Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine

Environmental insults, such as exposure to pathogens, modulate the behavioural coping style of animals to stressors, and repeated exposure to stressful environments may lead to species-specific infection phenotypes. To analyse the influence of stress behavioural phenotypes on immune and metabolic pe...

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Autores: Vargas, Reynaldo, Balasch Alemany, Joan Carles|||0000-0002-0771-3746, Brandts, Irene|||0000-0002-7372-8639, Reyes Lopez, Felipe Esteban|||0000-0002-5001-457X, Tort Bardolet, Lluís|||0000-0002-3907-722X, Teles, Mariana|||0000-0001-5525-4049
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:253736
Acceso en línea:https://ddd.uab.cat/record/253736
https://dx.doi.org/urn:doi:10.1038/s41598-018-35863-w
Access Level:acceso abierto
Palabra clave:Vibrio anguillarum
Bath vaccination
Total oxidant status
Metabolic endpoints
Higher metabolic response
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spelling Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccineVargas, ReynaldoBalasch Alemany, Joan Carles|||0000-0002-0771-3746Brandts, Irene|||0000-0002-7372-8639Reyes Lopez, Felipe Esteban|||0000-0002-5001-457XTort Bardolet, Lluís|||0000-0002-3907-722XTeles, Mariana|||0000-0001-5525-4049Vibrio anguillarumBath vaccinationTotal oxidant statusMetabolic endpointsHigher metabolic responseEnvironmental insults, such as exposure to pathogens, modulate the behavioural coping style of animals to stressors, and repeated exposure to stressful environments may lead to species-specific infection phenotypes. To analyse the influence of stress behavioural phenotypes on immune and metabolic performance, gilthead sea bream (Sparus aurata L.) were first screened for proactive and reactive coping styles. Once characterized, both behavioural phenotypes fish groups were bath vaccinated with bacterin from Vibrio anguillarum, an opportunistic widespread pathogen of fish. Gills and liver were sampled at 0 (control group), 1, 3 and 7 days post-vaccination. Immune-, oxidative stress- and metabolic-related transcripts (il1β, tnfα, igm, gpx1, sod, cat, lpl, ghr1 and ghr2), metabolic endpoints (glucose, cholesterol and triglycerides), hepatic health indicators (aspartate aminotransferase, alanine transaminase and alkaline phosphatase), oxidative stress status (esterase activity, total antioxidant capacity and total oxidative status) and stress biomarkers (cortisol) were determined. Present results indicate that screening for coping styles in the gilthead sea bream segregated the two distinct phenotypes as expected: proactive and reactive. Results also indicate that under bath vaccination proactive fish show high immune response and lower metabolism, whereas reactive fish show low immune and higher metabolic responses. 22018-01-0120182018-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/253736https://dx.doi.org/urn:doi:10.1038/s41598-018-35863-wreponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengAgencia Estatal de Investigación https://doi.org/10.13039/501100011033 AGL2016-76069-C2-2-RMinisterio de Ciencia e Innovación https://doi.org/10.13039/501100004837 AGL2016-81808-REDTopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2537362026-06-06T12:50:31Z
dc.title.none.fl_str_mv Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
title Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
spellingShingle Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
Vargas, Reynaldo
Vibrio anguillarum
Bath vaccination
Total oxidant status
Metabolic endpoints
Higher metabolic response
title_short Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
title_full Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
title_fullStr Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
title_full_unstemmed Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
title_sort Variations in the immune and metabolic response of proactive and reactive Sparus aurata under stimulation with Vibrio anguillarum vaccine
dc.creator.none.fl_str_mv Vargas, Reynaldo
Balasch Alemany, Joan Carles|||0000-0002-0771-3746
Brandts, Irene|||0000-0002-7372-8639
Reyes Lopez, Felipe Esteban|||0000-0002-5001-457X
Tort Bardolet, Lluís|||0000-0002-3907-722X
Teles, Mariana|||0000-0001-5525-4049
author Vargas, Reynaldo
author_facet Vargas, Reynaldo
Balasch Alemany, Joan Carles|||0000-0002-0771-3746
Brandts, Irene|||0000-0002-7372-8639
Reyes Lopez, Felipe Esteban|||0000-0002-5001-457X
Tort Bardolet, Lluís|||0000-0002-3907-722X
Teles, Mariana|||0000-0001-5525-4049
author_role author
author2 Balasch Alemany, Joan Carles|||0000-0002-0771-3746
Brandts, Irene|||0000-0002-7372-8639
Reyes Lopez, Felipe Esteban|||0000-0002-5001-457X
Tort Bardolet, Lluís|||0000-0002-3907-722X
Teles, Mariana|||0000-0001-5525-4049
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Vibrio anguillarum
Bath vaccination
Total oxidant status
Metabolic endpoints
Higher metabolic response
topic Vibrio anguillarum
Bath vaccination
Total oxidant status
Metabolic endpoints
Higher metabolic response
description Environmental insults, such as exposure to pathogens, modulate the behavioural coping style of animals to stressors, and repeated exposure to stressful environments may lead to species-specific infection phenotypes. To analyse the influence of stress behavioural phenotypes on immune and metabolic performance, gilthead sea bream (Sparus aurata L.) were first screened for proactive and reactive coping styles. Once characterized, both behavioural phenotypes fish groups were bath vaccinated with bacterin from Vibrio anguillarum, an opportunistic widespread pathogen of fish. Gills and liver were sampled at 0 (control group), 1, 3 and 7 days post-vaccination. Immune-, oxidative stress- and metabolic-related transcripts (il1β, tnfα, igm, gpx1, sod, cat, lpl, ghr1 and ghr2), metabolic endpoints (glucose, cholesterol and triglycerides), hepatic health indicators (aspartate aminotransferase, alanine transaminase and alkaline phosphatase), oxidative stress status (esterase activity, total antioxidant capacity and total oxidative status) and stress biomarkers (cortisol) were determined. Present results indicate that screening for coping styles in the gilthead sea bream segregated the two distinct phenotypes as expected: proactive and reactive. Results also indicate that under bath vaccination proactive fish show high immune response and lower metabolism, whereas reactive fish show low immune and higher metabolic responses.
publishDate 2018
dc.date.none.fl_str_mv 2
2018-01-01
2018
2018-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/253736
https://dx.doi.org/urn:doi:10.1038/s41598-018-35863-w
url https://ddd.uab.cat/record/253736
https://dx.doi.org/urn:doi:10.1038/s41598-018-35863-w
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 AGL2016-76069-C2-2-R
Ministerio de Ciencia e Innovación https://doi.org/10.13039/501100004837 AGL2016-81808-REDT
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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repository.mail.fl_str_mv
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