Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar.

Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to artic...

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Detalles Bibliográficos
Autores: Martínez Rodríguez, Natalia, Barona Dorado, Cristina, Martín-Arés, María, Cortés Bretón Brinkmann, Jorge, Martínez González, José María
Tipo de recurso: artículo
Fecha de publicación:2012
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/129125
Acceso en línea:https://hdl.handle.net/20.500.14352/129125
Access Level:acceso abierto
Palabra clave:615.211:616.314-089
Articaine
Lidocaine
Vasoconstrictor
Adverse reactions
Ciencias Biomédicas
Odontología (Odontología)
Medicamentos
Cirugía bucofacial
32 Ciencias Médicas
3201 Ciencias Clínicas
3209.03 Evaluación de Medicamentos
3213 Cirugía
3213.13 Ortodoncia-Estomatología
Descripción
Sumario:Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to articaine hydrochloride with epinephrine 1:100,000 and lidocaine hydrochloride with epinephrine 1:100,000. The variables analysed were latency period, duration of anaesthetic effect, tolerance and adverse reactions. Results: Both the latency period and the duration of anaesthetic effect were greater for articaine, although the differences were not statistically significant. Latency: mean difference of 2.70 ± 2.12 minutes (95%CI of -1.51 minutes - 6.92 minutes). Duration: mean difference of -33 minutes 5 seconds ± 31 minutes (95% CI -1 hour 35 minutes - 29 minutes). There were 4 adverse events that did not require the patients to be withdrawn from the study. Conclusions: The anaesthetics in this study have very similar properties for use in surgery and have demonstrated a good safety and tolerability profile.