Short-term Tolerance to Inhaled Antibiotics in Patients With Bronchial Infection not Associated With Cystic Fibrosis

The use of intravenous antibiotic formulations delivered by inhalation is controversial. Tolerance can be an issue and some treatment guidelines discourage this route of administration if the same antibiotic is available in an inhalation formulation. This was a retrospective, observational, single-c...

Descripción completa

Detalles Bibliográficos
Autores: Máiz, Luis, Nieto, Rosa, Duran Barata, Diego, Máiz, José, Ruiz Calvo, Gabriel, Muriel, Alfonso, Barbero, Esther, Vélez Díaz-Pallarés, Manuel, Morillo, Raquel
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:dnet:abacusreposi::949fa62d56c0f4e9841e4506f169f51f
Acceso en línea:https://hdl.handle.net/11268/17080
Access Level:acceso abierto
Palabra clave:Medicina
Antibacterianos
Infecciones del Sistema Respiratorio
Tolerancia a Medicamentos
Medicamento
Aparato respiratorio
Investigación médica
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Descripción
Sumario:The use of intravenous antibiotic formulations delivered by inhalation is controversial. Tolerance can be an issue and some treatment guidelines discourage this route of administration if the same antibiotic is available in an inhalation formulation. This was a retrospective, observational, single-center study comparing tolerance to three antibiotics delivered by nebulization (intravenous formulations of ampicillin and gentamicin, and an inhalation formulation of colistimethate sodium) in patients with bronchial infection (BI), chronic bronchial infection (CBI), and/or recurrent respiratory infections. The study also aimed to identify factors potentially associated with tolerability.