Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study

PurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to ident...

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Autores: Sánchez Haro, Edward, Vela, Emili, Cleries, Montserrat, Vela Bernal, Sandra, Tapiolas, Ingrid, Troya Díaz, José, Julián Ibáñez, Joan Francesc, Parés Martínez, David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/205224
Acceso en línea:https://hdl.handle.net/2445/205224
Access Level:acceso abierto
Palabra clave:Fístules
Abscessos
Fistula
Abscess
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spelling Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based studySánchez Haro, EdwardVela, EmiliCleries, MontserratVela Bernal, SandraTapiolas, IngridTroya Díaz, JoséJulián Ibáñez, Joan FrancescParés Martínez, DavidFístulesAbscessosFistulaAbscessPurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to identify potential risk factors associated with demographic, socioeconomic and pre-existing disease (e.g. diabetes and inflammatory bowel disease).MethodsA longitudinal observational study was designed including a large cohort study in an area with 7,553,650 inhabitants in Spain 1st january 2014 to 31st december 2019. Adults who attended for the first time with an anorectal abscess and had a minimum of 1-year follow-up were included. The diagnosis was made using ICD-10 codes for anorectal abscess and anal fistula.ResultsDuring the study period, we included 27,821 patients with anorectal abscess. There was a predominance of men (70%) and an overall incidence of 596 per million population. The overall incidence of anal fistula developing from abscesses was 20%, with predominance in men, and a lower incidence in the lowest income level. The cumulative incidence of fistula was higher in men and in younger patients (p < 0.0001). On multivariate analysis, patients aged 60-69 years (hazard ratio 2.0) and those with inflammatory bowel disease (hazard ratio 1.8-2.0) had a strong association with fistula development (hazard ratio 2.0).ConclusionsOne in five patients with an anorectal abscess will develop a fistula, with a higher likelihood in men. Fistula formation was strongly associated with inflammatory bowel disease.Springer Science and Business Media LLC2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/205224Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1007/s10151-023-02840-zTechniques in Coloproctology, 2023, vol. 27, num. 10, p. 897-907https://doi.org/10.1007/s10151-023-02840-zcc by (c) Sánchez Haro, Edward et al, 2023http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/2052242026-05-27T06:46:51Z
dc.title.none.fl_str_mv Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
title Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
spellingShingle Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
Sánchez Haro, Edward
Fístules
Abscessos
Fistula
Abscess
title_short Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
title_full Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
title_fullStr Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
title_full_unstemmed Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
title_sort Clinical characterization of patients with anal fistula during follow-up of anorectal abscess: a large population-based study
dc.creator.none.fl_str_mv Sánchez Haro, Edward
Vela, Emili
Cleries, Montserrat
Vela Bernal, Sandra
Tapiolas, Ingrid
Troya Díaz, José
Julián Ibáñez, Joan Francesc
Parés Martínez, David
author Sánchez Haro, Edward
author_facet Sánchez Haro, Edward
Vela, Emili
Cleries, Montserrat
Vela Bernal, Sandra
Tapiolas, Ingrid
Troya Díaz, José
Julián Ibáñez, Joan Francesc
Parés Martínez, David
author_role author
author2 Vela, Emili
Cleries, Montserrat
Vela Bernal, Sandra
Tapiolas, Ingrid
Troya Díaz, José
Julián Ibáñez, Joan Francesc
Parés Martínez, David
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Fístules
Abscessos
Fistula
Abscess
topic Fístules
Abscessos
Fistula
Abscess
description PurposeApproximately 15-50% of patients with an anorectal abscess will develop an anal fistula, but the true incidence of this entity is currently unknown. The aim of the study was to determine the incidence of anorectal abscess and development of a fistula in a specific population area and to identify potential risk factors associated with demographic, socioeconomic and pre-existing disease (e.g. diabetes and inflammatory bowel disease).MethodsA longitudinal observational study was designed including a large cohort study in an area with 7,553,650 inhabitants in Spain 1st january 2014 to 31st december 2019. Adults who attended for the first time with an anorectal abscess and had a minimum of 1-year follow-up were included. The diagnosis was made using ICD-10 codes for anorectal abscess and anal fistula.ResultsDuring the study period, we included 27,821 patients with anorectal abscess. There was a predominance of men (70%) and an overall incidence of 596 per million population. The overall incidence of anal fistula developing from abscesses was 20%, with predominance in men, and a lower incidence in the lowest income level. The cumulative incidence of fistula was higher in men and in younger patients (p < 0.0001). On multivariate analysis, patients aged 60-69 years (hazard ratio 2.0) and those with inflammatory bowel disease (hazard ratio 1.8-2.0) had a strong association with fistula development (hazard ratio 2.0).ConclusionsOne in five patients with an anorectal abscess will develop a fistula, with a higher likelihood in men. Fistula formation was strongly associated with inflammatory bowel disease.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/205224
url https://hdl.handle.net/2445/205224
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1007/s10151-023-02840-z
Techniques in Coloproctology, 2023, vol. 27, num. 10, p. 897-907
https://doi.org/10.1007/s10151-023-02840-z
dc.rights.none.fl_str_mv cc by (c) Sánchez Haro, Edward et al, 2023
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Sánchez Haro, Edward et al, 2023
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Science and Business Media LLC
publisher.none.fl_str_mv Springer Science and Business Media LLC
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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