Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints

Several studies reported that healthy elderly with subjective memory complaints (SMC) evolve to Alzheimer’s disease (AD) more frequently than elderly without subjective memory decline. In the present study, we investigated event-related potentials (ERPs) associated to executive control processes tak...

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Detalles Bibliográficos
Autores: Cespón, Jesús, Galdo Álvarez, Santiago, Díaz Fernández, Fernando
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/22200
Acceso en línea:http://hdl.handle.net/10347/22200
Access Level:acceso abierto
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spelling Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory ComplaintsCespón, JesúsGaldo Álvarez, SantiagoDíaz Fernández, FernandoSeveral studies reported that healthy elderly with subjective memory complaints (SMC) evolve to Alzheimer’s disease (AD) more frequently than elderly without subjective memory decline. In the present study, we investigated event-related potentials (ERPs) associated to executive control processes taking place during the performance of a Simon task with two irrelevant dimensions (stimulus position and direction pointed by an arrow) in healthy elderly divided in low and high SMC (LSMC, HSMC) groups. P300 was studied as a correlate of working memory. Medial frontal negativity (MFN) was studied as a correlate of conflict monitoring. Whereas the LSMC group showed interference from the stimulus position, participants with HSMC showed interference from both irrelevant dimensions. P300 latency was longer and P300 amplitude was lower when the stimulus position was incompatible with the required response but differences between both groups were not observed. MFN was not modulated in the LSMC group; however, the HSMC group showed larger MFN when the stimulus position and/or the direction pointed by the arrow were incompatible with the required response. These results suggest that participants with HSMC deployed greater conflict monitoring activity to maintain the performance when the target stimulus contained conflictive spatial information.Frontiers MediaUniversidade de Santiago de Compostela. Departamento de Psicoloxía Clínica e Psicobioloxía20182018-01-0120182018-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10347/22200reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)InglésengMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 PSI2014-55316-C3-3-R EVOLUCION DEL DETERIORO COGNITIVO EN EL ENVEJECIMIENTO NORMAL, DCL Y EA: ESTUDIO LONGITUDINAL CON MARCADORES PSICOFISIOLOGICOS Y DE NEUROIMAGEN FUNCIONALAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PSI2017-89389-C2-2-R ESTUDIO LONGITUDINAL DEL DETERIORO COGNITIVO EN EL DCL Y EA CON MARCADORES NEUROCOGNITIVOS. EFECTOS DE LA EST ELECTRICA T. EN UN PROGRAMA INTEGRADO DE EST. COGNITIVAopen accesshttp://purl.org/coar/access_right/c_abf2© 2018 Cespón, Galdo-Álvarez and Díaz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these termshttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/222002026-06-15T12:47:27Z
dc.title.none.fl_str_mv Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
title Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
spellingShingle Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
Cespón, Jesús
title_short Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
title_full Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
title_fullStr Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
title_full_unstemmed Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
title_sort Event-Related Potentials Reveal Altered Executive Control Activity in Healthy Elderly With Subjective Memory Complaints
dc.creator.none.fl_str_mv Cespón, Jesús
Galdo Álvarez, Santiago
Díaz Fernández, Fernando
author Cespón, Jesús
author_facet Cespón, Jesús
Galdo Álvarez, Santiago
Díaz Fernández, Fernando
author_role author
author2 Galdo Álvarez, Santiago
Díaz Fernández, Fernando
author2_role author
author
dc.contributor.none.fl_str_mv Universidade de Santiago de Compostela. Departamento de Psicoloxía Clínica e Psicobioloxía
description Several studies reported that healthy elderly with subjective memory complaints (SMC) evolve to Alzheimer’s disease (AD) more frequently than elderly without subjective memory decline. In the present study, we investigated event-related potentials (ERPs) associated to executive control processes taking place during the performance of a Simon task with two irrelevant dimensions (stimulus position and direction pointed by an arrow) in healthy elderly divided in low and high SMC (LSMC, HSMC) groups. P300 was studied as a correlate of working memory. Medial frontal negativity (MFN) was studied as a correlate of conflict monitoring. Whereas the LSMC group showed interference from the stimulus position, participants with HSMC showed interference from both irrelevant dimensions. P300 latency was longer and P300 amplitude was lower when the stimulus position was incompatible with the required response but differences between both groups were not observed. MFN was not modulated in the LSMC group; however, the HSMC group showed larger MFN when the stimulus position and/or the direction pointed by the arrow were incompatible with the required response. These results suggest that participants with HSMC deployed greater conflict monitoring activity to maintain the performance when the target stimulus contained conflictive spatial information.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01
2018
2018-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10347/22200
url http://hdl.handle.net/10347/22200
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 PSI2014-55316-C3-3-R EVOLUCION DEL DETERIORO COGNITIVO EN EL ENVEJECIMIENTO NORMAL, DCL Y EA: ESTUDIO LONGITUDINAL CON MARCADORES PSICOFISIOLOGICOS Y DE NEUROIMAGEN FUNCIONAL
Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PSI2017-89389-C2-2-R ESTUDIO LONGITUDINAL DEL DETERIORO COGNITIVO EN EL DCL Y EA CON MARCADORES NEUROCOGNITIVOS. EFECTOS DE LA EST ELECTRICA T. EN UN PROGRAMA INTEGRADO DE EST. COGNITIVA
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
repository.mail.fl_str_mv
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