Lifestyle and psychologic factors, and pain: a meta-analysis and cohort study

Chronic pain is one of the leading causes of healthcare seeking. It is a multidimensional experience affected by biological, physiological, psychological, social, and contextual factors. In this doctoral thesis, we conducted a dose-response meta-analysis to assess the effect of alcohol consumption o...

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Detalles Bibliográficos
Autor: Karimi, Roya
Tipo de recurso: tesis doctoral
Fecha de publicación:2023
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/30479
Acceso en línea:http://hdl.handle.net/10347/30479
Access Level:acceso abierto
Palabra clave:Materias::Investigación::32 Ciencias médicas::3202 Epidemologia
Materias::Investigación::32 Ciencias médicas::3212 Salud pública
Descripción
Sumario:Chronic pain is one of the leading causes of healthcare seeking. It is a multidimensional experience affected by biological, physiological, psychological, social, and contextual factors. In this doctoral thesis, we conducted a dose-response meta-analysis to assess the effect of alcohol consumption on chronic pain. Also, we evaluated the direct and indirect effects of depression on pain through sleep disturbance using a two-stage meta-analytic structural equation modeling. Furthermore, we conducted a cohort study to assess the impact of the health-related quality of life (well-being) on chronic pain incidence. Finally, we evaluated the causal role of covariates in the association between physical well-being and chronic pain through mediation analysis and stratum-specific analysis.