Epidemiology of resistant bacterial infections in patients with hematological malignancies or undergoing hematopoietic cell transplantation in Europe: A systematic review by the European Conference on Infections in Leukemia (ECIL)

[Background] Patients with hematological malignancies (HM) or undergoing hematopoietic cell transplantation (HCT) face high risk of bloodstream infections (BSI) during febrile neutropenia. Rising antimicrobial resistance (AMR), especially among Gram-negative (GN) bacteria, challenges effective empir...

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Detalles Bibliográficos
Autores: Baccelli, Francesco, Aguilar Guisado, Manuela, García-Vidal, Carolina, Mikulska, Malgorzata, Vanbiervliet, Yuri, Blijlevens, Nicole, Muñoz, Patricia, Neofytos, Dionysios, Cordonnier, Catherine, Calandra, Thierry, Averbuch, Dina, Akova, Murat
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/402456
Acceso en línea:http://hdl.handle.net/10261/402456
https://api.elsevier.com/content/abstract/scopus_id/105013634916
Access Level:acceso abierto
Palabra clave:Antimicrobial resistance
Bacterial infections
Colonization
Empirical antibiotic therapy
Epidemiology
Europe
Febrile neutropenia
Hematology
Hematopoietic cell transplantation
Leukemia
Descripción
Sumario:[Background] Patients with hematological malignancies (HM) or undergoing hematopoietic cell transplantation (HCT) face high risk of bloodstream infections (BSI) during febrile neutropenia. Rising antimicrobial resistance (AMR), especially among Gram-negative (GN) bacteria, challenges effective empirical antibiotic therapy (EAT) selection. This ECIL-10 systematic review updates European resistance epidemiology since the 2011 ECIL-4 guidelines publication to inform clinical recommendations.

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