Image similarity for registration and manifold learning: application to brain analysis

The aim of this thesis is to explore and develop measures for image comparison in two main areas of medical image analysis: image registration and manifold learning for population analysis. In particular, the main contributions of the thesis are the following: (i) the development of a multimodal sim...

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Detalles Bibliográficos
Autor: Zimmer, Veronika Anne
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:CBUC, CESCA
Repositorio:TDR. Tesis Doctorales en Red
OAI Identifier:oai:www.tdx.cat:10803/402101
Acceso en línea:http://hdl.handle.net/10803/402101
Access Level:acceso abierto
Palabra clave:Similarity measure
Image registration
Simultaneous diagonalization
Laplacian commutator
Manifold learning
Manifold embedding quality
Kernel combinations
Random forest
Neighborhood approximation
Brain analysis
Medido de similitud
Registro de imagen
Diagonalización simultáneo
Comutador de Laplaciano
Cualidad de embeddings
Combinación de kernels
Aproximación de vecindarios
Análisis del cerebro
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Descripción
Sumario:The aim of this thesis is to explore and develop measures for image comparison in two main areas of medical image analysis: image registration and manifold learning for population analysis. In particular, the main contributions of the thesis are the following: (i) the development of a multimodal similarity measure using the commutativity of the image graph Laplacians as a criterion of image structure preservation, (ii) the application of such similarity measure to fetal ultrasound-magnetic resonance registration, (iii) the development of a framework for optimal kernel-based manifold embeddings for medical image data, and (iv) the development of a method to learn and combine heterogeneous pairwise image similarities induced by application-specific distance functions for manifold learning. The methods developed in this thesis were evaluated both on synthetic and clinical data, here in particular for brain analysis and classification, both during early childhood and in aging adults.