Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals
<p>Background: The Monachinae, or southern seals, are one of two subfamilies within the Phocidae and are home</p><p>to iconic pinnipeds such as the leopard seal, a fierce Antarctic top predator, and the Mediterranean monk seal, one</p><p>of the world’s most endangered m...
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/227917 |
| Acceso en línea: | https://hdl.handle.net/2445/227917 |
| Access Level: | acceso abierto |
| Palabra clave: | Genomes ADN mitocondrial Foques Pinnípedes Mitochondrial DNA Seals (Animals) Pinnipedia |
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Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern sealsNebenführ, MarcelHamadou, Alexander BenAguilar, ÀlexBorrell Thió, AssumpcióGkafas, Georgios A.Janke, AxelGenomesADN mitocondrialFoquesPinnípedesGenomesMitochondrial DNASeals (Animals)Pinnipedia<p>Background: The Monachinae, or southern seals, are one of two subfamilies within the Phocidae and are home</p><p>to iconic pinnipeds such as the leopard seal, a fierce Antarctic top predator, and the Mediterranean monk seal, one</p><p>of the world’s most endangered mammals. These two species are difficult to study and sample, due to their hidden</p><p>lives in extreme environments or, in case of the monk seal, their critically reduced population sizes; consequently,</p><p>genetic data from these two species is scarce. However, cost developments and advances in genome sequencing</p><p>have made it possible to generate continuous genome assemblies from DNA of even stranded individuals, allowing</p><p>to assemble the first reference genomes of such rarely observed species.</p><p>Results: In this study, we have sequenced the genomes of the leopard seal and the Mediterranean monk seal using</p><p>PacBio’s CCS technology to assemble the very first genomes for these species. Four additional Mediterranean monk</p><p>seal individuals were sequenced using Illumina short-read technology. These data allowed analysis of their demography</p><p>and genomic diversity based on whole-genome data, confirming low genetic variability and small numbers</p><p>of individuals for the Mauritanian population of the Mediterranean monk seal. In contrast, the relatively abundant</p><p>leopard seal shows a high degree of heterozygosity, comparable in the range of other common carnivores.</p><p>Conclusions: The first genome assemblies for these seals will lay the groundwork for population-level and other studies</p><p>to better understand their evolutionary history and biology and to aid conservation efforts.</p>BioMed Central2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/227917Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1186/s12915-025-02207-wBMC Biology, 2025, vol. 23, num.102https://doi.org/10.1186/s12915-025-02207-wcc-by (c) Nebenführ, M. et al., 2025http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/2279172026-05-27T06:46:51Z |
| dc.title.none.fl_str_mv |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| title |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| spellingShingle |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals Nebenführ, Marcel Genomes ADN mitocondrial Foques Pinnípedes Genomes Mitochondrial DNA Seals (Animals) Pinnipedia |
| title_short |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| title_full |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| title_fullStr |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| title_full_unstemmed |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| title_sort |
Mediterranean monk seal (Monachus monachus) and leopard seal (Hydrurga leptonyx) de novo genomes to study the demographic history and genetic diversity of southern seals |
| dc.creator.none.fl_str_mv |
Nebenführ, Marcel Hamadou, Alexander Ben Aguilar, Àlex Borrell Thió, Assumpció Gkafas, Georgios A. Janke, Axel |
| author |
Nebenführ, Marcel |
| author_facet |
Nebenführ, Marcel Hamadou, Alexander Ben Aguilar, Àlex Borrell Thió, Assumpció Gkafas, Georgios A. Janke, Axel |
| author_role |
author |
| author2 |
Hamadou, Alexander Ben Aguilar, Àlex Borrell Thió, Assumpció Gkafas, Georgios A. Janke, Axel |
| author2_role |
author author author author author |
| dc.subject.none.fl_str_mv |
Genomes ADN mitocondrial Foques Pinnípedes Genomes Mitochondrial DNA Seals (Animals) Pinnipedia |
| topic |
Genomes ADN mitocondrial Foques Pinnípedes Genomes Mitochondrial DNA Seals (Animals) Pinnipedia |
| description |
<p>Background: The Monachinae, or southern seals, are one of two subfamilies within the Phocidae and are home</p><p>to iconic pinnipeds such as the leopard seal, a fierce Antarctic top predator, and the Mediterranean monk seal, one</p><p>of the world’s most endangered mammals. These two species are difficult to study and sample, due to their hidden</p><p>lives in extreme environments or, in case of the monk seal, their critically reduced population sizes; consequently,</p><p>genetic data from these two species is scarce. However, cost developments and advances in genome sequencing</p><p>have made it possible to generate continuous genome assemblies from DNA of even stranded individuals, allowing</p><p>to assemble the first reference genomes of such rarely observed species.</p><p>Results: In this study, we have sequenced the genomes of the leopard seal and the Mediterranean monk seal using</p><p>PacBio’s CCS technology to assemble the very first genomes for these species. Four additional Mediterranean monk</p><p>seal individuals were sequenced using Illumina short-read technology. These data allowed analysis of their demography</p><p>and genomic diversity based on whole-genome data, confirming low genetic variability and small numbers</p><p>of individuals for the Mauritanian population of the Mediterranean monk seal. In contrast, the relatively abundant</p><p>leopard seal shows a high degree of heterozygosity, comparable in the range of other common carnivores.</p><p>Conclusions: The first genome assemblies for these seals will lay the groundwork for population-level and other studies</p><p>to better understand their evolutionary history and biology and to aid conservation efforts.</p> |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/2445/227917 |
| url |
https://hdl.handle.net/2445/227917 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Reproducció del document publicat a: https://doi.org/10.1186/s12915-025-02207-w BMC Biology, 2025, vol. 23, num.102 https://doi.org/10.1186/s12915-025-02207-w |
| dc.rights.none.fl_str_mv |
cc-by (c) Nebenführ, M. et al., 2025 http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
cc-by (c) Nebenführ, M. et al., 2025 http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
BioMed Central |
| publisher.none.fl_str_mv |
BioMed Central |
| dc.source.none.fl_str_mv |
Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona |
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Universidad de Barcelona |
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Dipòsit Digital de la UB |
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Dipòsit Digital de la UB |
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