Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications

This work was supported by the Spanish Government through project MAT2015-67183- R, cofounded by the EU through the European Regional Development Funds. The authors acknowledge also the Generalitat de Catalunya for funding the project 2017SGR-1165 and for the ICREA Award of M-P Ginebra.

Detalles Bibliográficos
Autores: Guillem Martí, Jordi, Cinca, Núria, Punset Fuste, Miquel, García Cano, Irene, Gil Mur, Francisco Javier, Guilemany, José Maria, Dosta, Sergi
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12328/1051
Acceso en línea:http://hdl.handle.net/20.500.12328/1051
https://doi.org/10.1016/j.colsurfb.2019.04.048
Access Level:acceso abierto
Palabra clave:Titani
Titanio
Titanium
Materials biomèdics
Biomedical materials
Materiales biomédicos
Hydroxyapatite coating
54
61
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spelling Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applicationsGuillem Martí, JordiCinca, NúriaPunset Fuste, MiquelGarcía Cano, IreneGil Mur, Francisco JavierGuilemany, José MariaDosta, SergiTitaniTitanioTitaniumMaterials biomèdicsBiomedical materialsMateriales biomédicosHydroxyapatite coating5461This work was supported by the Spanish Government through project MAT2015-67183- R, cofounded by the EU through the European Regional Development Funds. The authors acknowledge also the Generalitat de Catalunya for funding the project 2017SGR-1165 and for the ICREA Award of M-P Ginebra.The lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome this limitation is the coating of Ti with hydroxyapatite (HA), which presents similar chemical composition than bone. Nonetheless, most of the strategies currently used generate a non-stable coating and may produce the formation of amorphous phases when high temperatures are used. Herein, we proposed to generate a Ti-HA composite coating on Ti surface to improve the stability of the bioactive coating. The coating was produced by cold gas spraying, which uses relatively low temperatures, and compared to a Ti coating. The coating was thoroughly characterized in terms of morphology, roughness, porosity and phase composition. In addition, the coating was mechanically characterized using a tensile loading machine. Finally, biological response was evaluated after seeding SaOS-2 osteoblasts and measuring cell adhesion, proliferation and differentiation. The novel Ti-HA coating presented high porosity and high adhesion and bond strengths. No change in HA phases was observed after coating formation. Moreover, osteoblast-like cells adhered, proliferated and differentiated on Ti-HA coated surfaces suggesting that the novel coating might be a good candidate for biomedical applications.info:eu-repo/semantics/acceptedVersionElsevier2019info:eu-repo/semantics/article33http://hdl.handle.net/20.500.12328/1051https://doi.org/10.1016/j.colsurfb.2019.04.048reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésColloids and Surfaces B: Biointerfaces180;info:eu-repo/grantAgreement/ES/1PE/MAT2015-67183-Rhttp://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:20.500.12328/10512026-05-29T05:05:01Z
dc.title.none.fl_str_mv Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
title Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
spellingShingle Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
Guillem Martí, Jordi
Titani
Titanio
Titanium
Materials biomèdics
Biomedical materials
Materiales biomédicos
Hydroxyapatite coating
54
61
title_short Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
title_full Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
title_fullStr Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
title_full_unstemmed Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
title_sort Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
dc.creator.none.fl_str_mv Guillem Martí, Jordi
Cinca, Núria
Punset Fuste, Miquel
García Cano, Irene
Gil Mur, Francisco Javier
Guilemany, José Maria
Dosta, Sergi
author Guillem Martí, Jordi
author_facet Guillem Martí, Jordi
Cinca, Núria
Punset Fuste, Miquel
García Cano, Irene
Gil Mur, Francisco Javier
Guilemany, José Maria
Dosta, Sergi
author_role author
author2 Cinca, Núria
Punset Fuste, Miquel
García Cano, Irene
Gil Mur, Francisco Javier
Guilemany, José Maria
Dosta, Sergi
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Titani
Titanio
Titanium
Materials biomèdics
Biomedical materials
Materiales biomédicos
Hydroxyapatite coating
54
61
topic Titani
Titanio
Titanium
Materials biomèdics
Biomedical materials
Materiales biomédicos
Hydroxyapatite coating
54
61
description This work was supported by the Spanish Government through project MAT2015-67183- R, cofounded by the EU through the European Regional Development Funds. The authors acknowledge also the Generalitat de Catalunya for funding the project 2017SGR-1165 and for the ICREA Award of M-P Ginebra.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12328/1051
https://doi.org/10.1016/j.colsurfb.2019.04.048
url http://hdl.handle.net/20.500.12328/1051
https://doi.org/10.1016/j.colsurfb.2019.04.048
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Colloids and Surfaces B: Biointerfaces
180;
info:eu-repo/grantAgreement/ES/1PE/MAT2015-67183-R
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 33
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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