Home sleep testing to direct upper airway stimulation therapy optimization for sleep apnea

Objectives/hypothesis: Selective upper airway stimulation (sUAS) is a well-established treatment option for obstructive sleep apnea (OSA). This study aimed to determine if there are benefits in performing a home sleep test (HST) to evaluate postoperative sUAS effectiveness after patient acclimatizat...

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Detalles Bibliográficos
Autores: Steffen, A. (Armin)|||/items/c059a7f2-964b-45a7-a880-be56c35ac6d9, König, I.R. (Inke R.)|||/items/0fb09982-4d73-4384-b6d3-b78ea3153445, Baptista-Jardin, P.M. (Peter Michael)|||/items/66ecbc41-d708-4b43-a527-b733813d5195, Abrams, N. (Nils)|||/items/80114691-0966-463b-b708-8a0cf56abf9e, Jeschke, S. (Stephanie)|||/items/39d0edf8-0bb5-4312-9d7b-602e3303fe2f, Hasselbacher, K. (Katrin)|||/items/cad4741d-99f7-4829-8f41-6286da360a17
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/115312
Acceso en línea:https://hdl.handle.net/10171/115312
Access Level:acceso abierto
Palabra clave:Obstructive sleep apnea
Hypoglossal nerve stimulation
Positive airway pressure failure
Sleep surgery
Upper airway stimulation
Descripción
Sumario:Objectives/hypothesis: Selective upper airway stimulation (sUAS) is a well-established treatment option for obstructive sleep apnea (OSA). This study aimed to determine if there are benefits in performing a home sleep test (HST) to evaluate postoperative sUAS effectiveness after patient acclimatization compared to the generally used polysomnography (PSG) titration, as measured by long-term follow-up outcomes. Study design: Retrospective comparative cohort analysis. Methods: We conducted an analysis of consecutive patients at our center who had completed a 6-month follow-up (month 6 [M6]) and recorded data from M6, month 12 (M12), and month 24 (M24). After device activation, we performed an HST with the patient's stimulation settings, and measured the apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS), and device usage. These values were compared to patients who had undergone PSG-based device titration. Results: Baseline values of the initial 131 patients show high ESS and moderate OSA. At the 2-month time point of the HST, nearly half of the patients (46.2%) reached an AHI ≤15/hr, and approximately a fifth (19.2%) reached <5/hr. The PSG and HST groups differed in median ESS at M24, but no other differences were observed for ESS at M6 and M12. Both groups showed similar AHI, oxygen desaturation, and usage hours per week. Conclusions: Adjusting therapy by using the HST technique after device activation and acclimatization has clinical and economic advantages. These advantages are contingent on several conditions being met when deviating from the standard device protocol, including precise communication with the referring sleep medicine physicians, especially their role in helping with long-term follow-up. Level of evidence: 4 Laryngoscope, 131:E1375-E1379, 2021.