MCM-41 synthesis has been already claimed, reproducibility and repeatability of results remain a big issue due to the lack of information reported in literature. Stirring rate, reaction volume, and system configuration (i.e., opened or closed reactor) are three variables that are usually omitted, making the comparison of product characteristics difficult. Specifically, the rate of solvent evaporation is seldom disclosed, and its influence has not been previously analyzed. These variables were systematically studied in this work, and they were proven to have a fundamental impact on final particle morphology. Hence, a high degree of circularity (C = 0.97) and monodispersed particle size distributions were only achieved when a stirring speed of 500 rpm and a reaction scale of 500 mL were used in a partially opened system, for a 2 h reaction at 80 degrees C. Well-shaped spherical mesoporous silica nanoparticles with a diameter of 95 nm, a pore size of 2.8 nm, and a total surface area of 954 m(2) g(-1) were obtained. Final characteristics made this product suitable to be used in biomedicine and nanopharmaceutics, especially for the design of drug delivery systems.This study was funded partially by Departamento Administrativo de Ciencia Tecnología e Innovación–COLCIENCIAS (recipient, Angela A. Beltrán-Osuna); Ministerio de Economía y Competitividad, MINECO, research number MAT2016-76039-C4-1-R (Recipient, José L. Gómez-Ribelles); and Universidad Nacional de Colombia, grant number DIB201010021438 (Recipient, Jairo E. Perilla).Springer-VerlagDepartamento de Termodinámica AplicadaCentro de Biomateriales e Ingeniería TisularEscuela Técnica Superior de Ingeniería IndustrialDepartamento Administrativo de Ciencia, Tecnología e Innovación, ColombiaUniversidad Nacional de ColombiaMinisterio de Economía y CompetitividadRepositorio Institucional de la Universitat Politècnica de València Riunet20172017-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://riunet.upv.es/handle/10251/101858reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 MAT2016-76039-C4-1-R BIOMATERIALES PIEZOELECTRICOS PARA LA DIFERENCIACION CELULAR EN INTERFASES CELULA-MATERIAL ELECTRICAMENTE ACTIVASUniversidad Nacional de Colombia https://doi.org/10.13039/501100002753 DIB 201010021438open accesshttp://purl.org/coar/access_right/c_abf2Reserva de todos los derechoshttp://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/1018582026-06-13T07:49:27Z
dc.title.none.fl_str_mv A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
title A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
spellingShingle A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
Beltrán-Osuna, A.A.
MSN
Partially opened system
Reaction volume
Stirring rate
MCM-41
Mesoporous silica nanoarticles
MAQUINAS Y MOTORES TERMICOS
title_short A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
title_full A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
title_fullStr A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
title_full_unstemmed A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
title_sort A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type
dc.creator.none.fl_str_mv Beltrán-Osuna, A.A.
Perilla-Perilla, Jairo Ernesto
Gómez Ribelles, José Luís|||0000-0001-9099-0885
author Beltrán-Osuna, A.A.
author_facet Beltrán-Osuna, A.A.
Perilla-Perilla, Jairo Ernesto
Gómez Ribelles, José Luís|||0000-0001-9099-0885
author_role author
author2 Perilla-Perilla, Jairo Ernesto
Gómez Ribelles, José Luís|||0000-0001-9099-0885
author2_role author
author
dc.contributor.none.fl_str_mv Departamento de Termodinámica Aplicada
Centro de Biomateriales e Ingeniería Tisular
Escuela Técnica Superior de Ingeniería Industrial
Departamento Administrativo de Ciencia, Tecnología e Innovación, Colombia
Universidad Nacional de Colombia
Ministerio de Economía y Competitividad
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv MSN
Partially opened system
Reaction volume
Stirring rate
MCM-41
Mesoporous silica nanoarticles
MAQUINAS Y MOTORES TERMICOS
topic MSN
Partially opened system
Reaction volume
Stirring rate
MCM-41
Mesoporous silica nanoarticles
MAQUINAS Y MOTORES TERMICOS
description [EN] All variables affecting the morphology of mesoporous silica nanoparticles (MSN) should be carefully analyzed in order to truly tailored design their mesoporous structure according to their final use. Although complete control on MCM-41 synthesis has been already claimed, reproducibility and repeatability of results remain a big issue due to the lack of information reported in literature. Stirring rate, reaction volume, and system configuration (i.e., opened or closed reactor) are three variables that are usually omitted, making the comparison of product characteristics difficult. Specifically, the rate of solvent evaporation is seldom disclosed, and its influence has not been previously analyzed. These variables were systematically studied in this work, and they were proven to have a fundamental impact on final particle morphology. Hence, a high degree of circularity (C = 0.97) and monodispersed particle size distributions were only achieved when a stirring speed of 500 rpm and a reaction scale of 500 mL were used in a partially opened system, for a 2 h reaction at 80 degrees C. Well-shaped spherical mesoporous silica nanoparticles with a diameter of 95 nm, a pore size of 2.8 nm, and a total surface area of 954 m(2) g(-1) were obtained. Final characteristics made this product suitable to be used in biomedicine and nanopharmaceutics, especially for the design of drug delivery systems.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/101858
url https://riunet.upv.es/handle/10251/101858
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 MAT2016-76039-C4-1-R BIOMATERIALES PIEZOELECTRICOS PARA LA DIFERENCIACION CELULAR EN INTERFASES CELULA-MATERIAL ELECTRICAMENTE ACTIVAS
Universidad Nacional de Colombia https://doi.org/10.13039/501100002753 DIB 201010021438
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer-Verlag
publisher.none.fl_str_mv Springer-Verlag
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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