Low-strain effective Young's modulus model and validation for multi-layer vocal fold based silicone specimens with inclusions
A model of the effective low-strain elastic Young's modulus of multi-layer stacked composites is proposed, which is capable to account for an arbitrary stacked inclusion. Geometrical and discretization-based model results are validated against measured effective Young's moduli (from 10 up...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/194988 |
| Acceso en línea: | https://hdl.handle.net/2445/194988 |
| Access Level: | acceso abierto |
| Palabra clave: | Patologia Anàlisi de regressió Pathology Regression analysis |
| Sumario: | A model of the effective low-strain elastic Young's modulus of multi-layer stacked composites is proposed, which is capable to account for an arbitrary stacked inclusion. Geometrical and discretization-based model results are validated against measured effective Young's moduli (from 10 up to 40 kPa) on 14 molded silicone specimens embedding a stiff (298 kPa) inclusion with variable size, position, and stacking. Specimens without inclusion represent the muscle, superficial, and epithelium layers in a human vocal fold with Young's moduli between 4 and 65 kPa. The proposed model allows to predict the influence of a stiff inclusion, mimicking a structural abnormality or pathology somewhere within the vocal fold, on the low-strain effective Young's modulus. Quantifying the influence of an inclusion or local stiffening on the vocal fold bio-mechanics is a necessary step toward the understanding and mitigation of structural vocal fold pathologies and associated voice disorders. |
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