Principal component analysis (PCA) of samples profiled by small RNAseq technique
A. PCA of urine samples on the basis of normalized read counts of the known and putative novel miRNAs for the 38 samples initially processed. The red arrows indicate the outlier Control samples (C5, C6 and C7). B. PCA excluding the high outlier samples. CKD: Chronic kidney disease; PN: Pyelonephriti...
| Autores: | , , , , , , , , |
|---|---|
| Formato: | conjunto de datos |
| Fecha de publicación: | 2022 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/310603 |
| Acesso em linha: | http://hdl.handle.net/10261/310603 |
| Access Level: | acceso abierto |
| Palavra-chave: | Small RNA sequencing Regulate gene expression Nine differentially abundant Likely cellular origin Urinary mirna profiles Six additional mirnas Secreted urinary mirnas Feline urinary mirnaome Chronic kidney disease Invasive urinary biomarkers 102 da miRNAs Identified 212 miRNAs Healthy control cats Comparing control cats Shown diagnostic potential Relevant da miRNAs Invasive biomarkers Healthy cats Urinary micrornaome Seven miRNAs Detected miRNAs 13 miRNAs Eight cats Feline kidney Comparing pn Control study Pn cats Urological conditions Urological condition Ureteral obstruction Transcriptional level Time PCR Susclinical bacteriuria Quantitative real qPCR alone qPCR Putative novel Prospective case Previously identified Nearly 71 Including annotated Human nephropathies Five groups First time Coding RNAs |
| Resumo: | A. PCA of urine samples on the basis of normalized read counts of the known and putative novel miRNAs for the 38 samples initially processed. The red arrows indicate the outlier Control samples (C5, C6 and C7). B. PCA excluding the high outlier samples. CKD: Chronic kidney disease; PN: Pyelonephritis; SB/C: Subclinical bacteriuria/Cystitis; UO: Ureteral obstruction. |
|---|