De novo urethral hypermobility at 6 months after first delivery as a risk factor for SUI 12 years postpartum

Objective: to analyze the association between de novo urethral hypermobility 6 months postpartum and SUI symptoms at 6 months and 12 years after first delivery. Risk factors associated with the development of postnatal urethral hypermobility were also examined. Methods: A longitudinal cohort study w...

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Detalhes bibliográficos
Autores: Arrue Gabilondo, Miren, Belar, Maria, Díez Itza, Irene
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/76228
Acesso em linha:http://hdl.handle.net/10810/76228
Access Level:acceso abierto
Palavra-chave:hypermobility
urethral
stress urinary incontinence
delivery
parity
Descrição
Resumo:Objective: to analyze the association between de novo urethral hypermobility 6 months postpartum and SUI symptoms at 6 months and 12 years after first delivery. Risk factors associated with the development of postnatal urethral hypermobility were also examined. Methods: A longitudinal cohort study was conducted on primigravid women, after excluding those with UI before pregnancy and/or urethral hypermobility (rotational angle ≥ 30°) at term. At 6 months postpartum, SUI was assessed based on symptoms and introital ultrasound performed to measure rotational angle (difference between urethro-pelvic angle at rest and at maximum Valsalva). Twelve years after delivery, women were sent a questionnaire including SUI assessment and questions on parity, current age, and body mass index. Continuous variables were compared using Student’s t-test and qualitative variables using Chi-squared tests. A logistic regression model was constructed including variables that reached statistical significance (p< 0.05) in the univariate analysis. Results: Of the 314 women who completed the 6-month follow-up, 265 (84.4%) were successfully contacted and completed the questionnaire at 12 years and these formed the study group. In 127 women (47.9%), de novo urethral hypermobility had developed by 6 months postpartum. There was no association between urethral hypermobility and SUI symptoms 6 months postpartum (OR: 1.17; 95%CI 0.59-2.33). Twelve years after delivery, however, SUI was reported by 110 women overall (41.5%) and nearly half of the women who developed postnatal urethral hypermobility (61/127, 48.0%). Conclusion: De novo urethral hypermobility 6 months postpartum constitutes a risk factor for SUI 12 years later.