Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study

PURPOSE: Increased awareness of the importance of dietary fibre has led to increased interest in "functional" fibre components like digestion-resistant maltodextrin (RMD). This randomized, placebo-controlled, double-blind study assessed the effects of RMD in the colonic transit time (CTT)...

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Autores: Abellán Ruiz, María Salud, Barnuevo Espinosa, María Dolores, Contreras, Carlos, Luque Rubia, Antonio J., Sánchez, Francisca, Aldeguer García, Miriam, Garcia, Carlos, López Román, Francisco Javier
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universidad Católica San Antonio de Murcia (UCAM)
Repositorio:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
OAI Identifier:oai:repositorio.ucam.edu:10952/3537
Acceso en línea:http://hdl.handle.net/10952/3537
Access Level:acceso abierto
Palabra clave:Colonic transit time
Resistant maltodextrin
Soluble dietary fibre
Stool volume
Intestinal function
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spelling Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical studyAbellán Ruiz, María SaludBarnuevo Espinosa, María DoloresContreras, CarlosLuque Rubia, Antonio J.Sánchez, FranciscaAldeguer García, MiriamGarcia, CarlosLópez Román, Francisco JavierColonic transit timeResistant maltodextrinSoluble dietary fibreStool volumeIntestinal functionPURPOSE: Increased awareness of the importance of dietary fibre has led to increased interest in "functional" fibre components like digestion-resistant maltodextrin (RMD). This randomized, placebo-controlled, double-blind study assessed the effects of RMD in the colonic transit time (CTT) and defecation characteristics (frequency, stool volume and consistency). METHODS: Sixty-six healthy adult volunteers (32 men) who did not have a daily defecation habit had a 7-day run-in period before the 21-day intervention period with RMD or placebo. CTT and segmental CTT (SCTT) were assessed by a single abdominal X-ray film taken at the end of both periods after radiopaque marker ingestion. Defecation characteristics and intestinal functions were also assessed, which were self-reported by patients. Intragroup comparisons were evaluated by Student's paired t test, Bonferroni test and Chi-square test, while time comparisons by analysis of variance (ANOVA) and time-by-treatment interaction by repeated-measures ANOVA. RESULTS: Fifty-seven subjects were assessed for CTT (placebo, n = 28; RMD, n = 29). In the RMD group, the total CTT, left SCTT and rectosigmoidal SCTT decreased significantly compared to baseline (p < 0.01 each; -13.3, -4.7, -8.7 h, respectively). Significant differences between groups were observed in total CTT and left SCTT. Significant time-by-treatment interaction was observed in the RMD group for stool volume (p = 0.014), increasing 56 % compared to baseline (p < 0.01), while remained unchanged in the placebo group. Stool consistency was improved only in the RMD group (p < 0.01). No adverse effects related to study products were observed. CONCLUSIONS: The results show that RMD improved CTT, stool volume, stool consistency and some intestinal functions in a healthy population.Matsutani Chemical Industry Co., Ltd (Itami City, Hyogo, Japan)Ciencias de la AlimentaciónSpringer Science2016info:eu-repo/semantics/articlehttp://hdl.handle.net/10952/3537reponame:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murciainstname:Universidad Católica San Antonio de Murcia (UCAM)Inglésinfo:eu-repo/semantics/openAccessoai:repositorio.ucam.edu:10952/35372026-06-07T18:35:21Z
dc.title.none.fl_str_mv Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
title Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
spellingShingle Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
Abellán Ruiz, María Salud
Colonic transit time
Resistant maltodextrin
Soluble dietary fibre
Stool volume
Intestinal function
title_short Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
title_full Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
title_fullStr Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
title_full_unstemmed Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
title_sort Digestion-resistant maltodextrin effects on colonic transit time and stool weight: a randomized controlled clinical study
dc.creator.none.fl_str_mv Abellán Ruiz, María Salud
Barnuevo Espinosa, María Dolores
Contreras, Carlos
Luque Rubia, Antonio J.
Sánchez, Francisca
Aldeguer García, Miriam
Garcia, Carlos
López Román, Francisco Javier
author Abellán Ruiz, María Salud
author_facet Abellán Ruiz, María Salud
Barnuevo Espinosa, María Dolores
Contreras, Carlos
Luque Rubia, Antonio J.
Sánchez, Francisca
Aldeguer García, Miriam
Garcia, Carlos
López Román, Francisco Javier
author_role author
author2 Barnuevo Espinosa, María Dolores
Contreras, Carlos
Luque Rubia, Antonio J.
Sánchez, Francisca
Aldeguer García, Miriam
Garcia, Carlos
López Román, Francisco Javier
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Colonic transit time
Resistant maltodextrin
Soluble dietary fibre
Stool volume
Intestinal function
topic Colonic transit time
Resistant maltodextrin
Soluble dietary fibre
Stool volume
Intestinal function
description PURPOSE: Increased awareness of the importance of dietary fibre has led to increased interest in "functional" fibre components like digestion-resistant maltodextrin (RMD). This randomized, placebo-controlled, double-blind study assessed the effects of RMD in the colonic transit time (CTT) and defecation characteristics (frequency, stool volume and consistency). METHODS: Sixty-six healthy adult volunteers (32 men) who did not have a daily defecation habit had a 7-day run-in period before the 21-day intervention period with RMD or placebo. CTT and segmental CTT (SCTT) were assessed by a single abdominal X-ray film taken at the end of both periods after radiopaque marker ingestion. Defecation characteristics and intestinal functions were also assessed, which were self-reported by patients. Intragroup comparisons were evaluated by Student's paired t test, Bonferroni test and Chi-square test, while time comparisons by analysis of variance (ANOVA) and time-by-treatment interaction by repeated-measures ANOVA. RESULTS: Fifty-seven subjects were assessed for CTT (placebo, n = 28; RMD, n = 29). In the RMD group, the total CTT, left SCTT and rectosigmoidal SCTT decreased significantly compared to baseline (p < 0.01 each; -13.3, -4.7, -8.7 h, respectively). Significant differences between groups were observed in total CTT and left SCTT. Significant time-by-treatment interaction was observed in the RMD group for stool volume (p = 0.014), increasing 56 % compared to baseline (p < 0.01), while remained unchanged in the placebo group. Stool consistency was improved only in the RMD group (p < 0.01). No adverse effects related to study products were observed. CONCLUSIONS: The results show that RMD improved CTT, stool volume, stool consistency and some intestinal functions in a healthy population.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10952/3537
url http://hdl.handle.net/10952/3537
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Science
publisher.none.fl_str_mv Springer Science
dc.source.none.fl_str_mv reponame:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
instname:Universidad Católica San Antonio de Murcia (UCAM)
instname_str Universidad Católica San Antonio de Murcia (UCAM)
reponame_str RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
collection RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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