Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283

© 2022 European Food Safety Authority. EFSA Journal Published by Wiley-VCH GmbH on behalf of European Food Safety Authority

Detalles Bibliográficos
Autores: Turck, Dominique, Bohn, Torsten, Castenmiller, Jacqueline, De Henauw, Stefaan, Hirsch‐Ernst, Karen Ildico, Maciuk, Alexandre, Mangelsdorf, Inge, McArdle, Harry J, Naska, Androniki, Peláez, Carmen, Pentieva, Kristina, Siani, Alfonso, Thies, Frank, Tsabouri, Sophia, Vinceti, Marco, Cubadda, Francesco, Frenzel, Thomas, Heinonen, Marina, Marchelli, Rosangela, Neuhäuser‐Berthold, Monika, Poulsen, Morten, Prieto Maradona, Miguel, Schlatter, Josef Rudolf, Loveren, Henk van, Colombo, Paolo, Noriega Fernández, Estefanía, Knutsen, Helle Katrine
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universidad de León
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/20500
Acceso en línea:https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2022.7140
https://hdl.handle.net/10612/20500
Access Level:acceso abierto
Palabra clave:Tecnología de los alimentos
2’-fucosyllactose/difucosyllactose
Lacto-N-tetraose
HiMO
Novel Foods
Food supplement
Extension of use
Infants
3206 Ciencias de la Nutrición
3309 Tecnología de Los Alimentos
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oai_identifier_str oai:buleria.unileon.es:10612/20500
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spelling Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283Turck, DominiqueBohn, TorstenCastenmiller, JacquelineDe Henauw, StefaanHirsch‐Ernst, Karen IldicoMaciuk, AlexandreMangelsdorf, IngeMcArdle, Harry JNaska, AndronikiPeláez, CarmenPentieva, KristinaSiani, AlfonsoThies, FrankTsabouri, SophiaVinceti, MarcoCubadda, FrancescoFrenzel, ThomasHeinonen, MarinaMarchelli, RosangelaNeuhäuser‐Berthold, MonikaPoulsen, MortenPrieto Maradona, MiguelSchlatter, Josef RudolfLoveren, Henk vanColombo, PaoloNoriega Fernández, EstefaníaKnutsen, Helle KatrineTecnología de los alimentos2’-fucosyllactose/difucosyllactoseLacto-N-tetraoseHiMONovel FoodsFood supplementExtension of useInfants3206 Ciencias de la Nutrición3309 Tecnología de Los Alimentos© 2022 European Food Safety Authority. EFSA Journal Published by Wiley-VCH GmbH on behalf of European Food Safety Authority[EN] Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of the extensions of use of the authorised novel foods (NFs) 2’-fucosyllactose/difucosyllactose (2’-FL/DFL) mixture and lacto-N-tetraose (LNT) in food supplements (FS) for infants pursuant to Regulation (EU) 2015/2283. The NFs are produced by fermentation with genetically modified strains of Escherichia coli K-12 DH1 and already included in the EU list of NF. The applicant stated that no changes in the production process or the identity of the NFs occurred. The applicant proposes an extension of use of the NF containing 2’-FL/DFL mixture in FS intended for infants (< 1 year), at a maximum use level of 1.6 g/day for infants ≤ 6 months and up to 1.2 g/day for infants > 6 months. The applicant also proposes an extension of use of LNT in FS intended for infants (< 1 year), at a maximum use level of 0.8 g/day for infants ≤ 6 months and up to 0.6 g/day for infants > 6 months. The intake per kg body weight of 2’-FL/DFL and LNT from the proposed maximum use levels of the respective NFs in FS for infants does not exceed the lowest estimated mean intake of naturally occurring 2’-FL/DFL and it is similar to the highest estimated mean intake of LNT by breastfed infants. In addition, the Panel notes that the proposed uses of the NFs in FS for infants result in lower maximum daily intakes than those from the already authorised uses of the NFs for the same population group. The Panel concludes that the uses of the NFs containing either 2’-FL/DFL or LNT in FS for infants are safe under the proposed conditions of use.SIWiley Open AccessNutricion y BromatologiaFacultad de Veterinaria2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2022.7140https://hdl.handle.net/10612/20500reponame:BULERIA. Repositorio Institucional de la Universidad de Leóninstname:Universidad de LeónIngléshttp://creativecommons.org/licenses/by-nd/4.0/info:eu-repo/semantics/openAccessoai:buleria.unileon.es:10612/205002026-06-24T12:43:27Z
dc.title.none.fl_str_mv Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
title Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
spellingShingle Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
Turck, Dominique
Tecnología de los alimentos
2’-fucosyllactose/difucosyllactose
Lacto-N-tetraose
HiMO
Novel Foods
Food supplement
Extension of use
Infants
3206 Ciencias de la Nutrición
3309 Tecnología de Los Alimentos
title_short Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
title_full Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
title_fullStr Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
title_full_unstemmed Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
title_sort Safety of the extension of use of 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture and lacto‐N‐tetraose (LNT) as novel foods in food supplements for infants pursuant to Regulation (EU) 2015/2283
dc.creator.none.fl_str_mv Turck, Dominique
Bohn, Torsten
Castenmiller, Jacqueline
De Henauw, Stefaan
Hirsch‐Ernst, Karen Ildico
Maciuk, Alexandre
Mangelsdorf, Inge
McArdle, Harry J
Naska, Androniki
Peláez, Carmen
Pentieva, Kristina
Siani, Alfonso
Thies, Frank
Tsabouri, Sophia
Vinceti, Marco
Cubadda, Francesco
Frenzel, Thomas
Heinonen, Marina
Marchelli, Rosangela
Neuhäuser‐Berthold, Monika
Poulsen, Morten
Prieto Maradona, Miguel
Schlatter, Josef Rudolf
Loveren, Henk van
Colombo, Paolo
Noriega Fernández, Estefanía
Knutsen, Helle Katrine
author Turck, Dominique
author_facet Turck, Dominique
Bohn, Torsten
Castenmiller, Jacqueline
De Henauw, Stefaan
Hirsch‐Ernst, Karen Ildico
Maciuk, Alexandre
Mangelsdorf, Inge
McArdle, Harry J
Naska, Androniki
Peláez, Carmen
Pentieva, Kristina
Siani, Alfonso
Thies, Frank
Tsabouri, Sophia
Vinceti, Marco
Cubadda, Francesco
Frenzel, Thomas
Heinonen, Marina
Marchelli, Rosangela
Neuhäuser‐Berthold, Monika
Poulsen, Morten
Prieto Maradona, Miguel
Schlatter, Josef Rudolf
Loveren, Henk van
Colombo, Paolo
Noriega Fernández, Estefanía
Knutsen, Helle Katrine
author_role author
author2 Bohn, Torsten
Castenmiller, Jacqueline
De Henauw, Stefaan
Hirsch‐Ernst, Karen Ildico
Maciuk, Alexandre
Mangelsdorf, Inge
McArdle, Harry J
Naska, Androniki
Peláez, Carmen
Pentieva, Kristina
Siani, Alfonso
Thies, Frank
Tsabouri, Sophia
Vinceti, Marco
Cubadda, Francesco
Frenzel, Thomas
Heinonen, Marina
Marchelli, Rosangela
Neuhäuser‐Berthold, Monika
Poulsen, Morten
Prieto Maradona, Miguel
Schlatter, Josef Rudolf
Loveren, Henk van
Colombo, Paolo
Noriega Fernández, Estefanía
Knutsen, Helle Katrine
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Nutricion y Bromatologia
Facultad de Veterinaria
dc.subject.none.fl_str_mv Tecnología de los alimentos
2’-fucosyllactose/difucosyllactose
Lacto-N-tetraose
HiMO
Novel Foods
Food supplement
Extension of use
Infants
3206 Ciencias de la Nutrición
3309 Tecnología de Los Alimentos
topic Tecnología de los alimentos
2’-fucosyllactose/difucosyllactose
Lacto-N-tetraose
HiMO
Novel Foods
Food supplement
Extension of use
Infants
3206 Ciencias de la Nutrición
3309 Tecnología de Los Alimentos
description © 2022 European Food Safety Authority. EFSA Journal Published by Wiley-VCH GmbH on behalf of European Food Safety Authority
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2022.7140
https://hdl.handle.net/10612/20500
url https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2022.7140
https://hdl.handle.net/10612/20500
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley Open Access
publisher.none.fl_str_mv Wiley Open Access
dc.source.none.fl_str_mv reponame:BULERIA. Repositorio Institucional de la Universidad de León
instname:Universidad de León
instname_str Universidad de León
reponame_str BULERIA. Repositorio Institucional de la Universidad de León
collection BULERIA. Repositorio Institucional de la Universidad de León
repository.name.fl_str_mv
repository.mail.fl_str_mv
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