Global Trends in Norovirus Genotype Distribution among Children with Acute Gastroenteritis.

Noroviruses are a leading cause of acute gastroenteritis (AGE) among adults and children worldwide. NoroSurv is a global network for norovirus strain surveillance among children <5 years of age with AGE. Participants in 16 countries across 6 continents used standardized protocols for dual typing...

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Detalles Bibliográficos
Autores: Cannon, JL, Bonifacio, J, Bucardo, F, Buesa, J, Bruggink, L, Chan, MCW, Fumian, TM, Giri, S, Gonzalez, MD, Hewitt, J, Lin, JH, Mans, J, Munoz, C, Pan, CY, Pang, XL, Pietsch, C, Rahman, M, Sakon, N, Selvarangan, R, Browne, H, Barclay, L, Vinje, J
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p16191
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/16191
Access Level:acceso abierto
Palabra clave:NoroSurv
P-types
acute gastroenteritis
capsids
children
dual typing
enteric infections
food safety
gastroenteritis
genotypes
norovirus
polymerase
surveillance
vaccines
viruses
Descripción
Sumario:Noroviruses are a leading cause of acute gastroenteritis (AGE) among adults and children worldwide. NoroSurv is a global network for norovirus strain surveillance among children <5 years of age with AGE. Participants in 16 countries across 6 continents used standardized protocols for dual typing (genotype and polymerase type) and uploaded 1,325 dual-typed sequences to the NoroSurv web portal during 2016-2020. More than 50% of submitted sequences were GII.4 Sydney[P16] or GII.4 Sydney[P31] strains. Other common strains included GII.2[P16], GII.3[P12], GII.6[P7], and GI.3[P3] viruses. In total, 22 genotypes and 36 dual types, including GII.3 and GII.20 viruses with rarely reported polymerase types, were detected, reflecting high strain diversity. Surveillance data captured in NoroSurv enables the monitoring of trends in norovirus strains associated childhood AGE throughout the world on a near real-time basis.