TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction

This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structural...

Descripción completa

Detalles Bibliográficos
Autores: Chang, Jia-Ming, 1978-, Di Tommaso, Paolo, Lefort, Vincent, Gascuel, Olivier, Notredame, Cedric
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/25135
Acceso en línea:http://hdl.handle.net/10230/25135
http://dx.doi.org/10.1093/nar/gkv310
Access Level:acceso abierto
Palabra clave:Servidors web
Filogènia
id ES_706e913dfc2a3bbf8d2804bcbe23b67a
oai_identifier_str oai:recercat.cat:10230/25135
network_acronym_str ES
network_name_str España
repository_id_str
spelling TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstructionChang, Jia-Ming, 1978-Di Tommaso, PaoloLefort, VincentGascuel, OlivierNotredame, CedricServidors webFilogèniaThis article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structurally analogous residues and also most likely to support an accurate phylogenetic reconstruction. The TCS scoring scheme has been shown to be accurate predictor of structural alignment correctness among commonly used methods. It has also been shown to outperform common filtering schemes like Gblocks or trimAl when doing MSA post-processing prior to phylogenetic tree reconstruction. The web server is available from http://tcoffee.crg.cat/tcs.Oxford University Press201520152015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/25135http://dx.doi.org/10.1093/nar/gkv310reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésNucleic acids research. 2015;43(W1):W3-W6© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/251352026-05-29T05:05:01Z
dc.title.none.fl_str_mv TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
title TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
spellingShingle TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
Chang, Jia-Ming, 1978-
Servidors web
Filogènia
title_short TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
title_full TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
title_fullStr TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
title_full_unstemmed TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
title_sort TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
dc.creator.none.fl_str_mv Chang, Jia-Ming, 1978-
Di Tommaso, Paolo
Lefort, Vincent
Gascuel, Olivier
Notredame, Cedric
author Chang, Jia-Ming, 1978-
author_facet Chang, Jia-Ming, 1978-
Di Tommaso, Paolo
Lefort, Vincent
Gascuel, Olivier
Notredame, Cedric
author_role author
author2 Di Tommaso, Paolo
Lefort, Vincent
Gascuel, Olivier
Notredame, Cedric
author2_role author
author
author
author
dc.subject.none.fl_str_mv Servidors web
Filogènia
topic Servidors web
Filogènia
description This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structurally analogous residues and also most likely to support an accurate phylogenetic reconstruction. The TCS scoring scheme has been shown to be accurate predictor of structural alignment correctness among commonly used methods. It has also been shown to outperform common filtering schemes like Gblocks or trimAl when doing MSA post-processing prior to phylogenetic tree reconstruction. The web server is available from http://tcoffee.crg.cat/tcs.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/25135
http://dx.doi.org/10.1093/nar/gkv310
url http://hdl.handle.net/10230/25135
http://dx.doi.org/10.1093/nar/gkv310
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Nucleic acids research. 2015;43(W1):W3-W6
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869410580234764288
score 15,81155

Similares en LA Referencia