Clinical leishmaniosis in a domestic ferret (Mustela putorius furo) treated with miltefosine plus allopurinol: Serological and clinical follow-up

The published information on the treatment of mustelid leishmaniosis is extremely scarce because there are only two case reports available. In one case, a domestic ferret (Mustela putorius furo) was treated with a combination of meglumine antimoniate plus allopurinol and, in the other case, a therap...

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Detalles Bibliográficos
Autores: Giner, Jacobo, Villanueva-Saz, Sergio, Alcover Amengual, Maria Magdalena, Riera Lizandra, Ma. Cristina, Fisa Saladrigas, Roser, Verde, María Teresa, Fernández, Antonio, Yzuel, Andrés
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2021
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/179101
Acceso en línea:https://hdl.handle.net/2445/179101
Access Level:acceso abierto
Palabra clave:Leishmaniosi
Malalties infeccioses en els animals
Parasitologia veterinària
Leishmaniasis
Communicable diseases in animals
Veterinary parasitology
Descripción
Sumario:The published information on the treatment of mustelid leishmaniosis is extremely scarce because there are only two case reports available. In one case, a domestic ferret (Mustela putorius furo) was treated with a combination of meglumine antimoniate plus allopurinol and, in the other case, a therapeutic regimen with allopurinol was administrated to a Eurasian otter (Lutra lutra). This article describes for the first time a combined therapeutic protocol with miltefosine (2 mg/kg once a day during 28 days per os), and allopurinol (10 mg/kg twice a day PO sine die) in a domestic ferret with splenomegaly, lymphadenomegaly and a facial pyogranulomatous dermatitis, with a moderate level of antibodies to Leishmania infantum.