Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study

Malnutrition is highly prevalent in older persons with dementia. Therefore, strong predictors of malnutrition in this population are crucial to initiating early interventions. This study evaluates the association between the probability of having malnutrition with the muscle volume and intramuscular...

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Autores: Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d, Bani-Hassan, E. (Ebrahim)|||/items/bba00869-4ace-4701-bda6-66c6136f89e7, Weon, J.H. (Jang Ho)|||/items/76d63639-5730-44d7-a6ba-f2b82f17ddbf, Wakabayashi, H. (Hidetaka)|||/items/0824cbce-ca78-4735-a4ce-201adf9bf8fe, Tovar-Ríos, D.A. (Diego Alejandro)|||/items/1aaf0d54-35e3-4a37-9a7e-b3084b7538ba, Oppedal, K. (Ketil)|||/items/7dd0d1dd-1975-4304-9a19-a2e241bc98ee, Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1, Duque, G. (Gustavo)|||/items/be10365b-0620-4d45-8661-abf8414e2ec0
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/121748
Acceso en línea:https://hdl.handle.net/10171/121748
Access Level:acceso abierto
Palabra clave:Dementia
Intramuscular fat
Lewy body dementia
Malnutrition
Sarcopenia
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repository_id_str
spelling Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up StudyBorda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228dBani-Hassan, E. (Ebrahim)|||/items/bba00869-4ace-4701-bda6-66c6136f89e7Weon, J.H. (Jang Ho)|||/items/76d63639-5730-44d7-a6ba-f2b82f17ddbfWakabayashi, H. (Hidetaka)|||/items/0824cbce-ca78-4735-a4ce-201adf9bf8feTovar-Ríos, D.A. (Diego Alejandro)|||/items/1aaf0d54-35e3-4a37-9a7e-b3084b7538baOppedal, K. (Ketil)|||/items/7dd0d1dd-1975-4304-9a19-a2e241bc98eeAarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1Duque, G. (Gustavo)|||/items/be10365b-0620-4d45-8661-abf8414e2ec0DementiaIntramuscular fatLewy body dementiaMalnutritionSarcopeniaMalnutrition is highly prevalent in older persons with dementia. Therefore, strong predictors of malnutrition in this population are crucial to initiating early interventions. This study evaluates the association between the probability of having malnutrition with the muscle volume and intramuscular fat (iMAT) of the masseter and the tongue in magnetic resonance imaging (MRI) of community-dwelling older persons diagnosed with mild dementia followed up for 5 years. This is a longitudinal study conducted in the western part of Norway. Muscle volume and iMAT of the tongue and masseter were computed from structural head MRI obtained from 65 participants of the Dementia Study of Western Norway using Slice-O-Matic software for segmentation. Malnutrition was assessed using the Global Leadership Initiative on Malnutrition Index. Linear mixed models were conducted. Having malnutrition at baseline was associated with lower muscle volume (odds ratio [OR] 0.60, standard error [SE] 0.20; p = .010) and higher iMAT (OR 3.31, SE 0.46; p = .010) in the tongue. At 5 years follow-up, those with lower muscle volume (OR 0.55, SE 0.20; p = .002) and higher iMAT (OR 2.52, SE 0.40; p = .022) in the tongue had a higher probability of presenting malnutrition. The masseter iMAT and volume were not associated with malnutrition in any of the adjusted models. In people diagnosed with mild dementia, tongue muscle volume and iMAT were associated with baseline malnutrition and the probability of developing malnutrition in a 5-year trajectory. In the masseter, there were no significant associations after adjustments.Oxford AcademicDadun. Depósito Académico Digital Universidad de Navarra20222022-01-0120222022-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/121748reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/1217482026-06-21T12:47:57Z
dc.title.none.fl_str_mv Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
title Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
spellingShingle Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d
Dementia
Intramuscular fat
Lewy body dementia
Malnutrition
Sarcopenia
title_short Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
title_full Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
title_fullStr Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
title_full_unstemmed Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
title_sort Muscle Volume and Intramuscular Fat of the Tongue Evaluated With MRI Predict Malnutrition in People Living With Dementia: A 5-Year Follow-up Study
dc.creator.none.fl_str_mv Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d
Bani-Hassan, E. (Ebrahim)|||/items/bba00869-4ace-4701-bda6-66c6136f89e7
Weon, J.H. (Jang Ho)|||/items/76d63639-5730-44d7-a6ba-f2b82f17ddbf
Wakabayashi, H. (Hidetaka)|||/items/0824cbce-ca78-4735-a4ce-201adf9bf8fe
Tovar-Ríos, D.A. (Diego Alejandro)|||/items/1aaf0d54-35e3-4a37-9a7e-b3084b7538ba
Oppedal, K. (Ketil)|||/items/7dd0d1dd-1975-4304-9a19-a2e241bc98ee
Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1
Duque, G. (Gustavo)|||/items/be10365b-0620-4d45-8661-abf8414e2ec0
author Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d
author_facet Borda-Borda, M.G. (Miguel German)|||/items/681ecdf1-0f23-4003-a702-417198fd228d
Bani-Hassan, E. (Ebrahim)|||/items/bba00869-4ace-4701-bda6-66c6136f89e7
Weon, J.H. (Jang Ho)|||/items/76d63639-5730-44d7-a6ba-f2b82f17ddbf
Wakabayashi, H. (Hidetaka)|||/items/0824cbce-ca78-4735-a4ce-201adf9bf8fe
Tovar-Ríos, D.A. (Diego Alejandro)|||/items/1aaf0d54-35e3-4a37-9a7e-b3084b7538ba
Oppedal, K. (Ketil)|||/items/7dd0d1dd-1975-4304-9a19-a2e241bc98ee
Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1
Duque, G. (Gustavo)|||/items/be10365b-0620-4d45-8661-abf8414e2ec0
author_role author
author2 Bani-Hassan, E. (Ebrahim)|||/items/bba00869-4ace-4701-bda6-66c6136f89e7
Weon, J.H. (Jang Ho)|||/items/76d63639-5730-44d7-a6ba-f2b82f17ddbf
Wakabayashi, H. (Hidetaka)|||/items/0824cbce-ca78-4735-a4ce-201adf9bf8fe
Tovar-Ríos, D.A. (Diego Alejandro)|||/items/1aaf0d54-35e3-4a37-9a7e-b3084b7538ba
Oppedal, K. (Ketil)|||/items/7dd0d1dd-1975-4304-9a19-a2e241bc98ee
Aarsland, D. (Dag)|||/items/7f4024e7-2d11-43cf-8b41-29752ddf75e1
Duque, G. (Gustavo)|||/items/be10365b-0620-4d45-8661-abf8414e2ec0
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Dementia
Intramuscular fat
Lewy body dementia
Malnutrition
Sarcopenia
topic Dementia
Intramuscular fat
Lewy body dementia
Malnutrition
Sarcopenia
description Malnutrition is highly prevalent in older persons with dementia. Therefore, strong predictors of malnutrition in this population are crucial to initiating early interventions. This study evaluates the association between the probability of having malnutrition with the muscle volume and intramuscular fat (iMAT) of the masseter and the tongue in magnetic resonance imaging (MRI) of community-dwelling older persons diagnosed with mild dementia followed up for 5 years. This is a longitudinal study conducted in the western part of Norway. Muscle volume and iMAT of the tongue and masseter were computed from structural head MRI obtained from 65 participants of the Dementia Study of Western Norway using Slice-O-Matic software for segmentation. Malnutrition was assessed using the Global Leadership Initiative on Malnutrition Index. Linear mixed models were conducted. Having malnutrition at baseline was associated with lower muscle volume (odds ratio [OR] 0.60, standard error [SE] 0.20; p = .010) and higher iMAT (OR 3.31, SE 0.46; p = .010) in the tongue. At 5 years follow-up, those with lower muscle volume (OR 0.55, SE 0.20; p = .002) and higher iMAT (OR 2.52, SE 0.40; p = .022) in the tongue had a higher probability of presenting malnutrition. The masseter iMAT and volume were not associated with malnutrition in any of the adjusted models. In people diagnosed with mild dementia, tongue muscle volume and iMAT were associated with baseline malnutrition and the probability of developing malnutrition in a 5-year trajectory. In the masseter, there were no significant associations after adjustments.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-01
2022
2022-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/121748
url https://hdl.handle.net/10171/121748
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford Academic
publisher.none.fl_str_mv Oxford Academic
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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