Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.

Atherosclerosis starts early in life and progresses silently for decades. Considering atherosclerosis as a "systemic disease" invites the use of noninvasive methodologies to detect disease in various regions before symptoms appear. The PESA-(Progression of Early Subclinical Atherosclerosis...

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Detalles Bibliográficos
Autores: Ibáñez, Borja, Fernández-Ortiz, Antonio, Fernández-Friera, Leticia, García-Lunar, Inés, Andres, Vicente, Fuster, Valentin
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/15205
Acceso en línea:http://hdl.handle.net/20.500.12105/15205
Access Level:acceso abierto
Palabra clave:Arteries
Atherosclerosis
Disease Progression
Humans
Longitudinal Studies
Middle Aged
Plaque, Atherosclerotic
Tomography, X-Ray Computed
Ultrasonography
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spelling Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.Ibáñez, BorjaFernández-Ortiz, AntonioFernández-Friera, LeticiaGarcía-Lunar, InésAndres, VicenteFuster, ValentinArteriesAtherosclerosisDisease ProgressionHumansLongitudinal StudiesMiddle AgedPlaque, AtheroscleroticTomography, X-Ray ComputedUltrasonographyAtherosclerosis starts early in life and progresses silently for decades. Considering atherosclerosis as a "systemic disease" invites the use of noninvasive methodologies to detect disease in various regions before symptoms appear. The PESA-(Progression of Early Subclinical Atherosclerosis) CNIC-SANTANDER study is an ongoing prospective cohort study examining imaging, biological, and behavioral parameters associated with the presence and progression of early subclinical atherosclerosis. Between 2010 and 2014, PESA enrolled 4,184 asymptomatic middle-aged participants who undergo serial 3-yearly follow-up examinations including clinical interviews, lifestyle questionnaires, sampling, and noninvasive imaging assessment of multiterritorial subclinical atherosclerosis (carotids, iliofemorals, aorta, and coronaries). PESA tracks the trajectories of atherosclerosis and associated disorders from early stages to the transition to symptomatic phases. A joint venture between the CNIC and the Santander Bank, PESA is expected to run until at least 2029, and its significant contributions to date are presented in this review paper.ElsevierBanco SantanderFundación ProCNICInstituto de Salud Carlos IIIUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)Unión Europea. Comisión Europea. European Research Council (ERC)Ministerio de Ciencia e Innovación (España)20222022-11-2120212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12105/15205reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)InglésengEuropean Commission http://dx.doi.org/10.13039/501100000780 Horizon 2020 Framework Programme 819775open accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/152052026-06-12T12:43:37Z
dc.title.none.fl_str_mv Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
title Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
spellingShingle Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
Ibáñez, Borja
Arteries
Atherosclerosis
Disease Progression
Humans
Longitudinal Studies
Middle Aged
Plaque, Atherosclerotic
Tomography, X-Ray Computed
Ultrasonography
title_short Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
title_full Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
title_fullStr Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
title_full_unstemmed Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
title_sort Progression of Early Subclinical Atherosclerosis (PESA) Study: JACC Focus Seminar 7/8.
dc.creator.none.fl_str_mv Ibáñez, Borja
Fernández-Ortiz, Antonio
Fernández-Friera, Leticia
García-Lunar, Inés
Andres, Vicente
Fuster, Valentin
author Ibáñez, Borja
author_facet Ibáñez, Borja
Fernández-Ortiz, Antonio
Fernández-Friera, Leticia
García-Lunar, Inés
Andres, Vicente
Fuster, Valentin
author_role author
author2 Fernández-Ortiz, Antonio
Fernández-Friera, Leticia
García-Lunar, Inés
Andres, Vicente
Fuster, Valentin
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Banco Santander
Fundación ProCNIC
Instituto de Salud Carlos III
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
Unión Europea. Comisión Europea. European Research Council (ERC)
Ministerio de Ciencia e Innovación (España)

dc.subject.none.fl_str_mv Arteries
Atherosclerosis
Disease Progression
Humans
Longitudinal Studies
Middle Aged
Plaque, Atherosclerotic
Tomography, X-Ray Computed
Ultrasonography
topic Arteries
Atherosclerosis
Disease Progression
Humans
Longitudinal Studies
Middle Aged
Plaque, Atherosclerotic
Tomography, X-Ray Computed
Ultrasonography
description Atherosclerosis starts early in life and progresses silently for decades. Considering atherosclerosis as a "systemic disease" invites the use of noninvasive methodologies to detect disease in various regions before symptoms appear. The PESA-(Progression of Early Subclinical Atherosclerosis) CNIC-SANTANDER study is an ongoing prospective cohort study examining imaging, biological, and behavioral parameters associated with the presence and progression of early subclinical atherosclerosis. Between 2010 and 2014, PESA enrolled 4,184 asymptomatic middle-aged participants who undergo serial 3-yearly follow-up examinations including clinical interviews, lifestyle questionnaires, sampling, and noninvasive imaging assessment of multiterritorial subclinical atherosclerosis (carotids, iliofemorals, aorta, and coronaries). PESA tracks the trajectories of atherosclerosis and associated disorders from early stages to the transition to symptomatic phases. A joint venture between the CNIC and the Santander Bank, PESA is expected to run until at least 2029, and its significant contributions to date are presented in this review paper.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01
2021
2021-01-01
2022
2022-11-21
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/15205
url http://hdl.handle.net/20.500.12105/15205
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv European Commission http://dx.doi.org/10.13039/501100000780 Horizon 2020 Framework Programme 819775
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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