Does age impact outcomes of retrograde intrarenal surgery in the elderly? Results from 366 patients from the FLEXible ureteroscopy outcomes registry (FLEXOR)

BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS:...

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Detalhes bibliográficos
Autores: Giulioni C., Brocca C., Gauhar V., Somani B.K., Chew B.H., Traxer O., Emiliani E., Innoue T., Sarica K., Gadzhiev N., Tanidir Y., Teoh J.Y.-C., Galosi A.B., Castellani D.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p16862
Acesso em linha:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16862
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85170032004&doi=10.1007%2fs40520-023-02545-1&partnerID=40&md5=b44886ea49aceac937f41caf5dc56d75
Access Level:acceso abierto
Palavra-chave:Elderly
Flexible ureteroscopy
Laser
Renal stones
Retrograde intrarenal surgery
Descrição
Resumo:BACKGROUND: There has been a consistent increase in the last decades in prevalence of renal stones in elderly. AIMS: To evaluate outcomes of retrograde intrarenal surgery (RIRS) for renal stones in elderly and factors associated with postoperative complications and residual fragments (RFs). METHODS: Data from 12 centers were retrospectively reviewed. INCLUSION CRITERIA: = 75 years, renal stones only, normal renal anatomy. Patients were divided into three groups; Group 1: patients aged 75-79 years; Group 2: age 80-84 years; Group 3: age = 85 years. Multivariable logistic regression analyses were performed to assess factors associated with perioperative complications, sepsis, and RFs. RESULTS: 366 patients were included. There were 189 patients in Group 1, 113 in Group 2, and 64 in Group 3. There was no difference between groups regarding stone features and total surgical time. Median length of stay was significantly longer in Group 3 (6.0 days, vs 2.0 days in Group 2 vs 2.5 days in Group 1, p = 0.043). There was no significant difference in postoperative complications and RFs between the groups. At multivariable logistic regression analysis, female gender (OR 2.82) and maximum stone diameter (OR 1.14) were associated with higher odds of sepsis, while surgical time (OR 1.12) and the use of a reusable ureteroscope (OR 6.51) with overall complications. Stone size (OR 1.23) was associated with higher odds of RFs. CONCLUSION: RIRS showed safety and efficacy for kidney stones in elderly patients. Surgical time should be kept as short as possible to avoid higher odds of postoperative complications, particularly in females.