Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows

Tesis Doctoral inédita cotutelada por la Universidade Federal de Alagoas de Brasil y la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Física de Materiales. Fecha de lectura: 17-12-2018

Detalles Bibliográficos
Autor: Ximendes, Erving Clayton
Tipo de recurso: tesis doctoral
Fecha de publicación:2018
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/686546
Acceso en línea:http://hdl.handle.net/10486/686546
Access Level:acceso abierto
Palabra clave:Nanotecnología - Tesis doctorales
Nanopartículas - Tesis doctorales
Física
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spelling Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windowsXimendes, Erving ClaytonNanotecnología - Tesis doctoralesNanopartículas - Tesis doctoralesFísicaTesis Doctoral inédita cotutelada por la Universidade Federal de Alagoas de Brasil y la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Física de Materiales. Fecha de lectura: 17-12-2018In this thesis, the use of core/shell engineering for the synthesis of fluorescent nanoparticles (NPs) capable of operating as nanothermometers, nanoheaters and/or contrast agents for fluorescence imaging in small animal models is explored. The materials here studied – rare-earth (Nd3+, Yb3+, Tm3+ and/or Er3+) doped NPs and PbS/CdS/ZnS quantum dots (QDs) – presented emission and/or excitation bands in the so-called biological windows, where light penetration into tissues is maximal, allowing for ex vivo and in vivo applications. It was demonstrated that the spatial separation between the rare-earth ions, achieved by the core/shell nano-engineering, resulted not only in a considerable improvement on the values of thermo-optical parameters such as the light-heat conversion efficiency and the relative thermal sensitivity, but also on a multi-functionality of the nanosystems. As a consequence, innovative applications in nanothermometry were successfully accomplished when developing this thesis. Among those applications, one can mention: the study in real time of the thermal dynamics of an in vivo tissue, the detection and monitoring of cardiovascular diseases and the recording of in vivo thermal images and videos at a subcutaneous level by means of a ratiometric approach. The results here presented open up avenues for new diagnosis and control techniques that can revolutionize the current methods found in biomedicineJaque García, DanielSilva, Carlos Jacinto daDepartamento de Física de MaterialesFacultad de Ciencias20182018-12-17doctoral thesishttp://purl.org/coar/resource_type/c_db06NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/doctoralThesisapplication/pdfhttp://hdl.handle.net/10486/686546reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/6865462026-06-23T12:46:27Z
dc.title.none.fl_str_mv Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
title Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
spellingShingle Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
Ximendes, Erving Clayton
Nanotecnología - Tesis doctorales
Nanopartículas - Tesis doctorales
Física
title_short Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
title_full Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
title_fullStr Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
title_full_unstemmed Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
title_sort Multifunctional nanoparticles for hyperthermia, thermometry and fluorescenceimaging in the biological windows
dc.creator.none.fl_str_mv Ximendes, Erving Clayton
author Ximendes, Erving Clayton
author_facet Ximendes, Erving Clayton
author_role author
dc.contributor.none.fl_str_mv Jaque García, Daniel
Silva, Carlos Jacinto da
Departamento de Física de Materiales
Facultad de Ciencias
dc.subject.none.fl_str_mv Nanotecnología - Tesis doctorales
Nanopartículas - Tesis doctorales
Física
topic Nanotecnología - Tesis doctorales
Nanopartículas - Tesis doctorales
Física
description Tesis Doctoral inédita cotutelada por la Universidade Federal de Alagoas de Brasil y la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Física de Materiales. Fecha de lectura: 17-12-2018
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-12-17
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv http://hdl.handle.net/10486/686546
url http://hdl.handle.net/10486/686546
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301629

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