Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers

Producción Científica

Detalles Bibliográficos
Autores: Fernández Lázaro, Diego, García Hernández, Juan Luis, Caballero García, Alberto, Córdova Martínez, Alfredo, Mielgo Ayuso, Juan Francisco, Cruz Hernández, Juan Jesús
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/52322
Acceso en línea:https://doi.org/10.3390/diagnostics10040215
https://uvadoc.uva.es/handle/10324/52322
Access Level:acceso abierto
Palabra clave:Cancer
Cáncer
Liquid biopsy
Biopsia líquida
Biofluids
Biofluidos
Tumor cells
Células tumorales
3201.01 Oncología
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oai_identifier_str oai:uvadoc.uva.es:10324/52322
network_acronym_str ES
network_name_str España
repository_id_str
spelling Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkersFernández Lázaro, DiegoGarcía Hernández, Juan LuisCaballero García, AlbertoCórdova Martínez, AlfredoMielgo Ayuso, Juan FranciscoCruz Hernández, Juan JesúsCancerCáncerLiquid biopsyBiopsia líquidaBiofluidsBiofluidosTumor cellsCélulas tumorales3201.01 OncologíaProducción CientíficaIn recent years, there has been an increase in knowledge of cancer, accompanied by a technological development that gives rise to medical oncology. An instrument that allows the implementation of individualized therapeutic strategies is the liquid biopsy. Currently, it is the most innovative methodology in medical oncology. Its high potential as a tool for screening and early detection, the possibility of assessing the patient’s condition after diagnosis and relapse, as well as the effectiveness of real-time treatments in different types of cancer. Liquid biopsy is capable of overcoming the limitations of tissue biopsies. The elements that compose the liquid biopsy are circulating tumor cells, circulating tumor nucleic acids, free of cells or contained in exosomes, microvesicle and platelets. Liquid biopsy studies are performed on various biofluids extracted in a non-invasive way, and they can be performed both from the blood and in urine, saliva or cerebrospinal fluid. The development of genotyping techniques, using the elements that make up liquid biopsy, make it possible to detect mutations, intertumoral and intratumoral heterogeneity, and provide molecular information on cancer for application in medical oncology in an individualized way in different types of tumors. Therefore, liquid biopsy has the potential to change the way medical oncology could predict the course of the disease.MDPI2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3390/diagnostics10040215https://uvadoc.uva.es/handle/10324/52322reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidIngléshttps://www.mdpi.com/2075-4418/10/4/215info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:uvadoc.uva.es:10324/523222026-06-13T12:44:47Z
dc.title.none.fl_str_mv Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
title Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
spellingShingle Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
Fernández Lázaro, Diego
Cancer
Cáncer
Liquid biopsy
Biopsia líquida
Biofluids
Biofluidos
Tumor cells
Células tumorales
3201.01 Oncología
title_short Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
title_full Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
title_fullStr Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
title_full_unstemmed Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
title_sort Liquid biopsy as novel tool in precision medicine: origins, properties, identification and clinical perspective of cancer’s biomarkers
dc.creator.none.fl_str_mv Fernández Lázaro, Diego
García Hernández, Juan Luis
Caballero García, Alberto
Córdova Martínez, Alfredo
Mielgo Ayuso, Juan Francisco
Cruz Hernández, Juan Jesús
author Fernández Lázaro, Diego
author_facet Fernández Lázaro, Diego
García Hernández, Juan Luis
Caballero García, Alberto
Córdova Martínez, Alfredo
Mielgo Ayuso, Juan Francisco
Cruz Hernández, Juan Jesús
author_role author
author2 García Hernández, Juan Luis
Caballero García, Alberto
Córdova Martínez, Alfredo
Mielgo Ayuso, Juan Francisco
Cruz Hernández, Juan Jesús
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Cancer
Cáncer
Liquid biopsy
Biopsia líquida
Biofluids
Biofluidos
Tumor cells
Células tumorales
3201.01 Oncología
topic Cancer
Cáncer
Liquid biopsy
Biopsia líquida
Biofluids
Biofluidos
Tumor cells
Células tumorales
3201.01 Oncología
description Producción Científica
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/diagnostics10040215
https://uvadoc.uva.es/handle/10324/52322
url https://doi.org/10.3390/diagnostics10040215
https://uvadoc.uva.es/handle/10324/52322
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.mdpi.com/2075-4418/10/4/215
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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