Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index

A collaborative project in different areas of Spain and Portugal was designed to find out the variables that influence the mortality after discharge and develop a prognostic model adapted to the current healthcare needs of chronic patients in an internal medicine ward. Inclusion criteria were being...

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Detalhes bibliográficos
Autores: Suárez Dono, Francisco Javier, Novo Veleiro, Ignacio, Gude Sampedro, Francisco, Marinho, Ricardo, Xavier-Pires, Sara, Rocha, Diana, Araújo-Correia, João, Moreira, Cecília, Beires, Francisca, Pérez, Danay, David, Filipa, Vasco-Barreto, J., Del Corral-Beamonte, Esther, Piñeiro Fernandez, Juan Carlos, Casariego Vales, Emilio, Diez-Manglano, Jesús, Pose Reino, Antonio
Formato: artículo
Fecha de publicación:2023
País:España
Recursos:Servizo Galego de Saúde (SERGAS)
Repositorio:RUNA. Repositorio da Consellería de Sanidade e Sergas
OAI Identifier:oai:runa.sergas.gal:20.500.11940/21164
Acesso em linha:https://portalcientifico.sergas.gal//documentos/6613969727fb141b3b9b2743
http://hdl.handle.net/20.500.11940/21164
Access Level:acceso abierto
Palavra-chave:Female
Humans
Male
Aged
Atrial Fibrillation
Reproducibility of Results
Prospective Studies
Prognosis
Hospitalization
Neoplasms
AS Santiago
CHUS
AS Lugo
CHULA
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oai_identifier_str oai:runa.sergas.gal:20.500.11940/21164
network_acronym_str ES
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repository_id_str
spelling Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA indexSuárez Dono, Francisco JavierNovo Veleiro, IgnacioGude Sampedro, FranciscoMarinho, RicardoXavier-Pires, SaraRocha, DianaAraújo-Correia, JoãoMoreira, CecíliaBeires, FranciscaPérez, DanayDavid, FilipaVasco-Barreto, J.Del Corral-Beamonte, EstherPiñeiro Fernandez, Juan CarlosCasariego Vales, EmilioDiez-Manglano, JesúsPose Reino, AntonioFemaleHumansMaleAgedAtrial FibrillationReproducibility of ResultsProspective StudiesPrognosisHospitalizationNeoplasmsAS SantiagoCHUSAS SantiagoCHUSAS SantiagoCHUSAS LugoCHULAAS LugoCHULAAS SantiagoCHUSA collaborative project in different areas of Spain and Portugal was designed to find out the variables that influence the mortality after discharge and develop a prognostic model adapted to the current healthcare needs of chronic patients in an internal medicine ward. Inclusion criteria were being admitted to an Internal Medicine department and at least one chronic disease. Patients' physical dependence was measured through Barthel index (BI). Pfeiffer test (PT) was used to establish cognitive status. We conducted logistic regression and Cox proportional hazard models to analyze the influence of those variables on one-year mortality. We also developed an external validation once decided the variables included in the index. We enrolled 1406 patients. Mean age was 79.5 (SD = 11.5) and females were 56.5%. After the follow-up period, 514 patients (36.6%) died. Five variables were identified as significantly associated with 1 year mortality: age, being male, lower BI punctuation, neoplasia and atrial fibrillation. A model with such variables was created to estimate one-year mortality risk, leading to the CHRONIBERIA. A ROC curve was made to determine the reliability of this index when applied to the global sample. An AUC of 0.72 (0.7-0.75) was obtained. The external validation of the index was successful and showed an AUC of 0.73 (0.67-0.79). Atrial fibrillation along with an advanced age, being male, low BI score, or an active neoplasia in chronic patients could be critical to identify high risk multiple chronic conditions patients. Together, these variables constitute the new CHRONIBERIA index.2023info:eu-repo/semantics/articlehttps://portalcientifico.sergas.gal//documentos/6613969727fb141b3b9b2743http://hdl.handle.net/20.500.11940/21164reponame:RUNA. Repositorio da Consellería de Sanidade e Sergasinstname:Servizo Galego de Saúde (SERGAS)Ingléshttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:runa.sergas.gal:20.500.11940/211642026-06-12T08:40:47Z
dc.title.none.fl_str_mv Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
title Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
spellingShingle Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
Suárez Dono, Francisco Javier
Female
Humans
Male
Aged
Atrial Fibrillation
Reproducibility of Results
Prospective Studies
Prognosis
Hospitalization
Neoplasms
AS Santiago
CHUS
AS Santiago
CHUS
AS Santiago
CHUS
AS Lugo
CHULA
AS Lugo
CHULA
AS Santiago
CHUS
title_short Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
title_full Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
title_fullStr Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
title_full_unstemmed Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
title_sort Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
dc.creator.none.fl_str_mv Suárez Dono, Francisco Javier
Novo Veleiro, Ignacio
Gude Sampedro, Francisco
Marinho, Ricardo
Xavier-Pires, Sara
Rocha, Diana
Araújo-Correia, João
Moreira, Cecília
Beires, Francisca
Pérez, Danay
David, Filipa
Vasco-Barreto, J.
Del Corral-Beamonte, Esther
Piñeiro Fernandez, Juan Carlos
Casariego Vales, Emilio
Diez-Manglano, Jesús
Pose Reino, Antonio
author Suárez Dono, Francisco Javier
author_facet Suárez Dono, Francisco Javier
Novo Veleiro, Ignacio
Gude Sampedro, Francisco
Marinho, Ricardo
Xavier-Pires, Sara
Rocha, Diana
Araújo-Correia, João
Moreira, Cecília
Beires, Francisca
Pérez, Danay
David, Filipa
Vasco-Barreto, J.
Del Corral-Beamonte, Esther
Piñeiro Fernandez, Juan Carlos
Casariego Vales, Emilio
Diez-Manglano, Jesús
Pose Reino, Antonio
author_role author
author2 Novo Veleiro, Ignacio
Gude Sampedro, Francisco
Marinho, Ricardo
Xavier-Pires, Sara
Rocha, Diana
Araújo-Correia, João
Moreira, Cecília
Beires, Francisca
Pérez, Danay
David, Filipa
Vasco-Barreto, J.
Del Corral-Beamonte, Esther
Piñeiro Fernandez, Juan Carlos
Casariego Vales, Emilio
Diez-Manglano, Jesús
Pose Reino, Antonio
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Female
Humans
Male
Aged
Atrial Fibrillation
Reproducibility of Results
Prospective Studies
Prognosis
Hospitalization
Neoplasms
AS Santiago
CHUS
AS Santiago
CHUS
AS Santiago
CHUS
AS Lugo
CHULA
AS Lugo
CHULA
AS Santiago
CHUS
topic Female
Humans
Male
Aged
Atrial Fibrillation
Reproducibility of Results
Prospective Studies
Prognosis
Hospitalization
Neoplasms
AS Santiago
CHUS
AS Santiago
CHUS
AS Santiago
CHUS
AS Lugo
CHULA
AS Lugo
CHULA
AS Santiago
CHUS
description A collaborative project in different areas of Spain and Portugal was designed to find out the variables that influence the mortality after discharge and develop a prognostic model adapted to the current healthcare needs of chronic patients in an internal medicine ward. Inclusion criteria were being admitted to an Internal Medicine department and at least one chronic disease. Patients' physical dependence was measured through Barthel index (BI). Pfeiffer test (PT) was used to establish cognitive status. We conducted logistic regression and Cox proportional hazard models to analyze the influence of those variables on one-year mortality. We also developed an external validation once decided the variables included in the index. We enrolled 1406 patients. Mean age was 79.5 (SD = 11.5) and females were 56.5%. After the follow-up period, 514 patients (36.6%) died. Five variables were identified as significantly associated with 1 year mortality: age, being male, lower BI punctuation, neoplasia and atrial fibrillation. A model with such variables was created to estimate one-year mortality risk, leading to the CHRONIBERIA. A ROC curve was made to determine the reliability of this index when applied to the global sample. An AUC of 0.72 (0.7-0.75) was obtained. The external validation of the index was successful and showed an AUC of 0.73 (0.67-0.79). Atrial fibrillation along with an advanced age, being male, low BI score, or an active neoplasia in chronic patients could be critical to identify high risk multiple chronic conditions patients. Together, these variables constitute the new CHRONIBERIA index.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://portalcientifico.sergas.gal//documentos/6613969727fb141b3b9b2743
http://hdl.handle.net/20.500.11940/21164
url https://portalcientifico.sergas.gal//documentos/6613969727fb141b3b9b2743
http://hdl.handle.net/20.500.11940/21164
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:RUNA. Repositorio da Consellería de Sanidade e Sergas
instname:Servizo Galego de Saúde (SERGAS)
instname_str Servizo Galego de Saúde (SERGAS)
reponame_str RUNA. Repositorio da Consellería de Sanidade e Sergas
collection RUNA. Repositorio da Consellería de Sanidade e Sergas
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.811543

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