Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain

Toxoplasma gondii is an apicomplexan parasite globally distributed with a heteroxenous life cycle that virtually comprises all homoeothermic animals, including humans, as intermediate hosts and felids as definitive hosts. The zoonotic, abortifacient, and foodborne nature of the parasite makes toxopl...

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Autor: Fernández Escobar, Mercedes
Tipo de recurso: tesis doctoral
Fecha de publicación:2022
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/3462
Acceso en línea:https://hdl.handle.net/20.500.14352/3462
Access Level:acceso abierto
Palabra clave:576.89(043.2)
Veterinary parasitology
Parasitología veterinaria
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spelling Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in SpainCaracterización genética y fenotípica de aislados de Toxoplasma gondii obtenidos de ganado ovino y cerdo ibérico en EspañaFernández Escobar, Mercedes576.89(043.2)Veterinary parasitologyParasitología veterinariaToxoplasma gondii is an apicomplexan parasite globally distributed with a heteroxenous life cycle that virtually comprises all homoeothermic animals, including humans, as intermediate hosts and felids as definitive hosts. The zoonotic, abortifacient, and foodborne nature of the parasite makes toxoplasmosis a relevant public and animal health concern worldwide.A comprehensive research effort on T. gondii biology along with the rapid development of molecular techniques suitable for strains genotyping over the last decades, led to the initial description of a widely clonal European and North American T. gondii genetic population dominated by three main clonal genetic types (I, II, and III), in contrast to an extremely diverse South American population. However, the information available from Europe is limited, with frequent methodological deficiencies and important sampling disparities among regions. Briefly, the available European literature evidences a clear predominance of type II strains (comprising around 80% of samples) coexisting with much less abundant type III and recombinant strains or mixed infections, as well as minor proportions of type I and imported genotypes. In the specific case of Spain, the majority of the scarce investigations dealt with direct genotyping from clinical samples, with the subsequent limitations to classify the strains and the impossibility of extending its characterization...Universidad Complutense de MadridOrtega Mora, Luis MiguelCollantes Fernández, EstherCalero Bernal, RafaelUniversidad Complutense de Madrid20222022-02-1720222022-02-17doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/20.500.14352/3462reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/34622026-06-02T12:44:21Z
dc.title.none.fl_str_mv Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
Caracterización genética y fenotípica de aislados de Toxoplasma gondii obtenidos de ganado ovino y cerdo ibérico en España
title Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
spellingShingle Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
Fernández Escobar, Mercedes
576.89(043.2)
Veterinary parasitology
Parasitología veterinaria
title_short Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
title_full Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
title_fullStr Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
title_full_unstemmed Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
title_sort Genetic and phenotypic characterization of Toxoplasma gondii isolates obtained from sheep and Iberian pigs in Spain
dc.creator.none.fl_str_mv Fernández Escobar, Mercedes
author Fernández Escobar, Mercedes
author_facet Fernández Escobar, Mercedes
author_role author
dc.contributor.none.fl_str_mv Ortega Mora, Luis Miguel
Collantes Fernández, Esther
Calero Bernal, Rafael
Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 576.89(043.2)
Veterinary parasitology
Parasitología veterinaria
topic 576.89(043.2)
Veterinary parasitology
Parasitología veterinaria
description Toxoplasma gondii is an apicomplexan parasite globally distributed with a heteroxenous life cycle that virtually comprises all homoeothermic animals, including humans, as intermediate hosts and felids as definitive hosts. The zoonotic, abortifacient, and foodborne nature of the parasite makes toxoplasmosis a relevant public and animal health concern worldwide.A comprehensive research effort on T. gondii biology along with the rapid development of molecular techniques suitable for strains genotyping over the last decades, led to the initial description of a widely clonal European and North American T. gondii genetic population dominated by three main clonal genetic types (I, II, and III), in contrast to an extremely diverse South American population. However, the information available from Europe is limited, with frequent methodological deficiencies and important sampling disparities among regions. Briefly, the available European literature evidences a clear predominance of type II strains (comprising around 80% of samples) coexisting with much less abundant type III and recombinant strains or mixed infections, as well as minor proportions of type I and imported genotypes. In the specific case of Spain, the majority of the scarce investigations dealt with direct genotyping from clinical samples, with the subsequent limitations to classify the strains and the impossibility of extending its characterization...
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-02-17
2022
2022-02-17
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/3462
url https://hdl.handle.net/20.500.14352/3462
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Complutense de Madrid
publisher.none.fl_str_mv Universidad Complutense de Madrid
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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