Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae

15 p.-3 fig.-2 tab.

Detalles Bibliográficos
Autores: Sotillo, Alma, Pedrero, María, de Pablos, Manuela, García, José Luis, García, Ernesto, García González, Pedro, Pingarrón, José Manuel, Mingorance, Jesús, Campuzano, Susana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/99409
Acceso en línea:http://hdl.handle.net/10261/99409
Access Level:acceso abierto
Palabra clave:Streptococcus pneumoniae
Streptococcus mitis group
Biosensors
LytA gene
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spelling Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniaeSotillo, AlmaPedrero, Maríade Pablos, ManuelaGarcía, José LuisGarcía, ErnestoGarcía González, PedroPingarrón, José ManuelMingorance, JesúsCampuzano, SusanaStreptococcus pneumoniaeStreptococcus mitis groupBiosensorsLytA gene15 p.-3 fig.-2 tab.A disposable PCR-based amperometric magneto-genosensor for detection and identification of Streptococcus pneumoniae was evaluated. ROC curve analysis used to determine optimal signal cutoff values yielded a sensitivity of 91 % and a specificity of 90 %. The method was also tested for the direct detection of pneumococci in clinical samples.This work was funded by a grant from the Ministerio de Ciencia e Innovación (IPT-2011-1337-010000). CIBER de Enfermedades Respiratorias (CIBERES) is an initiative of the Instituto de Salud Carlos III. The financial support of the AVANSENS Program from the Comunidad de Madrid (S2009PPQ-1642) is gratefully acknowledged.Peer reviewedElsevierConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2014info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/99409reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1016/j.mimet.2014.04.014Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/994092026-05-22T06:33:51Z
dc.title.none.fl_str_mv Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
title Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
spellingShingle Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
Sotillo, Alma
Streptococcus pneumoniae
Streptococcus mitis group
Biosensors
LytA gene
title_short Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
title_full Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
title_fullStr Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
title_full_unstemmed Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
title_sort Clinical evaluation of a disposable amperometric magneto-genosensor for the detection and identification of Streptococcus pneumoniae
dc.creator.none.fl_str_mv Sotillo, Alma
Pedrero, María
de Pablos, Manuela
García, José Luis
García, Ernesto
García González, Pedro
Pingarrón, José Manuel
Mingorance, Jesús
Campuzano, Susana
author Sotillo, Alma
author_facet Sotillo, Alma
Pedrero, María
de Pablos, Manuela
García, José Luis
García, Ernesto
García González, Pedro
Pingarrón, José Manuel
Mingorance, Jesús
Campuzano, Susana
author_role author
author2 Pedrero, María
de Pablos, Manuela
García, José Luis
García, Ernesto
García González, Pedro
Pingarrón, José Manuel
Mingorance, Jesús
Campuzano, Susana
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Streptococcus pneumoniae
Streptococcus mitis group
Biosensors
LytA gene
topic Streptococcus pneumoniae
Streptococcus mitis group
Biosensors
LytA gene
description 15 p.-3 fig.-2 tab.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/99409
url http://hdl.handle.net/10261/99409
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1016/j.mimet.2014.04.014
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,198674

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