HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography

Abstract: Time-of-Flight positron emission tomography scanners demand fast and efficient photo sensors and scintillators coupled to fast readout electronics. This article presents the high resolution flexible Time-over-Threshold (HRFlexToT), a 16-channel application-specific-integrated circuit for s...

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Autores: Sánchez, David, Gómez, Sergio, Mauricio Ferré, Joan, Freixas, Lluis, Sanuy Charles, Andreu, Guixé, Gerard, López, Albert, Manera Escalero, Rafel, Marín, Jesús, Pérez, José.M., Picatoste Olloqui, Eduardo, Pujol, Carolina, Sanmukh, Anand, Rato, Pedro, Vela, Óscar, Gascón Fora, David
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2022
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/214176
Acesso em linha:https://hdl.handle.net/2445/214176
Access Level:acceso abierto
Palavra-chave:Tomografia per emissió de positrons
Fotoelectroquímica
Positron emission tomography
Photoelectrochemistry
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spelling HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission TomographySánchez, DavidGómez, SergioMauricio Ferré, JoanFreixas, LluisSanuy Charles, AndreuGuixé, GerardLópez, AlbertManera Escalero, RafelMarín, JesúsPérez, José.M.Picatoste Olloqui, EduardoPujol, CarolinaSanmukh, AnandRato, PedroVela, ÓscarGascón Fora, DavidTomografia per emissió de positronsFotoelectroquímicaPositron emission tomographyPhotoelectrochemistryAbstract: Time-of-Flight positron emission tomography scanners demand fast and efficient photo sensors and scintillators coupled to fast readout electronics. This article presents the high resolution flexible Time-over-Threshold (HRFlexToT), a 16-channel application-specific-integrated circuit for silicon photomultipliers (SiPM) anode readout manufactured using XFAB 0.18- μm CMOS technology. The main features of the HRFlexToT are a linear Time-over-Threshold with an extended dynamic range (10 bits) for energy measurement, low power consumption (≈ 3.5 mW/ch), and an excellent timing response. The experimental measurements show an energy linearity error of ≈ 3% and an energy resolution of about 12% at 511 keV. Single-photon time resolution measurements performed using an Fondazione Bruno Kessler (FBK) SiPM NUV-HD ( 4×4 mm2 pixel, 40- μm cell) and a Hamamatsu SiPM S13360-3050CS are around 142 and 167 ps full width at half maximum (FWHM), respectively. Coincidence time resolution (CTR) measurements with small cross-section pixelated crystals (LSO:Ce,Ca 0.4%, 2×2×5 mm3) coupled to the same Hamamatsu S13360-3050CS and FBK NUV-HD sensors yield a CTR of 117 ps and 119 ps, respectively. Measurements performed with a large cross-section monolithic crystal (LFS crystal measuring 25×25×20 mm3) and a Hamamatsu SiPM array S13361-6050NE-04 show a CTR of 324 ps FWHM after time-walk and time-skew correction.Institute of Electrical and Electronics Engineers (IEEE)2024202420222024info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion17 p.application/pdfhttps://hdl.handle.net/2445/214176Articles publicats en revistes (Física Quàntica i Astrofísica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1109/TRPMS.2021.3066426IEEE Transactions on Radiation and Plasma Medical Sciences, 2022, vol. 6, num.1, p. 51-67https://doi.org/10.1109/TRPMS.2021.3066426(c) Institute of Electrical and Electronics Engineers (IEEE), 2022info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2141762026-05-29T05:05:01Z
dc.title.none.fl_str_mv HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
title HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
spellingShingle HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
Sánchez, David
Tomografia per emissió de positrons
Fotoelectroquímica
Positron emission tomography
Photoelectrochemistry
title_short HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
title_full HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
title_fullStr HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
title_full_unstemmed HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
title_sort HRFlexToT: A High Dynamic Range ASIC for Time-of-Flight Positron Emission Tomography
dc.creator.none.fl_str_mv Sánchez, David
Gómez, Sergio
Mauricio Ferré, Joan
Freixas, Lluis
Sanuy Charles, Andreu
Guixé, Gerard
López, Albert
Manera Escalero, Rafel
Marín, Jesús
Pérez, José.M.
Picatoste Olloqui, Eduardo
Pujol, Carolina
Sanmukh, Anand
Rato, Pedro
Vela, Óscar
Gascón Fora, David
author Sánchez, David
author_facet Sánchez, David
Gómez, Sergio
Mauricio Ferré, Joan
Freixas, Lluis
Sanuy Charles, Andreu
Guixé, Gerard
López, Albert
Manera Escalero, Rafel
Marín, Jesús
Pérez, José.M.
Picatoste Olloqui, Eduardo
Pujol, Carolina
Sanmukh, Anand
Rato, Pedro
Vela, Óscar
Gascón Fora, David
author_role author
author2 Gómez, Sergio
Mauricio Ferré, Joan
Freixas, Lluis
Sanuy Charles, Andreu
Guixé, Gerard
López, Albert
Manera Escalero, Rafel
Marín, Jesús
Pérez, José.M.
Picatoste Olloqui, Eduardo
Pujol, Carolina
Sanmukh, Anand
Rato, Pedro
Vela, Óscar
Gascón Fora, David
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Tomografia per emissió de positrons
Fotoelectroquímica
Positron emission tomography
Photoelectrochemistry
topic Tomografia per emissió de positrons
Fotoelectroquímica
Positron emission tomography
Photoelectrochemistry
description Abstract: Time-of-Flight positron emission tomography scanners demand fast and efficient photo sensors and scintillators coupled to fast readout electronics. This article presents the high resolution flexible Time-over-Threshold (HRFlexToT), a 16-channel application-specific-integrated circuit for silicon photomultipliers (SiPM) anode readout manufactured using XFAB 0.18- μm CMOS technology. The main features of the HRFlexToT are a linear Time-over-Threshold with an extended dynamic range (10 bits) for energy measurement, low power consumption (≈ 3.5 mW/ch), and an excellent timing response. The experimental measurements show an energy linearity error of ≈ 3% and an energy resolution of about 12% at 511 keV. Single-photon time resolution measurements performed using an Fondazione Bruno Kessler (FBK) SiPM NUV-HD ( 4×4 mm2 pixel, 40- μm cell) and a Hamamatsu SiPM S13360-3050CS are around 142 and 167 ps full width at half maximum (FWHM), respectively. Coincidence time resolution (CTR) measurements with small cross-section pixelated crystals (LSO:Ce,Ca 0.4%, 2×2×5 mm3) coupled to the same Hamamatsu S13360-3050CS and FBK NUV-HD sensors yield a CTR of 117 ps and 119 ps, respectively. Measurements performed with a large cross-section monolithic crystal (LFS crystal measuring 25×25×20 mm3) and a Hamamatsu SiPM array S13361-6050NE-04 show a CTR of 324 ps FWHM after time-walk and time-skew correction.
publishDate 2022
dc.date.none.fl_str_mv 2022
2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/214176
url https://hdl.handle.net/2445/214176
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1109/TRPMS.2021.3066426
IEEE Transactions on Radiation and Plasma Medical Sciences, 2022, vol. 6, num.1, p. 51-67
https://doi.org/10.1109/TRPMS.2021.3066426
dc.rights.none.fl_str_mv (c) Institute of Electrical and Electronics Engineers (IEEE), 2022
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Institute of Electrical and Electronics Engineers (IEEE), 2022
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 17 p.
application/pdf
dc.publisher.none.fl_str_mv Institute of Electrical and Electronics Engineers (IEEE)
publisher.none.fl_str_mv Institute of Electrical and Electronics Engineers (IEEE)
dc.source.none.fl_str_mv Articles publicats en revistes (Física Quàntica i Astrofísica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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