Oleanolic acid bioavailability in human serum

[Description of methods used for collection/generation of data] 1. Extraction and GC-MS determination (DOI 10.1002/bmc.3480); 2. UV Spectrophotometry method for OA-HSA association (DOI 10.1021/jf1039537); 3. Enzymatic methods were used to determine serum glucose, total cholesterol, HDL and triglycer...

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Detalles Bibliográficos
Autores: García-González, Aída, Espinosa, Juan M., Cerrillo, Isabel, Montero Romero, Emilio, Rivas-Melo, Juan José, Romero-Báez, Andrea, Jiménez-Andreu, María Dolores, Ruíz-Trillo, Carmen Amelia, Rodríguez-Rodríguez, Ana, Martínez-Ortega, Antonio Jesús, Roque-Cuellar, María Del Carmen, García-Rey, Silvia, Jiménez-Sánchez, Andrés, Mangas-Cruz, Miguel Ángel, Pereira-Cunill, José Luis, Perona, Javier S., García-Luna, Pedro Pablo, Castellano, José María
Tipo de recurso: conjunto de datos
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/335582
Acceso en línea:http://hdl.handle.net/10261/335582
https://doi.org/10.20350/digitalCSIC/15571
Access Level:acceso abierto
Palabra clave:Oleanolic acid
Bioavailability in humans
Pharmacokinetics
NCT05529953
Postprandial trial
Human serum proteins
Human triglyceride-rich lipoproteins
Descripción
Sumario:[Description of methods used for collection/generation of data] 1. Extraction and GC-MS determination (DOI 10.1002/bmc.3480); 2. UV Spectrophotometry method for OA-HSA association (DOI 10.1021/jf1039537); 3. Enzymatic methods were used to determine serum glucose, total cholesterol, HDL and triglycerides, whereas LDL was estimated by the Friedewald formula (14). Total lipoprotein Apo B (Apo B48 + Apo B100) was quantified by an immunoturbidimetric assay (Tinaquant; Roche Diagnostics, Mannheim, Germany), and serum insulin using an ELISA kit (Diaclone, Besançon, France).

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