Computer-aided Glaucoma Diagnosis using Stochastic Watershed Transformation on Single Fundus Images

[EN] Glaucoma is a chronic eye disease and one of the major causes of permanent blindness. Since it does not show initial symptoms, early diagnosis is important to limit its progression. This paper presents an automatic optic nerve characterization algorithm for glaucoma diagnosis based only on reti...

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Detalhes bibliográficos
Autores: Díaz-Pinto, Andrés Yesid, Navea, Amparo, Morales, Sandra|||0000-0003-0763-1545, Naranjo Ornedo, Valeriana|||0000-0002-0181-3412
Tipo de documento: artigo
Data de publicação:2019
País:España
Recursos:Universitat Politècnica de València (UPV)
Repositório:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglês
OAI Identifier:oai:riunet.upv.es:10251/126176
Acesso em linha:https://riunet.upv.es/handle/10251/126176
Access Level:Acceso aberto
Palavra-chave:Glaucoma
Fundus Images
Stochastic Watershed
CDR
ISNT rule
TEORIA DE LA SEÑAL Y COMUNICACIONES
Descrição
Resumo:[EN] Glaucoma is a chronic eye disease and one of the major causes of permanent blindness. Since it does not show initial symptoms, early diagnosis is important to limit its progression. This paper presents an automatic optic nerve characterization algorithm for glaucoma diagnosis based only on retinal fundus images. For optic cup segmentation, we used a new method based on the stochastic watershed transformation applied on the YIQ colour space to extract clinical indicators such as the Cup/Disc ratio, the area Cup/Disc ratio and the ISNT rule. Afterwards, an assessment between normal and glaucomatous fundus images is performed. The proposed algorithm was evaluated on 6 different (private and public) databases containing 723 images (377 normal and 346 glaucomatous images) which achieved a specificity and sensitivity of 0.674 and 0.675, respectively. Moreover, an F-score of 0.770 was obtained when evaluating this method on the publicly available database Drishti-GS1. A comparison of the proposed work with other state-of-the-art methods demonstrates the robustness of the proposed algorithm; because it was tested using images from different databases with high variability, which is a common issue in this area. Additional comparisons with existing works for cup segmentation, that use the publicly available database Drishti-GS1, are also presented in this paper.