Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy

A novel combination of adaptive optics with a simultaneous en-face OCT/SLO system for high resolution imaging of the in-vivo human retina is presented. Pairs of retinal images are shown and performance of the system is evaluated with and without dynamic wavefront correction. The adaptive optics clos...

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Bibliographic Details
Authors: Merino, David, Dainty, Chris, Bradu, Adrian, Podoleanu, Adrian
Format: article
Status:Published version
Publication Date:2006
Country:España
Institution:Universitat Oberta de Catalunya (UOC)
Repository:O2, repositorio institucional de la UOC
OAI Identifier:oai:openaccess.uoc.edu:10609/151431
Online Access:http://hdl.handle.net/10609/151431
https://doi.org/10.1364/oe.14.003345
Access Level:Open access
Keyword:adaptive optics
optical coherence tomography
ophthalmic optics
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spelling Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopyMerino, DavidDainty, ChrisBradu, AdrianPodoleanu, Adrianadaptive opticsoptical coherence tomographyophthalmic opticsA novel combination of adaptive optics with a simultaneous en-face OCT/SLO system for high resolution imaging of the in-vivo human retina is presented. Pairs of retinal images are shown and performance of the system is evaluated with and without dynamic wavefront correction. The adaptive optics closed loop system operates at a frame rate of 9 Hz and incorporates a Shack-Hartmann wavefront sensor based on a highly sensitive Andor camera and a 37 actuator OKO membrane deformable mirror to correct for ocular aberrations. The system produces C-scan pairs of images at a frame rate of 2 Hz. The correction of aberrations produced by the adaptive optics closed-loop system increased the signal-to-noise ratio in images obtained from volunteer eyes by up to 6 dB in the OCT channel and up to 9 dB in the SLO channel. A slight improvement in the lateral resolution was also obtained, from 6.5 mum before to 5 mum after closing the adaptive optics loop.Optica Publishing Group202420242006info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10609/151431https://doi.org/10.1364/oe.14.003345reponame:O2, repositorio institucional de la UOCinstname:Universitat Oberta de Catalunya (UOC)InglésOptinc Express, 2006, 14(8)https://doi.org/10.1364/oe.14.003345info:eu-repo/grantAgreement/SFI STAR Award/2006/01info:eu-repo/grantAgreement/EPSRC/2006/GR© 2006 Optical Society of Americainfo:eu-repo/semantics/openAccessoai:openaccess.uoc.edu:10609/1514312026-05-28T12:42:01Z
dc.title.none.fl_str_mv Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
title Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
spellingShingle Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
Merino, David
adaptive optics
optical coherence tomography
ophthalmic optics
title_short Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
title_full Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
title_fullStr Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
title_full_unstemmed Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
title_sort Adaptive optics enhanced simultaneous en-face optical coherence tomography and scanning laser ophthalmoscopy
dc.creator.none.fl_str_mv Merino, David
Dainty, Chris
Bradu, Adrian
Podoleanu, Adrian
author Merino, David
author_facet Merino, David
Dainty, Chris
Bradu, Adrian
Podoleanu, Adrian
author_role author
author2 Dainty, Chris
Bradu, Adrian
Podoleanu, Adrian
author2_role author
author
author
dc.subject.none.fl_str_mv adaptive optics
optical coherence tomography
ophthalmic optics
topic adaptive optics
optical coherence tomography
ophthalmic optics
description A novel combination of adaptive optics with a simultaneous en-face OCT/SLO system for high resolution imaging of the in-vivo human retina is presented. Pairs of retinal images are shown and performance of the system is evaluated with and without dynamic wavefront correction. The adaptive optics closed loop system operates at a frame rate of 9 Hz and incorporates a Shack-Hartmann wavefront sensor based on a highly sensitive Andor camera and a 37 actuator OKO membrane deformable mirror to correct for ocular aberrations. The system produces C-scan pairs of images at a frame rate of 2 Hz. The correction of aberrations produced by the adaptive optics closed-loop system increased the signal-to-noise ratio in images obtained from volunteer eyes by up to 6 dB in the OCT channel and up to 9 dB in the SLO channel. A slight improvement in the lateral resolution was also obtained, from 6.5 mum before to 5 mum after closing the adaptive optics loop.
publishDate 2006
dc.date.none.fl_str_mv 2006
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10609/151431
https://doi.org/10.1364/oe.14.003345
url http://hdl.handle.net/10609/151431
https://doi.org/10.1364/oe.14.003345
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Optinc Express, 2006, 14(8)
https://doi.org/10.1364/oe.14.003345
info:eu-repo/grantAgreement/SFI STAR Award/2006/01
info:eu-repo/grantAgreement/EPSRC/2006/GR
dc.rights.none.fl_str_mv © 2006 Optical Society of America
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © 2006 Optical Society of America
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Optica Publishing Group
publisher.none.fl_str_mv Optica Publishing Group
dc.source.none.fl_str_mv reponame:O2, repositorio institucional de la UOC
instname:Universitat Oberta de Catalunya (UOC)
instname_str Universitat Oberta de Catalunya (UOC)
reponame_str O2, repositorio institucional de la UOC
collection O2, repositorio institucional de la UOC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812455

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