Additional file 1 of Feasibility of a genotyping system for the diagnosis of alpha1 antitrypsin deficiency: a multinational cross-sectional analysis

Figure 1S. Evolution over time of genetic study requests in Spain, LATAM and Turkey. Figure 2S. Evolution over time of requests for genetic studies by LATAM countries. Figure 3S. Distribution of sample types by geographical area. Figure 4S. Time elapsed between different steps by geographical area....

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Detalhes bibliográficos
Autores: López-Campos, J. L., Osaba, Lourdes, Czischke, Karen, Jardim, José R., Fernández Acquier, Mariano, Ali, Abraham, Günen, Hakan, Rapun, Noelia, Drobnic, Estrella, Miravitlles, Marc
Formato: conjunto de datos
Fecha de publicación:2022
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/331809
Acesso em linha:http://hdl.handle.net/10261/331809
Access Level:acceso abierto
Palavra-chave:Alpha1 antitrypsin deficiency
Diagnosis
Buccal swab
Dried blood spots
Genotyping
Descrição
Resumo:Figure 1S. Evolution over time of genetic study requests in Spain, LATAM and Turkey. Figure 2S. Evolution over time of requests for genetic studies by LATAM countries. Figure 3S. Distribution of sample types by geographical area. Figure 4S. Time elapsed between different steps by geographical area. Figure 5S. Allele distribution according to the different genotyping reasons in different Latin American countries. Table 1S. Description of the allelic variants and associated alleles tested by A1AT Genotyping Test; Information about the activity of the A1AT protein expressed. Table 2S. Cases in which sequencing revealed additional mutation from direct genotyping.