(1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.

9 p.

Detalles Bibliográficos
Autores: Ippel, Hans, Berbís, Manuel Álvaro, Cañada, F. Javier, Jiménez-Barbero, Jesús, Mayo, Kevin H.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/99242
Acceso en línea:http://hdl.handle.net/10261/99242
Access Level:acceso abierto
Palabra clave:Apoptosis
Galectin
Glycan
Proliferation
Signaling
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spelling (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.Ippel, HansBerbís, Manuel ÁlvaroCañada, F. JavierJiménez-Barbero, JesúsMayo, Kevin H.ApoptosisGalectinGlycanProliferationSignaling9 p.Galectin-3 has a unique trimodular design consisting of the canonical lectin domain, a collagen-like tandem-repeat section and an N-terminal peptide with two sites for Ser phosphorylation. Structural characterization of the full-length protein with its non-lectin part (115 of 250 residues) will help understand the multifunctionality of this potent cellular effector. Here, we report 1H, 13C, and 15N chemical shift assignments as determined by heteronuclear NMR spectroscopy.This work was generously supported by a research grant from the National Cancer Institute (CA-096090) to KHM; EC funding (GlycoHIT, contract no. 260600; GLYCOPHARM, contract no. 217297) to JJB & HJG, and European Research Council funding (ERC AdG °249929) to CW. NMR instrumentation was provided with funds from the National Science Foundation (BIR-961477), the University of Minnesota Medical School, and the Minnesota Medical Foundation.Peer reviewedSpringer Nature201420142014info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/99242reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1007/s12104-014-9545-3info:eu-repo/semantics/openAccessoai:digital.csic.es:10261/992422026-05-22T06:33:51Z
dc.title.none.fl_str_mv (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
title (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
spellingShingle (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
Ippel, Hans
Apoptosis
Galectin
Glycan
Proliferation
Signaling
title_short (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
title_full (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
title_fullStr (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
title_full_unstemmed (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
title_sort (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3.
dc.creator.none.fl_str_mv Ippel, Hans
Berbís, Manuel Álvaro
Cañada, F. Javier
Jiménez-Barbero, Jesús
Mayo, Kevin H.
author Ippel, Hans
author_facet Ippel, Hans
Berbís, Manuel Álvaro
Cañada, F. Javier
Jiménez-Barbero, Jesús
Mayo, Kevin H.
author_role author
author2 Berbís, Manuel Álvaro
Cañada, F. Javier
Jiménez-Barbero, Jesús
Mayo, Kevin H.
author2_role author
author
author
author
dc.subject.none.fl_str_mv Apoptosis
Galectin
Glycan
Proliferation
Signaling
topic Apoptosis
Galectin
Glycan
Proliferation
Signaling
description 9 p.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014
2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/99242
url http://hdl.handle.net/10261/99242
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1007/s12104-014-9545-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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