Chronic nodular prurigo

Chronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. This questionnaire study examined these issues in 406 patients with chronic nodular prurigo from 15...

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Detalles Bibliográficos
Autores: Pereira, Manuel Pedro|||0000-0001-5649-2698, Zeidler, Claudia|||0000-0002-9485-8627, Wallengren, Joanna|||0000-0003-0606-6513, Halvorsen, Jon Anders|||0000-0003-2427-9600, Weisshaar, Elke|||0000-0002-7016-0224, Garcovich, Simone|||0000-0001-8967-6688, Misery, Laurent|||0000-0001-8088-7059, Brenaut, Emilie|||0000-0002-0170-5083, Savk, Ekin|||0000-0002-9318-1378, Potekaev, Nikolay|||0000-0002-9578-5490, Lvov, Andrey|||0000-0002-3875-4030, Bobko, Svetlana|||0000-0002-4446-2368, Szepietowski, Jacek C.|||0000-0003-0766-6342, Reich, Adam|||0000-0002-5573-1754, Bożek, Agnieszka|||0000-0001-7000-1728, Legat, Franz Josef|||0000-0002-7785-4739, Metz, Martin|||0000-0002-4070-9976, Streit, Markus, Serra Baldrich, Esther|||0000-0001-7603-0300, Gonçalo, Margarida|||0000-0001-6842-1360, Storck, Michael|||0000-0002-8160-0184, Nau, Teresa, Hoffmann, Vincent, Steinke, Sabine, Greiwe, Ina, Dugas, Martin|||0000-0001-9740-0788, Augustin, Matthias|||0000-0002-4026-8728, Ständer, Sonja|||0000-0003-3612-7786
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:272121
Acceso en línea:https://ddd.uab.cat/record/272121
https://dx.doi.org/urn:doi:10.2340/00015555-3726
Access Level:acceso abierto
Palabra clave:Nodular prurigo
Chronic nodular prurigo
Patient- reported outcome
Itch
Pruritus
Therapy
Descripción
Sumario:Chronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. This questionnaire study examined these issues in 406 patients with chronic nodular prurigo from 15 European dermatological centres. Improvements in itch, skin lesions and sleep were the most important goals. Emollients, topical corticosteroids and antihistamines were the most frequently used treatments, while a minority of patients were prescribed potent medications, such as systemic immunosuppressants and gabapentinoids. Most patients were not satisfied with their previous therapy (56.8%), while 9.8% did not receive any therapy despite having active disease. A substantial number of respondents (28.7%) considered none of the therapeutic options effective. Although chronic nodular prurigo is a severe disease, most patients were not treated with potent systemic drugs, which may contribute to the high levels of dissatisfaction and disbelief in available therapies. Specific guidelines for chronic nodular prurigo and the development of novel therapies are necessary to improve care.

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