SEOM clinical guideline for the diagnosis and treatment of gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJA) (2019)

Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, it represents the sixth cause of cancer death. In Western countries, the incidence is decreasing slightly, with an increase in gastroesophageal junction adenocarc...

Full description

Bibliographic Details
Authors: Martín-Richard, Marta|||0000-0003-4933-2463, Carmona-Bayonas, Alberto|||0000-0002-1930-9660, Custodio, Ana Belén, Gallego Plazas, Javier|||0000-0002-0584-1242, Jiménez Fonseca, Paula|||0000-0003-4592-3813, Reina, Juan Jose, Richart, Paula, Rivera, Fernando|||0000-0001-8915-226X, Alsina, Maria|||0000-0003-4835-7159, Sastre Valera, Javier|||0000-0001-6538-0065
Format: article
Publication Date:2020
Country:España
Institution:Universitat Autònoma de Barcelona
Repository:Dipòsit Digital de Documents de la UAB
Language:English
OAI Identifier:oai:ddd.uab.cat:283886
Online Access:https://ddd.uab.cat/record/283886
https://dx.doi.org/urn:doi:10.1007/s12094-019-02259-9
Access Level:Open access
Keyword:Diagnosis
Gastric cancer
Gastroesophageal junction adenocarcinoma
Treatment
Description
Summary:Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, it represents the sixth cause of cancer death. In Western countries, the incidence is decreasing slightly, with an increase in gastroesophageal junction adenocarcinoma (GEJA), a different entity that we separate specifically in the guideline. Molecular biology advances have been done recently, but do not yet lead to the choice in treatment approach except in advanced disease with overexpression of HER2. Endoscopic resection in very early stage, perioperative chemotherapy in locally advanced tumors and preliminary immune therapy resulting in advanced disease are the main treatment innovations in the GC/GEJA treatment. We describe the different evidences and recommendations following the statements of the American College of Physicians.