How efficient is resveratrol as an antioxidant of the Mediterranean diet, towards alterations during the aging process?

Mediterranean diet (MD) is the most relevant nutritional aspect of the multisecular Mediterranean civilisation which includes wine as an element of health and wellbeing when consumed with moderation. Mediterranean meals provide food micronutrients which include polyphenols, especially resveratrol fr...

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Detalles Bibliográficos
Autores: Silva, Paula, Soldevila Verdeguer, Carla, Tur, Josep A, Andreoletti, Pierre, Cherkaoui-Malki, Mustapha, Latruffe, Norbert
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/22819
Acceso en línea:https://hdl.handle.net/20.500.12105/22819
Access Level:acceso abierto
Palabra clave:Aging
Antioxidant
Mediterranean diet
Resveratrol
Dieta Mediterránea
Animales
Humanos
Neoplasias
Envejecimiento Saludable
Enfermedades Cardiovasculares
Antioxidantes
Antioxidants
Cardiovascular Diseases
Healthy Aging
Animals
Diet, Mediterranean
Humans
Neoplasms
Descripción
Sumario:Mediterranean diet (MD) is the most relevant nutritional aspect of the multisecular Mediterranean civilisation which includes wine as an element of health and wellbeing when consumed with moderation. Mediterranean meals provide food micronutrients which include polyphenols, especially resveratrol from grape and red wine. MD, also called Cretan diet, has been proven to prevent diseases including cardiovascular pathologies, cancer, and to prevent aging. Interestingly, the grape and more precisely in grape skin contains the highest concentration of RSV. In consequence, red wine is the most concentrated food source of RSV found in the human diet. This review topic deals to how efficient is RSV towards alterations during the aging process; obtained from recent data of clinical trials, preclinical studies, and cell culture approach; especially RSV protecting effect on brain aging of elderly; its role on the microglial cells playing a central role in the neuro-inflammation; and in its anti-inflammatory effects on ocular diseases.