Electroencephalographic Characterization of Sensorimotor Neural Activation During Swallowing in Dysphagic Patients
Highlights What are the main findings? EEG analysis revealed reduced beta desynchronization in motor cortical areas of post-stroke patients. Dysphagic patients showed specific deficits in alpha/beta desynchronization at C3 and Cz and exhibited abnormal lateralization. What are the implications of th...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| Repositorio: | r-FISABIO. Repositorio Institucional de Producción Científica |
| OAI Identifier: | oai:fisabio.fundanetsuite.com:p19864 |
| Acceso en línea: | https://fisabio.portalinvestigacion.com/publicaciones/19864 |
| Access Level: | acceso abierto |
| Palabra clave: | neurogenic dysphagia electroencephalography (EEG) event-related spectral perturbation (ERSP) stroke neurophysiology |
| Sumario: | Highlights What are the main findings? EEG analysis revealed reduced beta desynchronization in motor cortical areas of post-stroke patients. Dysphagic patients showed specific deficits in alpha/beta desynchronization at C3 and Cz and exhibited abnormal lateralization. What are the implications of the main findings? EEG-derived biomarkers allow objective discrimination between dysphagic and non-dysphagic populations. The accessibility of EEG supports its integration into clinical workflows for dysphagia diagnosis and follow-up.Highlights What are the main findings? EEG analysis revealed reduced beta desynchronization in motor cortical areas of post-stroke patients. Dysphagic patients showed specific deficits in alpha/beta desynchronization at C3 and Cz and exhibited abnormal lateralization. What are the implications of the main findings? EEG-derived biomarkers allow objective discrimination between dysphagic and non-dysphagic populations. The accessibility of EEG supports its integration into clinical workflows for dysphagia diagnosis and follow-up.Abstract Dysphagia is commonly assessed with qualitative and image-based diagnostic tools, which are often costly, technically demanding, and limited in their ability to support individualized rehabilitation. Electroencephalography (EEG) has recently emerged as a quantitative, cost-effective, and accessible alternative to characterize sensorimotor activity during swallowing, though its potential in dysphagic populations has not been systematically explored. This study investigated neural dynamics in 50 post-stroke dysphagic patients, 32 post-stroke non-dysphagic controls, and 21 healthy adults performing a swallowing task. EEG recordings from primary motor regions (C3, Cz, C4) were analyzed using event-related spectral perturbation (ERSP) to quantify alpha (8-13 Hz) and beta (15-30 Hz) event-related desynchronization, alongside hemispheric lateralization indices. Group comparisons revealed significantly reduced beta desynchronization in both post-stroke groups compared to healthy participants, with additional alpha and beta deficits at C3 and Cz distinguishing dysphagic patients from non-dysphagic controls. Dysphagic patients further exhibited abnormal lateralization not observed in other groups. These findings identify distinct alterations in motor cortical dynamics and hemispheric balance in dysphagia, supporting EEG-derived biomarkers as promising tools for diagnosis and clinical follow-up. The accessibility of EEG reinforces its potential integration into routine workflows to enable objective and personalized management of post-stroke dysphagia. |
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