Minimal information for studies of extracellular vesicles 2018 (MISEV2018)

The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles,...

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Detalles Bibliográficos
Autores: Théry, Clotilde|||0000-0001-8294-6884, Witwer, Kenneth W.|||0000-0003-1664-4233, Aikawa, Elena, Alcaraz, Maria Jose, Anderson, Johnathon D., Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K., Ayre, D. Craig, Bach, Jean-Marie, Bachurski, Daniel, Baharvand, Hossein, Balaj, Leonora, Baldacchino, Shawn, Bauer, Natalie N., Baxter, Amy A., Bebawy, Mary, Beckham, Carla, Bedina Zavec, Apolonija, Benmoussa, Abderrahim, Berardi, Anna C., Bergese, Paolo, Bielska, Ewa, Blenkiron, Cherie, Bobis-Wozowicz, Sylwia, Boilard, Eric, Boireau, Wilfrid, Bongiovanni, Antonella, Borràs i Serres, Francesc Enric|||0000-0003-4038-1912, Bosch, Steffi, Boulanger, Chantal M., Breakefield, Xandra, Breglio, Andrew M., Brennan, Meadhbh Á., Brigstock, David R., Brisson, Alain, Broekman, Marike L. D., Bromberg, Jacqueline F., Bryl-Górecka, Paulina, Buch, Shilpa, Buck, Amy H., Burger, Dylan, Busatto, Sara, Buschmann, Dominik, Bussolati, Benedetta, Buzás, Edit I., Byrd, James Bryan, Camussi, Giovanni, Carter, David R. F., Caruso, Sarah, Chamley, Lawrence W., Chang, Yu-Ting, Chen, Chihchen, Chen, Shuai, Cheng, Lesley, Chin, Andrew R., Clayton, Aled, Clerici, Stefano P., Cocks, Alex, Cocucci, Emanuele, Coffey, Robert J., Cordeiro-da-Silva, A.|||0000-0003-2392-6087, Couch, Yvonne, Coumans, Frank A. W., Coyle, Beth, Crescitelli, Rossella, Criado, Miria Ferreira, D'Souza-Schorey, Crislyn, Das, Saumya, Datta Chaudhuri, Amrita, de Candia, Paola, De Santana, Eliezer F., De Wever, Olivier, Del Portillo, Hernando A.|||0000-0002-5278-3452, Demaret, Tanguy, Deville, Sarah, Devitt, Andrew, Dhondt, Bert, Di Vizio, Dolores, Dieterich, Lothar C., Dolo, Vincenza, Dominguez Rubio, Ana Paula, Dominici, Massimo, Dourado, Mauricio R., Driedonks, Tom A. P., Duarte, Filipe V., Duncan, Heather M., Eichenberger, Ramon M., Ekström, Karin, E. L. Andaloussi, Samir, Elie-Caille, Celine, Erdbrügger, Uta, Falcón-Pérez, Juan M.|||0000-0003-3133-0670, Fatima, Farah, Fish, Jason E., Flores-Bellver, Miguel, Försönits, András, Frelet-Barrand, Annie, Fricke, Fabia, Fuhrmann, Gregor, Gabrielsson, Susanne, Gámez-Valero, Ana|||0000-0002-9530-2751, Gardiner, Chris, Gärtner, Kathrin, Gaudin, Raphael, Gho, Yong Song, Giebel, Bernd, Gilbert, Caroline, Gimona, Mario, Giusti, Ilaria, Goberdhan, Deborah C. I., Görgens, André, Gorski, Sharon M., Greening, David W., Gross, Julia Christina, Gualerzi, Alice, Gupta, Gopal N., Gustafson, Dakota, Handberg, Aase, Haraszti, Reka A., Harrison, Paul, Hegyesi, Hargita, Hendrix, An, Hill, Andrew F., Hochberg, Fred H., Hoffmann, Karl F., Holder, Beth, Holthofer, Harry, Hosseinkhani, Baharak, Hu, Guoku, Huang, Yiyao, Huber, Veronica, Hunt, Stuart, Ibrahim, Ahmed Gamal-Eldin, Ikezu, Tsuneya, Inal, Jameel M., Isin, Mustafa, Ivanova, Alena, Jackson, Hannah K., Jacobsen, Søren, Jay, Steven M., Jayachandran, Muthuvel, Jenster, Guido|||0000-0002-8658-2552, Jiang, Lanzhou, Johnson, Suzanne M., Jones, Jennifer C., Jong, Ambrose, Jovanovic-Talisman, Tijana, Jung, Stephanie, Kalluri, Raghu, Kano, Shin-ichi, Kaur, Sukhbir, Kawamura, Yumi, Keller, Evan T., Khamari, Delaram, Khomyakova, Elena, Khvorova, Anastasia, Kierulf, Peter, Kim, Kwang Pyo, Kislinger, Thomas, Klingeborn, Mikael, Klinke, David J., Kornek, Miroslaw, Kosanović, Maja M., Kovács, Árpád Ferenc, Krämer-Albers, Eva-Maria, Krasemann, Susanne, Krause, Mirja, Kurochkin, Igor V., Kusuma, Gina D., Kuypers, Sören, Laitinen, Saara, Langevin, Scott M., Languino, Lucia R., Lannigan, Joanne, Lässer, Cecilia, Laurent, Louise C., Lavieu, Gregory, Lázaro-Ibáñez, Elisa, Le Lay, Soazig, Lee, Myung-Shin, Lee, Yi Xin Fiona, Lemos, Debora S., Lenassi, Metka, Leszczynska, Aleksandra, Li, Isaac T. S., Liao, Ke, Libregts, Sten F., Ligeti, Erzsebet, Lim, Rebecca, Lim, Sai Kiang, Linē, Aija, Linnemannstöns, Karen, Llorente, Alicia, Lombard, Catherine A., Lorenowicz, Magdalena J., Lörincz, Ákos M., Lötvall, Jan, Lovett, Jason, Lowry, Michelle C., Loyer, Xavier, Lu, Quan, Lukomska, Barbara, Lunavat, Taral R., Maas, Sybren L. N., Malhi, Harmeet, Marcilla, Antonio|||0000-0003-0004-0531, Mariani, Jacopo, Mariscal, Javier, Martens-Uzunova, Elena S., Martin-Jaular, Lorena, Martinez, M. Carmen, Martins, Vilma Regina, Mathieu, Mathilde, Mathivanan, Suresh, Maugeri, Marco, McGinnis, Lynda K., McVey, Mark J., Meckes, David G., Meehan, Katie L., Mertens, Inge, Minciacchi, Valentina R., Möller, Andreas, Møller Jørgensen, Malene, Morales-Kastresana, Aizea, Morhayim, Jess, Mullier, François, Muraca, Maurizio, Musante, Luca, Mussack, Veronika, Muth, Dillon C., Myburgh, Kathryn H., Najrana, Tanbir, Nawaz, Muhammad, Nazarenko, Irina, Nejsum, Peter, Neri, Christian, Neri, Tommaso, Nieuwland, Rienk, Nimrichter, Leonardo, Nolan, John P., Nolte-'t Hoen, Esther N. M., Noren Hooten, Nicole, O'Driscoll, Lorraine, O'Grady, Tina, O'Loghlen, Ana, Ochiya, Takahiro, Olivier, Martin, Ortiz, Alberto|||0000-0002-9805-9523, Ortiz, Luis A., Osteikoetxea, Xabier, Østergaard, Ole, Ostrowski, Matias, Park, Jaesung, Pegtel, D. Michiel, Peinado, Héctor|||0000-0002-4256-3413, Perut, Francesca, Pfaffl, Michael W., Phinney, Donald G., Pieters, Bartijn C. H., Pink, Ryan C., Pisetsky, David S., Pogge von Strandmann, Elke, Polakovicova, Iva, Poon, Ivan K. H., Powell, Bonita H., Prada, Ilaria, Pulliam, Lynn, Quesenberry, Peter, Radeghieri, Annalisa, Raffai, Robert L., Raimondo, Stefania, Rak, Janusz, Ramirez, Marcel I., Raposo, Graça, Rayyan, Morsi S., Regev-Rudzki, Neta, Ricklefs, Franz L., Robbins, Paul D., Roberts, David D., Rodrigues, Silvia C., Rohde, Eva, Rome, Sophie, Rouschop, Kasper M. A., Rughetti, Aurelia, Russell, Ashley E., Saá, Paula, Sahoo, Susmita, Salas-Huenuleo, Edison, Sánchez, Catherine, Saugstad, Julie A., Saul, Meike J., Schiffelers, Raymond M., Schneider, Raphael, Schøyen, Tine Hiorth, Scott, Aaron, Shahaj, Eriomina, Sharma, Shivani, Shatnyeva, Olga, Shekari, Faezeh, Shelke, Ganesh Vilas, Shetty, Ashok K., Shiba, Kiyotaka, Siljander, Pia R-M., Silva, Andreia M., Skowronek, Agata, Snyder, Orman L., Soares, Rodrigo Pedro, Sódar, Barbara W., Soekmadji, Carolina, Sotillo, Javier, Stahl, Philip D., Stoorvogel, Willem, Stott, Shannon L., Strasser, Erwin F., Swift, Simon, Tahara, Hidetoshi, Tewari, Muneesh, Timms, Kate, Tiwari, Swasti, Tixeira, Rochelle, Tkach, Mercedes, Toh, Wei Seong, Tomasini, Richard, Torrecilhas, Ana Claudia, Tosar, Juan Pablo, Toxavidis, Vasilis, Urbanelli, Lorena, Vader, Pieter, van Balkom, Bas W. M., van der Grein, Susanne G., Van Deun, Jan, van Herwijnen, Martijn J. C., Van Keuren-Jensen, Kendall, van Niel, Guillaume, Van Royen, Martin E., van Wijnen, Andre J., Vasconcelos, M. Helena, Vechetti, Ivan J., Veit, Tiago D., Vella, Laura J., Velot, Émilie, Verweij, Frederik J., Vestad, Beate, Viñas, Jose L., Visnovitz, Tamás, Vukman, Krisztina V., Wahlgren, Jessica, Watson, Dionysios C., Wauben, Marca H. M., Weaver, Alissa, Webber, Jason P., Weber, Viktoria, Wehman, Ann M., Weiss, Daniel J., Welsh, Joshua A., Wendt, Sebastian, Wheelock, Asa M., Wiener, Zoltán, Witte, Leonie, Wolfram, Joy, Xagorari, Angeliki, Xander, Patricia, Xu, Jing, Yan, Xiaomei, Yáñez-Mó, María|||0000-0001-7484-2866, Yin, Hang, Yuana, Yuana, Zappulli, Valentina, Zarubova, Jana, Žėkas, Vytautas, Zhang, Jian-ye, Zhao, Zezhou, Zheng, Lei, Zheutlin, Alexander R., Zickler, Antje M., Zimmermann, Pascale, Zivkovic, Angela M., Zocco, Davide, Zuba-Surma, Ewa K.
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:253238
Acceso en línea:https://ddd.uab.cat/record/253238
https://dx.doi.org/urn:doi:10.1080/20013078.2018.1535750
Access Level:acceso abierto
Palabra clave:Extracellular vesicles
Exosomes
Ectosomes
Microvesicles
Minimal information requirements
Guidelines
Standardization
Microparticles
Rigor
Reproducibility
id ES_6b5f640da0b50e07fe018df0db99f449
oai_identifier_str oai:ddd.uab.cat:253238
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
title Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
spellingShingle Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
Théry, Clotilde|||0000-0001-8294-6884
Extracellular vesicles
Exosomes
Ectosomes
Microvesicles
Minimal information requirements
Guidelines
Standardization
Microparticles
Rigor
Reproducibility
title_short Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
title_full Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
title_fullStr Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
title_full_unstemmed Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
title_sort Minimal information for studies of extracellular vesicles 2018 (MISEV2018)
dc.creator.none.fl_str_mv Théry, Clotilde|||0000-0001-8294-6884
Witwer, Kenneth W.|||0000-0003-1664-4233
Aikawa, Elena
Alcaraz, Maria Jose
Anderson, Johnathon D.
Andriantsitohaina, Ramaroson
Antoniou, Anna
Arab, Tanina
Archer, Fabienne
Atkin-Smith, Georgia K.
Ayre, D. Craig
Bach, Jean-Marie
Bachurski, Daniel
Baharvand, Hossein
Balaj, Leonora
Baldacchino, Shawn
Bauer, Natalie N.
Baxter, Amy A.
Bebawy, Mary
Beckham, Carla
Bedina Zavec, Apolonija
Benmoussa, Abderrahim
Berardi, Anna C.
Bergese, Paolo
Bielska, Ewa
Blenkiron, Cherie
Bobis-Wozowicz, Sylwia
Boilard, Eric
Boireau, Wilfrid
Bongiovanni, Antonella
Borràs i Serres, Francesc Enric|||0000-0003-4038-1912
Bosch, Steffi
Boulanger, Chantal M.
Breakefield, Xandra
Breglio, Andrew M.
Brennan, Meadhbh Á.
Brigstock, David R.
Brisson, Alain
Broekman, Marike L. D.
Bromberg, Jacqueline F.
Bryl-Górecka, Paulina
Buch, Shilpa
Buck, Amy H.
Burger, Dylan
Busatto, Sara
Buschmann, Dominik
Bussolati, Benedetta
Buzás, Edit I.
Byrd, James Bryan
Camussi, Giovanni
Carter, David R. F.
Caruso, Sarah
Chamley, Lawrence W.
Chang, Yu-Ting
Chen, Chihchen
Chen, Shuai
Cheng, Lesley
Chin, Andrew R.
Clayton, Aled
Clerici, Stefano P.
Cocks, Alex
Cocucci, Emanuele
Coffey, Robert J.
Cordeiro-da-Silva, A.|||0000-0003-2392-6087
Couch, Yvonne
Coumans, Frank A. W.
Coyle, Beth
Crescitelli, Rossella
Criado, Miria Ferreira
D'Souza-Schorey, Crislyn
Das, Saumya
Datta Chaudhuri, Amrita
de Candia, Paola
De Santana, Eliezer F.
De Wever, Olivier
Del Portillo, Hernando A.|||0000-0002-5278-3452
Demaret, Tanguy
Deville, Sarah
Devitt, Andrew
Dhondt, Bert
Di Vizio, Dolores
Dieterich, Lothar C.
Dolo, Vincenza
Dominguez Rubio, Ana Paula
Dominici, Massimo
Dourado, Mauricio R.
Driedonks, Tom A. P.
Duarte, Filipe V.
Duncan, Heather M.
Eichenberger, Ramon M.
Ekström, Karin
E. L. Andaloussi, Samir
Elie-Caille, Celine
Erdbrügger, Uta
Falcón-Pérez, Juan M.|||0000-0003-3133-0670
Fatima, Farah
Fish, Jason E.
Flores-Bellver, Miguel
Försönits, András
Frelet-Barrand, Annie
Fricke, Fabia
Fuhrmann, Gregor
Gabrielsson, Susanne
Gámez-Valero, Ana|||0000-0002-9530-2751
Gardiner, Chris
Gärtner, Kathrin
Gaudin, Raphael
Gho, Yong Song
Giebel, Bernd
Gilbert, Caroline
Gimona, Mario
Giusti, Ilaria
Goberdhan, Deborah C. I.
Görgens, André
Gorski, Sharon M.
Greening, David W.
Gross, Julia Christina
Gualerzi, Alice
Gupta, Gopal N.
Gustafson, Dakota
Handberg, Aase
Haraszti, Reka A.
Harrison, Paul
Hegyesi, Hargita
Hendrix, An
Hill, Andrew F.
Hochberg, Fred H.
Hoffmann, Karl F.
Holder, Beth
Holthofer, Harry
Hosseinkhani, Baharak
Hu, Guoku
Huang, Yiyao
Huber, Veronica
Hunt, Stuart
Ibrahim, Ahmed Gamal-Eldin
Ikezu, Tsuneya
Inal, Jameel M.
Isin, Mustafa
Ivanova, Alena
Jackson, Hannah K.
Jacobsen, Søren
Jay, Steven M.
Jayachandran, Muthuvel
Jenster, Guido|||0000-0002-8658-2552
Jiang, Lanzhou
Johnson, Suzanne M.
Jones, Jennifer C.
Jong, Ambrose
Jovanovic-Talisman, Tijana
Jung, Stephanie
Kalluri, Raghu
Kano, Shin-ichi
Kaur, Sukhbir
Kawamura, Yumi
Keller, Evan T.
Khamari, Delaram
Khomyakova, Elena
Khvorova, Anastasia
Kierulf, Peter
Kim, Kwang Pyo
Kislinger, Thomas
Klingeborn, Mikael
Klinke, David J.
Kornek, Miroslaw
Kosanović, Maja M.
Kovács, Árpád Ferenc
Krämer-Albers, Eva-Maria
Krasemann, Susanne
Krause, Mirja
Kurochkin, Igor V.
Kusuma, Gina D.
Kuypers, Sören
Laitinen, Saara
Langevin, Scott M.
Languino, Lucia R.
Lannigan, Joanne
Lässer, Cecilia
Laurent, Louise C.
Lavieu, Gregory
Lázaro-Ibáñez, Elisa
Le Lay, Soazig
Lee, Myung-Shin
Lee, Yi Xin Fiona
Lemos, Debora S.
Lenassi, Metka
Leszczynska, Aleksandra
Li, Isaac T. S.
Liao, Ke
Libregts, Sten F.
Ligeti, Erzsebet
Lim, Rebecca
Lim, Sai Kiang
Linē, Aija
Linnemannstöns, Karen
Llorente, Alicia
Lombard, Catherine A.
Lorenowicz, Magdalena J.
Lörincz, Ákos M.
Lötvall, Jan
Lovett, Jason
Lowry, Michelle C.
Loyer, Xavier
Lu, Quan
Lukomska, Barbara
Lunavat, Taral R.
Maas, Sybren L. N.
Malhi, Harmeet
Marcilla, Antonio|||0000-0003-0004-0531
Mariani, Jacopo
Mariscal, Javier
Martens-Uzunova, Elena S.
Martin-Jaular, Lorena
Martinez, M. Carmen
Martins, Vilma Regina
Mathieu, Mathilde
Mathivanan, Suresh
Maugeri, Marco
McGinnis, Lynda K.
McVey, Mark J.
Meckes, David G.
Meehan, Katie L.
Mertens, Inge
Minciacchi, Valentina R.
Möller, Andreas
Møller Jørgensen, Malene
Morales-Kastresana, Aizea
Morhayim, Jess
Mullier, François
Muraca, Maurizio
Musante, Luca
Mussack, Veronika
Muth, Dillon C.
Myburgh, Kathryn H.
Najrana, Tanbir
Nawaz, Muhammad
Nazarenko, Irina
Nejsum, Peter
Neri, Christian
Neri, Tommaso
Nieuwland, Rienk
Nimrichter, Leonardo
Nolan, John P.
Nolte-'t Hoen, Esther N. M.
Noren Hooten, Nicole
O'Driscoll, Lorraine
O'Grady, Tina
O'Loghlen, Ana
Ochiya, Takahiro
Olivier, Martin
Ortiz, Alberto|||0000-0002-9805-9523
Ortiz, Luis A.
Osteikoetxea, Xabier
Østergaard, Ole
Ostrowski, Matias
Park, Jaesung
Pegtel, D. Michiel
Peinado, Héctor|||0000-0002-4256-3413
Perut, Francesca
Pfaffl, Michael W.
Phinney, Donald G.
Pieters, Bartijn C. H.
Pink, Ryan C.
Pisetsky, David S.
Pogge von Strandmann, Elke
Polakovicova, Iva
Poon, Ivan K. H.
Powell, Bonita H.
Prada, Ilaria
Pulliam, Lynn
Quesenberry, Peter
Radeghieri, Annalisa
Raffai, Robert L.
Raimondo, Stefania
Rak, Janusz
Ramirez, Marcel I.
Raposo, Graça
Rayyan, Morsi S.
Regev-Rudzki, Neta
Ricklefs, Franz L.
Robbins, Paul D.
Roberts, David D.
Rodrigues, Silvia C.
Rohde, Eva
Rome, Sophie
Rouschop, Kasper M. A.
Rughetti, Aurelia
Russell, Ashley E.
Saá, Paula
Sahoo, Susmita
Salas-Huenuleo, Edison
Sánchez, Catherine
Saugstad, Julie A.
Saul, Meike J.
Schiffelers, Raymond M.
Schneider, Raphael
Schøyen, Tine Hiorth
Scott, Aaron
Shahaj, Eriomina
Sharma, Shivani
Shatnyeva, Olga
Shekari, Faezeh
Shelke, Ganesh Vilas
Shetty, Ashok K.
Shiba, Kiyotaka
Siljander, Pia R-M.
Silva, Andreia M.
Skowronek, Agata
Snyder, Orman L.
Soares, Rodrigo Pedro
Sódar, Barbara W.
Soekmadji, Carolina
Sotillo, Javier
Stahl, Philip D.
Stoorvogel, Willem
Stott, Shannon L.
Strasser, Erwin F.
Swift, Simon
Tahara, Hidetoshi
Tewari, Muneesh
Timms, Kate
Tiwari, Swasti
Tixeira, Rochelle
Tkach, Mercedes
Toh, Wei Seong
Tomasini, Richard
Torrecilhas, Ana Claudia
Tosar, Juan Pablo
Toxavidis, Vasilis
Urbanelli, Lorena
Vader, Pieter
van Balkom, Bas W. M.
van der Grein, Susanne G.
Van Deun, Jan
van Herwijnen, Martijn J. C.
Van Keuren-Jensen, Kendall
van Niel, Guillaume
Van Royen, Martin E.
van Wijnen, Andre J.
Vasconcelos, M. Helena
Vechetti, Ivan J.
Veit, Tiago D.
Vella, Laura J.
Velot, Émilie
Verweij, Frederik J.
Vestad, Beate
Viñas, Jose L.
Visnovitz, Tamás
Vukman, Krisztina V.
Wahlgren, Jessica
Watson, Dionysios C.
Wauben, Marca H. M.
Weaver, Alissa
Webber, Jason P.
Weber, Viktoria
Wehman, Ann M.
Weiss, Daniel J.
Welsh, Joshua A.
Wendt, Sebastian
Wheelock, Asa M.
Wiener, Zoltán
Witte, Leonie
Wolfram, Joy
Xagorari, Angeliki
Xander, Patricia
Xu, Jing
Yan, Xiaomei
Yáñez-Mó, María|||0000-0001-7484-2866
Yin, Hang
Yuana, Yuana
Zappulli, Valentina
Zarubova, Jana
Žėkas, Vytautas
Zhang, Jian-ye
Zhao, Zezhou
Zheng, Lei
Zheutlin, Alexander R.
Zickler, Antje M.
Zimmermann, Pascale
Zivkovic, Angela M.
Zocco, Davide
Zuba-Surma, Ewa K.
author Théry, Clotilde|||0000-0001-8294-6884
author_facet Théry, Clotilde|||0000-0001-8294-6884
Witwer, Kenneth W.|||0000-0003-1664-4233
Aikawa, Elena
Alcaraz, Maria Jose
Anderson, Johnathon D.
Andriantsitohaina, Ramaroson
Antoniou, Anna
Arab, Tanina
Archer, Fabienne
Atkin-Smith, Georgia K.
Ayre, D. Craig
Bach, Jean-Marie
Bachurski, Daniel
Baharvand, Hossein
Balaj, Leonora
Baldacchino, Shawn
Bauer, Natalie N.
Baxter, Amy A.
Bebawy, Mary
Beckham, Carla
Bedina Zavec, Apolonija
Benmoussa, Abderrahim
Berardi, Anna C.
Bergese, Paolo
Bielska, Ewa
Blenkiron, Cherie
Bobis-Wozowicz, Sylwia
Boilard, Eric
Boireau, Wilfrid
Bongiovanni, Antonella
Borràs i Serres, Francesc Enric|||0000-0003-4038-1912
Bosch, Steffi
Boulanger, Chantal M.
Breakefield, Xandra
Breglio, Andrew M.
Brennan, Meadhbh Á.
Brigstock, David R.
Brisson, Alain
Broekman, Marike L. D.
Bromberg, Jacqueline F.
Bryl-Górecka, Paulina
Buch, Shilpa
Buck, Amy H.
Burger, Dylan
Busatto, Sara
Buschmann, Dominik
Bussolati, Benedetta
Buzás, Edit I.
Byrd, James Bryan
Camussi, Giovanni
Carter, David R. F.
Caruso, Sarah
Chamley, Lawrence W.
Chang, Yu-Ting
Chen, Chihchen
Chen, Shuai
Cheng, Lesley
Chin, Andrew R.
Clayton, Aled
Clerici, Stefano P.
Cocks, Alex
Cocucci, Emanuele
Coffey, Robert J.
Cordeiro-da-Silva, A.|||0000-0003-2392-6087
Couch, Yvonne
Coumans, Frank A. W.
Coyle, Beth
Crescitelli, Rossella
Criado, Miria Ferreira
D'Souza-Schorey, Crislyn
Das, Saumya
Datta Chaudhuri, Amrita
de Candia, Paola
De Santana, Eliezer F.
De Wever, Olivier
Del Portillo, Hernando A.|||0000-0002-5278-3452
Demaret, Tanguy
Deville, Sarah
Devitt, Andrew
Dhondt, Bert
Di Vizio, Dolores
Dieterich, Lothar C.
Dolo, Vincenza
Dominguez Rubio, Ana Paula
Dominici, Massimo
Dourado, Mauricio R.
Driedonks, Tom A. P.
Duarte, Filipe V.
Duncan, Heather M.
Eichenberger, Ramon M.
Ekström, Karin
E. L. Andaloussi, Samir
Elie-Caille, Celine
Erdbrügger, Uta
Falcón-Pérez, Juan M.|||0000-0003-3133-0670
Fatima, Farah
Fish, Jason E.
Flores-Bellver, Miguel
Försönits, András
Frelet-Barrand, Annie
Fricke, Fabia
Fuhrmann, Gregor
Gabrielsson, Susanne
Gámez-Valero, Ana|||0000-0002-9530-2751
Gardiner, Chris
Gärtner, Kathrin
Gaudin, Raphael
Gho, Yong Song
Giebel, Bernd
Gilbert, Caroline
Gimona, Mario
Giusti, Ilaria
Goberdhan, Deborah C. I.
Görgens, André
Gorski, Sharon M.
Greening, David W.
Gross, Julia Christina
Gualerzi, Alice
Gupta, Gopal N.
Gustafson, Dakota
Handberg, Aase
Haraszti, Reka A.
Harrison, Paul
Hegyesi, Hargita
Hendrix, An
Hill, Andrew F.
Hochberg, Fred H.
Hoffmann, Karl F.
Holder, Beth
Holthofer, Harry
Hosseinkhani, Baharak
Hu, Guoku
Huang, Yiyao
Huber, Veronica
Hunt, Stuart
Ibrahim, Ahmed Gamal-Eldin
Ikezu, Tsuneya
Inal, Jameel M.
Isin, Mustafa
Ivanova, Alena
Jackson, Hannah K.
Jacobsen, Søren
Jay, Steven M.
Jayachandran, Muthuvel
Jenster, Guido|||0000-0002-8658-2552
Jiang, Lanzhou
Johnson, Suzanne M.
Jones, Jennifer C.
Jong, Ambrose
Jovanovic-Talisman, Tijana
Jung, Stephanie
Kalluri, Raghu
Kano, Shin-ichi
Kaur, Sukhbir
Kawamura, Yumi
Keller, Evan T.
Khamari, Delaram
Khomyakova, Elena
Khvorova, Anastasia
Kierulf, Peter
Kim, Kwang Pyo
Kislinger, Thomas
Klingeborn, Mikael
Klinke, David J.
Kornek, Miroslaw
Kosanović, Maja M.
Kovács, Árpád Ferenc
Krämer-Albers, Eva-Maria
Krasemann, Susanne
Krause, Mirja
Kurochkin, Igor V.
Kusuma, Gina D.
Kuypers, Sören
Laitinen, Saara
Langevin, Scott M.
Languino, Lucia R.
Lannigan, Joanne
Lässer, Cecilia
Laurent, Louise C.
Lavieu, Gregory
Lázaro-Ibáñez, Elisa
Le Lay, Soazig
Lee, Myung-Shin
Lee, Yi Xin Fiona
Lemos, Debora S.
Lenassi, Metka
Leszczynska, Aleksandra
Li, Isaac T. S.
Liao, Ke
Libregts, Sten F.
Ligeti, Erzsebet
Lim, Rebecca
Lim, Sai Kiang
Linē, Aija
Linnemannstöns, Karen
Llorente, Alicia
Lombard, Catherine A.
Lorenowicz, Magdalena J.
Lörincz, Ákos M.
Lötvall, Jan
Lovett, Jason
Lowry, Michelle C.
Loyer, Xavier
Lu, Quan
Lukomska, Barbara
Lunavat, Taral R.
Maas, Sybren L. N.
Malhi, Harmeet
Marcilla, Antonio|||0000-0003-0004-0531
Mariani, Jacopo
Mariscal, Javier
Martens-Uzunova, Elena S.
Martin-Jaular, Lorena
Martinez, M. Carmen
Martins, Vilma Regina
Mathieu, Mathilde
Mathivanan, Suresh
Maugeri, Marco
McGinnis, Lynda K.
McVey, Mark J.
Meckes, David G.
Meehan, Katie L.
Mertens, Inge
Minciacchi, Valentina R.
Möller, Andreas
Møller Jørgensen, Malene
Morales-Kastresana, Aizea
Morhayim, Jess
Mullier, François
Muraca, Maurizio
Musante, Luca
Mussack, Veronika
Muth, Dillon C.
Myburgh, Kathryn H.
Najrana, Tanbir
Nawaz, Muhammad
Nazarenko, Irina
Nejsum, Peter
Neri, Christian
Neri, Tommaso
Nieuwland, Rienk
Nimrichter, Leonardo
Nolan, John P.
Nolte-'t Hoen, Esther N. M.
Noren Hooten, Nicole
O'Driscoll, Lorraine
O'Grady, Tina
O'Loghlen, Ana
Ochiya, Takahiro
Olivier, Martin
Ortiz, Alberto|||0000-0002-9805-9523
Ortiz, Luis A.
Osteikoetxea, Xabier
Østergaard, Ole
Ostrowski, Matias
Park, Jaesung
Pegtel, D. Michiel
Peinado, Héctor|||0000-0002-4256-3413
Perut, Francesca
Pfaffl, Michael W.
Phinney, Donald G.
Pieters, Bartijn C. H.
Pink, Ryan C.
Pisetsky, David S.
Pogge von Strandmann, Elke
Polakovicova, Iva
Poon, Ivan K. H.
Powell, Bonita H.
Prada, Ilaria
Pulliam, Lynn
Quesenberry, Peter
Radeghieri, Annalisa
Raffai, Robert L.
Raimondo, Stefania
Rak, Janusz
Ramirez, Marcel I.
Raposo, Graça
Rayyan, Morsi S.
Regev-Rudzki, Neta
Ricklefs, Franz L.
Robbins, Paul D.
Roberts, David D.
Rodrigues, Silvia C.
Rohde, Eva
Rome, Sophie
Rouschop, Kasper M. A.
Rughetti, Aurelia
Russell, Ashley E.
Saá, Paula
Sahoo, Susmita
Salas-Huenuleo, Edison
Sánchez, Catherine
Saugstad, Julie A.
Saul, Meike J.
Schiffelers, Raymond M.
Schneider, Raphael
Schøyen, Tine Hiorth
Scott, Aaron
Shahaj, Eriomina
Sharma, Shivani
Shatnyeva, Olga
Shekari, Faezeh
Shelke, Ganesh Vilas
Shetty, Ashok K.
Shiba, Kiyotaka
Siljander, Pia R-M.
Silva, Andreia M.
Skowronek, Agata
Snyder, Orman L.
Soares, Rodrigo Pedro
Sódar, Barbara W.
Soekmadji, Carolina
Sotillo, Javier
Stahl, Philip D.
Stoorvogel, Willem
Stott, Shannon L.
Strasser, Erwin F.
Swift, Simon
Tahara, Hidetoshi
Tewari, Muneesh
Timms, Kate
Tiwari, Swasti
Tixeira, Rochelle
Tkach, Mercedes
Toh, Wei Seong
Tomasini, Richard
Torrecilhas, Ana Claudia
Tosar, Juan Pablo
Toxavidis, Vasilis
Urbanelli, Lorena
Vader, Pieter
van Balkom, Bas W. M.
van der Grein, Susanne G.
Van Deun, Jan
van Herwijnen, Martijn J. C.
Van Keuren-Jensen, Kendall
van Niel, Guillaume
Van Royen, Martin E.
van Wijnen, Andre J.
Vasconcelos, M. Helena
Vechetti, Ivan J.
Veit, Tiago D.
Vella, Laura J.
Velot, Émilie
Verweij, Frederik J.
Vestad, Beate
Viñas, Jose L.
Visnovitz, Tamás
Vukman, Krisztina V.
Wahlgren, Jessica
Watson, Dionysios C.
Wauben, Marca H. M.
Weaver, Alissa
Webber, Jason P.
Weber, Viktoria
Wehman, Ann M.
Weiss, Daniel J.
Welsh, Joshua A.
Wendt, Sebastian
Wheelock, Asa M.
Wiener, Zoltán
Witte, Leonie
Wolfram, Joy
Xagorari, Angeliki
Xander, Patricia
Xu, Jing
Yan, Xiaomei
Yáñez-Mó, María|||0000-0001-7484-2866
Yin, Hang
Yuana, Yuana
Zappulli, Valentina
Zarubova, Jana
Žėkas, Vytautas
Zhang, Jian-ye
Zhao, Zezhou
Zheng, Lei
Zheutlin, Alexander R.
Zickler, Antje M.
Zimmermann, Pascale
Zivkovic, Angela M.
Zocco, Davide
Zuba-Surma, Ewa K.
author_role author
author2 Witwer, Kenneth W.|||0000-0003-1664-4233
Aikawa, Elena
Alcaraz, Maria Jose
Anderson, Johnathon D.
Andriantsitohaina, Ramaroson
Antoniou, Anna
Arab, Tanina
Archer, Fabienne
Atkin-Smith, Georgia K.
Ayre, D. Craig
Bach, Jean-Marie
Bachurski, Daniel
Baharvand, Hossein
Balaj, Leonora
Baldacchino, Shawn
Bauer, Natalie N.
Baxter, Amy A.
Bebawy, Mary
Beckham, Carla
Bedina Zavec, Apolonija
Benmoussa, Abderrahim
Berardi, Anna C.
Bergese, Paolo
Bielska, Ewa
Blenkiron, Cherie
Bobis-Wozowicz, Sylwia
Boilard, Eric
Boireau, Wilfrid
Bongiovanni, Antonella
Borràs i Serres, Francesc Enric|||0000-0003-4038-1912
Bosch, Steffi
Boulanger, Chantal M.
Breakefield, Xandra
Breglio, Andrew M.
Brennan, Meadhbh Á.
Brigstock, David R.
Brisson, Alain
Broekman, Marike L. D.
Bromberg, Jacqueline F.
Bryl-Górecka, Paulina
Buch, Shilpa
Buck, Amy H.
Burger, Dylan
Busatto, Sara
Buschmann, Dominik
Bussolati, Benedetta
Buzás, Edit I.
Byrd, James Bryan
Camussi, Giovanni
Carter, David R. F.
Caruso, Sarah
Chamley, Lawrence W.
Chang, Yu-Ting
Chen, Chihchen
Chen, Shuai
Cheng, Lesley
Chin, Andrew R.
Clayton, Aled
Clerici, Stefano P.
Cocks, Alex
Cocucci, Emanuele
Coffey, Robert J.
Cordeiro-da-Silva, A.|||0000-0003-2392-6087
Couch, Yvonne
Coumans, Frank A. W.
Coyle, Beth
Crescitelli, Rossella
Criado, Miria Ferreira
D'Souza-Schorey, Crislyn
Das, Saumya
Datta Chaudhuri, Amrita
de Candia, Paola
De Santana, Eliezer F.
De Wever, Olivier
Del Portillo, Hernando A.|||0000-0002-5278-3452
Demaret, Tanguy
Deville, Sarah
Devitt, Andrew
Dhondt, Bert
Di Vizio, Dolores
Dieterich, Lothar C.
Dolo, Vincenza
Dominguez Rubio, Ana Paula
Dominici, Massimo
Dourado, Mauricio R.
Driedonks, Tom A. P.
Duarte, Filipe V.
Duncan, Heather M.
Eichenberger, Ramon M.
Ekström, Karin
E. L. Andaloussi, Samir
Elie-Caille, Celine
Erdbrügger, Uta
Falcón-Pérez, Juan M.|||0000-0003-3133-0670
Fatima, Farah
Fish, Jason E.
Flores-Bellver, Miguel
Försönits, András
Frelet-Barrand, Annie
Fricke, Fabia
Fuhrmann, Gregor
Gabrielsson, Susanne
Gámez-Valero, Ana|||0000-0002-9530-2751
Gardiner, Chris
Gärtner, Kathrin
Gaudin, Raphael
Gho, Yong Song
Giebel, Bernd
Gilbert, Caroline
Gimona, Mario
Giusti, Ilaria
Goberdhan, Deborah C. I.
Görgens, André
Gorski, Sharon M.
Greening, David W.
Gross, Julia Christina
Gualerzi, Alice
Gupta, Gopal N.
Gustafson, Dakota
Handberg, Aase
Haraszti, Reka A.
Harrison, Paul
Hegyesi, Hargita
Hendrix, An
Hill, Andrew F.
Hochberg, Fred H.
Hoffmann, Karl F.
Holder, Beth
Holthofer, Harry
Hosseinkhani, Baharak
Hu, Guoku
Huang, Yiyao
Huber, Veronica
Hunt, Stuart
Ibrahim, Ahmed Gamal-Eldin
Ikezu, Tsuneya
Inal, Jameel M.
Isin, Mustafa
Ivanova, Alena
Jackson, Hannah K.
Jacobsen, Søren
Jay, Steven M.
Jayachandran, Muthuvel
Jenster, Guido|||0000-0002-8658-2552
Jiang, Lanzhou
Johnson, Suzanne M.
Jones, Jennifer C.
Jong, Ambrose
Jovanovic-Talisman, Tijana
Jung, Stephanie
Kalluri, Raghu
Kano, Shin-ichi
Kaur, Sukhbir
Kawamura, Yumi
Keller, Evan T.
Khamari, Delaram
Khomyakova, Elena
Khvorova, Anastasia
Kierulf, Peter
Kim, Kwang Pyo
Kislinger, Thomas
Klingeborn, Mikael
Klinke, David J.
Kornek, Miroslaw
Kosanović, Maja M.
Kovács, Árpád Ferenc
Krämer-Albers, Eva-Maria
Krasemann, Susanne
Krause, Mirja
Kurochkin, Igor V.
Kusuma, Gina D.
Kuypers, Sören
Laitinen, Saara
Langevin, Scott M.
Languino, Lucia R.
Lannigan, Joanne
Lässer, Cecilia
Laurent, Louise C.
Lavieu, Gregory
Lázaro-Ibáñez, Elisa
Le Lay, Soazig
Lee, Myung-Shin
Lee, Yi Xin Fiona
Lemos, Debora S.
Lenassi, Metka
Leszczynska, Aleksandra
Li, Isaac T. S.
Liao, Ke
Libregts, Sten F.
Ligeti, Erzsebet
Lim, Rebecca
Lim, Sai Kiang
Linē, Aija
Linnemannstöns, Karen
Llorente, Alicia
Lombard, Catherine A.
Lorenowicz, Magdalena J.
Lörincz, Ákos M.
Lötvall, Jan
Lovett, Jason
Lowry, Michelle C.
Loyer, Xavier
Lu, Quan
Lukomska, Barbara
Lunavat, Taral R.
Maas, Sybren L. N.
Malhi, Harmeet
Marcilla, Antonio|||0000-0003-0004-0531
Mariani, Jacopo
Mariscal, Javier
Martens-Uzunova, Elena S.
Martin-Jaular, Lorena
Martinez, M. Carmen
Martins, Vilma Regina
Mathieu, Mathilde
Mathivanan, Suresh
Maugeri, Marco
McGinnis, Lynda K.
McVey, Mark J.
Meckes, David G.
Meehan, Katie L.
Mertens, Inge
Minciacchi, Valentina R.
Möller, Andreas
Møller Jørgensen, Malene
Morales-Kastresana, Aizea
Morhayim, Jess
Mullier, François
Muraca, Maurizio
Musante, Luca
Mussack, Veronika
Muth, Dillon C.
Myburgh, Kathryn H.
Najrana, Tanbir
Nawaz, Muhammad
Nazarenko, Irina
Nejsum, Peter
Neri, Christian
Neri, Tommaso
Nieuwland, Rienk
Nimrichter, Leonardo
Nolan, John P.
Nolte-'t Hoen, Esther N. M.
Noren Hooten, Nicole
O'Driscoll, Lorraine
O'Grady, Tina
O'Loghlen, Ana
Ochiya, Takahiro
Olivier, Martin
Ortiz, Alberto|||0000-0002-9805-9523
Ortiz, Luis A.
Osteikoetxea, Xabier
Østergaard, Ole
Ostrowski, Matias
Park, Jaesung
Pegtel, D. Michiel
Peinado, Héctor|||0000-0002-4256-3413
Perut, Francesca
Pfaffl, Michael W.
Phinney, Donald G.
Pieters, Bartijn C. H.
Pink, Ryan C.
Pisetsky, David S.
Pogge von Strandmann, Elke
Polakovicova, Iva
Poon, Ivan K. H.
Powell, Bonita H.
Prada, Ilaria
Pulliam, Lynn
Quesenberry, Peter
Radeghieri, Annalisa
Raffai, Robert L.
Raimondo, Stefania
Rak, Janusz
Ramirez, Marcel I.
Raposo, Graça
Rayyan, Morsi S.
Regev-Rudzki, Neta
Ricklefs, Franz L.
Robbins, Paul D.
Roberts, David D.
Rodrigues, Silvia C.
Rohde, Eva
Rome, Sophie
Rouschop, Kasper M. A.
Rughetti, Aurelia
Russell, Ashley E.
Saá, Paula
Sahoo, Susmita
Salas-Huenuleo, Edison
Sánchez, Catherine
Saugstad, Julie A.
Saul, Meike J.
Schiffelers, Raymond M.
Schneider, Raphael
Schøyen, Tine Hiorth
Scott, Aaron
Shahaj, Eriomina
Sharma, Shivani
Shatnyeva, Olga
Shekari, Faezeh
Shelke, Ganesh Vilas
Shetty, Ashok K.
Shiba, Kiyotaka
Siljander, Pia R-M.
Silva, Andreia M.
Skowronek, Agata
Snyder, Orman L.
Soares, Rodrigo Pedro
Sódar, Barbara W.
Soekmadji, Carolina
Sotillo, Javier
Stahl, Philip D.
Stoorvogel, Willem
Stott, Shannon L.
Strasser, Erwin F.
Swift, Simon
Tahara, Hidetoshi
Tewari, Muneesh
Timms, Kate
Tiwari, Swasti
Tixeira, Rochelle
Tkach, Mercedes
Toh, Wei Seong
Tomasini, Richard
Torrecilhas, Ana Claudia
Tosar, Juan Pablo
Toxavidis, Vasilis
Urbanelli, Lorena
Vader, Pieter
van Balkom, Bas W. M.
van der Grein, Susanne G.
Van Deun, Jan
van Herwijnen, Martijn J. C.
Van Keuren-Jensen, Kendall
van Niel, Guillaume
Van Royen, Martin E.
van Wijnen, Andre J.
Vasconcelos, M. Helena
Vechetti, Ivan J.
Veit, Tiago D.
Vella, Laura J.
Velot, Émilie
Verweij, Frederik J.
Vestad, Beate
Viñas, Jose L.
Visnovitz, Tamás
Vukman, Krisztina V.
Wahlgren, Jessica
Watson, Dionysios C.
Wauben, Marca H. M.
Weaver, Alissa
Webber, Jason P.
Weber, Viktoria
Wehman, Ann M.
Weiss, Daniel J.
Welsh, Joshua A.
Wendt, Sebastian
Wheelock, Asa M.
Wiener, Zoltán
Witte, Leonie
Wolfram, Joy
Xagorari, Angeliki
Xander, Patricia
Xu, Jing
Yan, Xiaomei
Yáñez-Mó, María|||0000-0001-7484-2866
Yin, Hang
Yuana, Yuana
Zappulli, Valentina
Zarubova, Jana
Žėkas, Vytautas
Zhang, Jian-ye
Zhao, Zezhou
Zheng, Lei
Zheutlin, Alexander R.
Zickler, Antje M.
Zimmermann, Pascale
Zivkovic, Angela M.
Zocco, Davide
Zuba-Surma, Ewa K.
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dc.subject.none.fl_str_mv Extracellular vesicles
Exosomes
Ectosomes
Microvesicles
Minimal information requirements
Guidelines
Standardization
Microparticles
Rigor
Reproducibility
topic Extracellular vesicles
Exosomes
Ectosomes
Microvesicles
Minimal information requirements
Guidelines
Standardization
Microparticles
Rigor
Reproducibility
description The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles ("MISEV") guidelines for the field in 2014. We now update these "MISEV2014" guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities. Finally, a checklist is provided with summaries of key points.
publishDate 2018
dc.date.none.fl_str_mv 2
2018-01-01
2018
2018-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/253238
https://dx.doi.org/urn:doi:10.1080/20013078.2018.1535750
url https://ddd.uab.cat/record/253238
https://dx.doi.org/urn:doi:10.1080/20013078.2018.1535750
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869410190907932672
spelling Minimal information for studies of extracellular vesicles 2018 (MISEV2018)a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelinesThéry, Clotilde|||0000-0001-8294-6884Witwer, Kenneth W.|||0000-0003-1664-4233Aikawa, ElenaAlcaraz, Maria JoseAnderson, Johnathon D.Andriantsitohaina, RamarosonAntoniou, AnnaArab, TaninaArcher, FabienneAtkin-Smith, Georgia K.Ayre, D. CraigBach, Jean-MarieBachurski, DanielBaharvand, HosseinBalaj, LeonoraBaldacchino, ShawnBauer, Natalie N.Baxter, Amy A.Bebawy, MaryBeckham, CarlaBedina Zavec, ApolonijaBenmoussa, AbderrahimBerardi, Anna C.Bergese, PaoloBielska, EwaBlenkiron, CherieBobis-Wozowicz, SylwiaBoilard, EricBoireau, WilfridBongiovanni, AntonellaBorràs i Serres, Francesc Enric|||0000-0003-4038-1912Bosch, SteffiBoulanger, Chantal M.Breakefield, XandraBreglio, Andrew M.Brennan, Meadhbh Á.Brigstock, David R.Brisson, AlainBroekman, Marike L. D.Bromberg, Jacqueline F.Bryl-Górecka, PaulinaBuch, ShilpaBuck, Amy H.Burger, DylanBusatto, SaraBuschmann, DominikBussolati, BenedettaBuzás, Edit I.Byrd, James BryanCamussi, GiovanniCarter, David R. F.Caruso, SarahChamley, Lawrence W.Chang, Yu-TingChen, ChihchenChen, ShuaiCheng, LesleyChin, Andrew R.Clayton, AledClerici, Stefano P.Cocks, AlexCocucci, EmanueleCoffey, Robert J.Cordeiro-da-Silva, A.|||0000-0003-2392-6087Couch, YvonneCoumans, Frank A. W.Coyle, BethCrescitelli, RossellaCriado, Miria FerreiraD'Souza-Schorey, CrislynDas, SaumyaDatta Chaudhuri, Amritade Candia, PaolaDe Santana, Eliezer F.De Wever, OlivierDel Portillo, Hernando A.|||0000-0002-5278-3452Demaret, TanguyDeville, SarahDevitt, AndrewDhondt, BertDi Vizio, DoloresDieterich, Lothar C.Dolo, VincenzaDominguez Rubio, Ana PaulaDominici, MassimoDourado, Mauricio R.Driedonks, Tom A. P.Duarte, Filipe V.Duncan, Heather M.Eichenberger, Ramon M.Ekström, KarinE. L. Andaloussi, SamirElie-Caille, CelineErdbrügger, UtaFalcón-Pérez, Juan M.|||0000-0003-3133-0670Fatima, FarahFish, Jason E.Flores-Bellver, MiguelFörsönits, AndrásFrelet-Barrand, AnnieFricke, FabiaFuhrmann, GregorGabrielsson, SusanneGámez-Valero, Ana|||0000-0002-9530-2751Gardiner, ChrisGärtner, KathrinGaudin, RaphaelGho, Yong SongGiebel, BerndGilbert, CarolineGimona, MarioGiusti, IlariaGoberdhan, Deborah C. I.Görgens, AndréGorski, Sharon M.Greening, David W.Gross, Julia ChristinaGualerzi, AliceGupta, Gopal N.Gustafson, DakotaHandberg, AaseHaraszti, Reka A.Harrison, PaulHegyesi, HargitaHendrix, AnHill, Andrew F.Hochberg, Fred H.Hoffmann, Karl F.Holder, BethHolthofer, HarryHosseinkhani, BaharakHu, GuokuHuang, YiyaoHuber, VeronicaHunt, StuartIbrahim, Ahmed Gamal-EldinIkezu, TsuneyaInal, Jameel M.Isin, MustafaIvanova, AlenaJackson, Hannah K.Jacobsen, SørenJay, Steven M.Jayachandran, MuthuvelJenster, Guido|||0000-0002-8658-2552Jiang, LanzhouJohnson, Suzanne M.Jones, Jennifer C.Jong, AmbroseJovanovic-Talisman, TijanaJung, StephanieKalluri, RaghuKano, Shin-ichiKaur, SukhbirKawamura, YumiKeller, Evan T.Khamari, DelaramKhomyakova, ElenaKhvorova, AnastasiaKierulf, PeterKim, Kwang PyoKislinger, ThomasKlingeborn, MikaelKlinke, David J.Kornek, MiroslawKosanović, Maja M.Kovács, Árpád FerencKrämer-Albers, Eva-MariaKrasemann, SusanneKrause, MirjaKurochkin, Igor V.Kusuma, Gina D.Kuypers, SörenLaitinen, SaaraLangevin, Scott M.Languino, Lucia R.Lannigan, JoanneLässer, CeciliaLaurent, Louise C.Lavieu, GregoryLázaro-Ibáñez, ElisaLe Lay, SoazigLee, Myung-ShinLee, Yi Xin FionaLemos, Debora S.Lenassi, MetkaLeszczynska, AleksandraLi, Isaac T. S.Liao, KeLibregts, Sten F.Ligeti, ErzsebetLim, RebeccaLim, Sai KiangLinē, AijaLinnemannstöns, KarenLlorente, AliciaLombard, Catherine A.Lorenowicz, Magdalena J.Lörincz, Ákos M.Lötvall, JanLovett, JasonLowry, Michelle C.Loyer, XavierLu, QuanLukomska, BarbaraLunavat, Taral R.Maas, Sybren L. N.Malhi, HarmeetMarcilla, Antonio|||0000-0003-0004-0531Mariani, JacopoMariscal, JavierMartens-Uzunova, Elena S.Martin-Jaular, LorenaMartinez, M. CarmenMartins, Vilma ReginaMathieu, MathildeMathivanan, SureshMaugeri, MarcoMcGinnis, Lynda K.McVey, Mark J.Meckes, David G.Meehan, Katie L.Mertens, IngeMinciacchi, Valentina R.Möller, AndreasMøller Jørgensen, MaleneMorales-Kastresana, AizeaMorhayim, JessMullier, FrançoisMuraca, MaurizioMusante, LucaMussack, VeronikaMuth, Dillon C.Myburgh, Kathryn H.Najrana, TanbirNawaz, MuhammadNazarenko, IrinaNejsum, PeterNeri, ChristianNeri, TommasoNieuwland, RienkNimrichter, LeonardoNolan, John P.Nolte-'t Hoen, Esther N. M.Noren Hooten, NicoleO'Driscoll, LorraineO'Grady, TinaO'Loghlen, AnaOchiya, TakahiroOlivier, MartinOrtiz, Alberto|||0000-0002-9805-9523Ortiz, Luis A.Osteikoetxea, XabierØstergaard, OleOstrowski, MatiasPark, JaesungPegtel, D. MichielPeinado, Héctor|||0000-0002-4256-3413Perut, FrancescaPfaffl, Michael W.Phinney, Donald G.Pieters, Bartijn C. H.Pink, Ryan C.Pisetsky, David S.Pogge von Strandmann, ElkePolakovicova, IvaPoon, Ivan K. H.Powell, Bonita H.Prada, IlariaPulliam, LynnQuesenberry, PeterRadeghieri, AnnalisaRaffai, Robert L.Raimondo, StefaniaRak, JanuszRamirez, Marcel I.Raposo, GraçaRayyan, Morsi S.Regev-Rudzki, NetaRicklefs, Franz L.Robbins, Paul D.Roberts, David D.Rodrigues, Silvia C.Rohde, EvaRome, SophieRouschop, Kasper M. A.Rughetti, AureliaRussell, Ashley E.Saá, PaulaSahoo, SusmitaSalas-Huenuleo, EdisonSánchez, CatherineSaugstad, Julie A.Saul, Meike J.Schiffelers, Raymond M.Schneider, RaphaelSchøyen, Tine HiorthScott, AaronShahaj, EriominaSharma, ShivaniShatnyeva, OlgaShekari, FaezehShelke, Ganesh VilasShetty, Ashok K.Shiba, KiyotakaSiljander, Pia R-M.Silva, Andreia M.Skowronek, AgataSnyder, Orman L.Soares, Rodrigo PedroSódar, Barbara W.Soekmadji, CarolinaSotillo, JavierStahl, Philip D.Stoorvogel, WillemStott, Shannon L.Strasser, Erwin F.Swift, SimonTahara, HidetoshiTewari, MuneeshTimms, KateTiwari, SwastiTixeira, RochelleTkach, MercedesToh, Wei SeongTomasini, RichardTorrecilhas, Ana ClaudiaTosar, Juan PabloToxavidis, VasilisUrbanelli, LorenaVader, Pietervan Balkom, Bas W. M.van der Grein, Susanne G.Van Deun, Janvan Herwijnen, Martijn J. C.Van Keuren-Jensen, Kendallvan Niel, GuillaumeVan Royen, Martin E.van Wijnen, Andre J.Vasconcelos, M. HelenaVechetti, Ivan J.Veit, Tiago D.Vella, Laura J.Velot, ÉmilieVerweij, Frederik J.Vestad, BeateViñas, Jose L.Visnovitz, TamásVukman, Krisztina V.Wahlgren, JessicaWatson, Dionysios C.Wauben, Marca H. M.Weaver, AlissaWebber, Jason P.Weber, ViktoriaWehman, Ann M.Weiss, Daniel J.Welsh, Joshua A.Wendt, SebastianWheelock, Asa M.Wiener, ZoltánWitte, LeonieWolfram, JoyXagorari, AngelikiXander, PatriciaXu, JingYan, XiaomeiYáñez-Mó, María|||0000-0001-7484-2866Yin, HangYuana, YuanaZappulli, ValentinaZarubova, JanaŽėkas, VytautasZhang, Jian-yeZhao, ZezhouZheng, LeiZheutlin, Alexander R.Zickler, Antje M.Zimmermann, PascaleZivkovic, Angela M.Zocco, DavideZuba-Surma, Ewa K.Extracellular vesiclesExosomesEctosomesMicrovesiclesMinimal information requirementsGuidelinesStandardizationMicroparticlesRigorReproducibilityThe last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles ("MISEV") guidelines for the field in 2014. We now update these "MISEV2014" guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities. Finally, a checklist is provided with summaries of key points. 22018-01-0120182018-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/253238https://dx.doi.org/urn:doi:10.1080/20013078.2018.1535750reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2532382026-06-06T12:50:31Z
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