Luminescence thermometry for brain activity monitoring: A perspective

Minimally invasive monitoring of brain activity is essential not only to gain understanding on the working principles of the brain, but also for the development of new diagnostic tools. In this perspective we describe how brain thermometry could be an alternative to conventional methods (e.g., magne...

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Detalhes bibliográficos
Autores: Rodríguez Sevilla, Paloma, Marin, Riccardo, Ximendes, Erving Clayton, Rosal Rabes, Blanca del, Benayas Hernández, Antonio, Jaque García, Daniel
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/707393
Acesso em linha:http://hdl.handle.net/10486/707393
https://dx.doi.org/10.3389/fchem.2022.941861
Access Level:acceso abierto
Palavra-chave:Brain Activity
Brain Diagnosis
Luminescence Thermometry
Thermal Diagnosis
Física
Descrição
Resumo:Minimally invasive monitoring of brain activity is essential not only to gain understanding on the working principles of the brain, but also for the development of new diagnostic tools. In this perspective we describe how brain thermometry could be an alternative to conventional methods (e.g., magnetic resonance or nuclear medicine) for the acquisition of thermal images of the brain with enough spatial and temperature resolution to track brain activity in minimally perturbed animals. We focus on the latest advances in transcranial luminescence thermometry introducing a critical discussion on its advantages and shortcomings. We also anticipate the main challenges that the application of luminescent nanoparticles for brain thermometry will face in next years. With this work we aim to promote the development of near infrared luminescence for brain activity monitoring, which could also benefit other research areas dealing with the brain and its illnesses