Compliance with Guidelines-Recommended Processes in Pneumonia: Impact of Health Status and Initial Signs

Initial care has been associated with improved survival of community-acquired pneumonia (CAP). We aimed to investigate patient comorbidities and health status measured by the Charlson index and clinical signs at diagnosis associated with adherence to recommended processes of care in CAP. We studied...

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Detalles Bibliográficos
Autores: Menéndez, Rosario, Torres Martí, Antoni, Reyes, Soledad, Zalacaín, Rafael, Capelastegui, Alberto, Rajas, Olga, Borderías, Luis, Martín Villasclaras, Juan J., Bello, Salvador, Alfageme, Inmaculada, Rodríguez de Castro, Felipe, Rello Condomines, Jordi, Molinos, Luis, Ruiz Manzano, Juan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:España
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/175500
Acceso en línea:https://hdl.handle.net/2445/175500
Access Level:acceso abierto
Palabra clave:Malalties pulmonars obstructives cròniques
Antibiòtics
Oxigen
Pneumònia
Taquicàrdia
Chronic obstructive pulmonary diseases
Antibiotics
Oxygen
Pneumonia
Tachycardia
Descripción
Sumario:Initial care has been associated with improved survival of community-acquired pneumonia (CAP). We aimed to investigate patient comorbidities and health status measured by the Charlson index and clinical signs at diagnosis associated with adherence to recommended processes of care in CAP. We studied 3844 patients hospitalized with CAP. The evaluated recommendations were antibiotic adherence to Spanish guidelines, first antibiotic dose <6 hours and oxygen assessment. Antibiotic adherence was 72.6%, first dose <6 h was 73.4% and oxygen assessment was 90.2%. Antibiotic adherence was negatively associated with a high Charlson score (Odds ratio [OR], 0.91), confusion (OR, 0.66) and tachycardia ≥100 bpm (OR, 0.77). Delayed first dose was significantly lower in those with tachycardia (OR, 0.75). Initial oxygen assessment was negatively associated with fever (OR, 0.61), whereas tachypnea ≥30 (OR, 1.58), tachycardia (OR, 1.39), age >65 (OR, 1.51) and COPD (OR, 1.80) were protective factors. The combination of antibiotic adherence and timing <6 hours was negatively associated with confusion (OR, 0.69) and a high Charlson score (OR, 0.92) adjusting for severity and hospital effect, whereas age was not an independent factor. Deficient health status and confusion, rather than age, are associated with lower compliance with antibiotic therapy recommendations and timing, thus identifying a subpopulation more prone to receiving lower quality care.