Editorial: Multi-omics data integration: key to thoroughly understanding the immune system

The integration of platforms such as genomics, transcriptomics and proteomics has been acknowledged as a promising strategy for the in-depth characterization of complex cell systems and/or diseases. These omics platforms are now also helping us understand human immunity better. The immune system is...

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Detalles Bibliográficos
Autores: Jiménez, Cristina, Hernández-Sánchez, María, Dongen, J. J. M. van, Díez, Paula
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/337523
Acceso en línea:http://hdl.handle.net/10261/337523
Access Level:acceso abierto
Palabra clave:Multi-omics
Immune system
Cancer
Proteomics
Transcriptomics
Immune infiltration
Biomarker
Descripción
Sumario:The integration of platforms such as genomics, transcriptomics and proteomics has been acknowledged as a promising strategy for the in-depth characterization of complex cell systems and/or diseases. These omics platforms are now also helping us understand human immunity better. The immune system is a highly sophisticated network that maintains tissue homeostasis throughout the body. Thus, any disturbance in the immune system directly impacts diseases or indirectly drives malignant cell development. In this Research Topic, six manuscripts aim to describe the immune system by integrating different omics approaches, investigating the immunity functioning and its involvement in disease or the efficacy of therapeutical drug responses.