Association between type 2 diabetes and chronic low back pain in general practices in Germany.

INTRODUCTION: There are conflicting results on the association between type 2 diabetes and chronic low back pain (CLBP). Therefore, the goal was to investigate the relationship between type 2 diabetes and CLBP in individuals followed in general practices in Germany. RESEARCH DESIGN AND METHODS: Adul...

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Detalles Bibliográficos
Autores: Jacob L, Rathmann W, Koyanagi A, Haro JM, Kostev K
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p19870
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19870
https://drc.bmj.com/content/9/1/e002426
Access Level:acceso abierto
Palabra clave:*cohort studies
*epidemiology
*low back pain
*type 2 diabetes
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spelling Association between type 2 diabetes and chronic low back pain in general practices in Germany.Jacob LRathmann WKoyanagi AHaro JMKostev K*cohort studies*epidemiology*low back pain*type 2 diabetesINTRODUCTION: There are conflicting results on the association between type 2 diabetes and chronic low back pain (CLBP). Therefore, the goal was to investigate the relationship between type 2 diabetes and CLBP in individuals followed in general practices in Germany. RESEARCH DESIGN AND METHODS: Adults diagnosed for the first time with type 2 diabetes in 809 general practices in Germany between 2005 and 2018 (index date) were included. Adults without type 2 diabetes were matched (1:1) to those with type 2 diabetes by sex, age, index year, and the annual number of medical consultations (index date: a randomly selected visit date). The association between type 2 diabetes and the 10-year incidence of CLBP was analyzed in conditional Cox regression models adjusted for a wide range of comorbidities, including hypertension, lipid metabolism disorders, and obesity. RESULTS: There were 139 002 individuals included in this study (women: 58.0%; mean (SD) age 62.5 (13.4) years). There was a positive association between type 2 diabetes and the incidence of CLBP in the overall sample (HR=1.23, 95% CI: 1.13 to 1.35). Sex-stratified analyses showed a higher risk of CLBP in women (HR=1.68, 95% CI: 1.43 to 1.90) and a lower risk in men with than in their counterparts without type 2 diabetes (HR=0.83, 95% CI: 0.71 to 0.97). CONCLUSIONS: Newly diagnosed type 2 diabetes was associated with an increased risk of CLBP. There were important sex differences in the type 2 diabetes-CLBP relationship, and more research is warranted to investigate the underlying factors explaining these differences.BMJ PUBLISHING GROUP2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19870https://drc.bmj.com/content/9/1/e002426BMJ Open Diabetes Research & CareISSN: 20524897reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p198702026-05-27T12:37:41Z
dc.title.none.fl_str_mv Association between type 2 diabetes and chronic low back pain in general practices in Germany.
title Association between type 2 diabetes and chronic low back pain in general practices in Germany.
spellingShingle Association between type 2 diabetes and chronic low back pain in general practices in Germany.
Jacob L
*cohort studies
*epidemiology
*low back pain
*type 2 diabetes
title_short Association between type 2 diabetes and chronic low back pain in general practices in Germany.
title_full Association between type 2 diabetes and chronic low back pain in general practices in Germany.
title_fullStr Association between type 2 diabetes and chronic low back pain in general practices in Germany.
title_full_unstemmed Association between type 2 diabetes and chronic low back pain in general practices in Germany.
title_sort Association between type 2 diabetes and chronic low back pain in general practices in Germany.
dc.creator.none.fl_str_mv Jacob L
Rathmann W
Koyanagi A
Haro JM
Kostev K
author Jacob L
author_facet Jacob L
Rathmann W
Koyanagi A
Haro JM
Kostev K
author_role author
author2 Rathmann W
Koyanagi A
Haro JM
Kostev K
author2_role author
author
author
author
dc.subject.none.fl_str_mv *cohort studies
*epidemiology
*low back pain
*type 2 diabetes
topic *cohort studies
*epidemiology
*low back pain
*type 2 diabetes
description INTRODUCTION: There are conflicting results on the association between type 2 diabetes and chronic low back pain (CLBP). Therefore, the goal was to investigate the relationship between type 2 diabetes and CLBP in individuals followed in general practices in Germany. RESEARCH DESIGN AND METHODS: Adults diagnosed for the first time with type 2 diabetes in 809 general practices in Germany between 2005 and 2018 (index date) were included. Adults without type 2 diabetes were matched (1:1) to those with type 2 diabetes by sex, age, index year, and the annual number of medical consultations (index date: a randomly selected visit date). The association between type 2 diabetes and the 10-year incidence of CLBP was analyzed in conditional Cox regression models adjusted for a wide range of comorbidities, including hypertension, lipid metabolism disorders, and obesity. RESULTS: There were 139 002 individuals included in this study (women: 58.0%; mean (SD) age 62.5 (13.4) years). There was a positive association between type 2 diabetes and the incidence of CLBP in the overall sample (HR=1.23, 95% CI: 1.13 to 1.35). Sex-stratified analyses showed a higher risk of CLBP in women (HR=1.68, 95% CI: 1.43 to 1.90) and a lower risk in men with than in their counterparts without type 2 diabetes (HR=0.83, 95% CI: 0.71 to 0.97). CONCLUSIONS: Newly diagnosed type 2 diabetes was associated with an increased risk of CLBP. There were important sex differences in the type 2 diabetes-CLBP relationship, and more research is warranted to investigate the underlying factors explaining these differences.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19870
https://drc.bmj.com/content/9/1/e002426
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19870
https://drc.bmj.com/content/9/1/e002426
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMJ PUBLISHING GROUP
publisher.none.fl_str_mv BMJ PUBLISHING GROUP
dc.source.none.fl_str_mv BMJ Open Diabetes Research & Care
ISSN: 20524897
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
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