Bringing immuno-assemblies to optoelectronics: sandwich assay integration of a nanostructured porous-silicon/gold-nanoparticle phototransistor

The exquisite specificity of biomolecular interactions can be used to integrate photonic and electronic components into nanomaterial-based architectures. In this line, a field-effect phototransistor based on Si/porous silicon (PSi) structures was fabricated by quantitatively attaching Gold nanoparti...

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Detalhes bibliográficos
Autores: Ramadan Shehata Ali, Rehab, Rodriguez, Chloé, Torres Costa, Vicente, Pini, Valerio, Martín Palma, Raúl José, Cebrián, Virginia, Calvo Membibre, Rodrigo, Ahumada, Óscar, Manso Silván, Miguel
Tipo de documento: artigo
Data de publicação:2021
País:España
Recursos:Universidad Autónoma de Madrid
Repositório:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglês
OAI Identifier:oai:repositorio.uam.es:10486/696441
Acesso em linha:http://hdl.handle.net/10486/696441
https://dx.doi.org/10.1016/j.mseb.2021.115271
Access Level:Acceso aberto
Palavra-chave:Immuno-assembly
Sandwich assay
Porous silicon
Gold nanoparticles
Phototransistor
Optoelectronics
Física
Descrição
Resumo:The exquisite specificity of biomolecular interactions can be used to integrate photonic and electronic components into nanomaterial-based architectures. In this line, a field-effect phototransistor based on Si/porous silicon (PSi) structures was fabricated by quantitatively attaching Gold nanoparticles (AuNPs) to the PSi surface by an immunoassay. Two antibodies, linked onto PSi and AuNPs, were used against different epitopes of prostate specific antigen, the common conjugating marker for these antibodies. Under white light illumination the photocurrent increases with increasing AuNP surface density. The gate voltage is effective in decoupling electron-hole pairs created at the nanostructured PSi interface. In turn, the main effect of the immune-assembled AuNPs is the optimization of charge transport through the surface. The analysis of the photocurrent shows an outstanding spectral selectivity in the 980 ± 50 nm NIR bandwidth. This report underlines the potential of the insertion of immune-assay protocols for the development of optoelectronic devices