Rapid antigen tests for the detection of SARS-CoV-2: A narrative review

The rapid identificationand isolation of COVID-19 patients has become the cornerstone for the control of the recent outbreak. Real-time quantitative polymerase chain reaction is routinely used to confirm COVID-19 diagnosis and is considered the gold standard due to high sensitivity and specificity....

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Detalles Bibliográficos
Autores: Aguilar-Shea, Antonio L., Vera-García, Mar, Güerri Fernández, Roberto
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/51902
Acceso en línea:http://hdl.handle.net/10230/51902
http://dx.doi.org/10.1016/j.aprim.2021.102127
Access Level:acceso abierto
Palabra clave:Antigen test
COVID-19
Centró de atención médica
Diagnosis
Diagnóstico
Point-of-care
Rapid
Rápido
SARS-CoV-2
Test de antígenos
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spelling Rapid antigen tests for the detection of SARS-CoV-2: A narrative reviewTest rápidos de antígenos para la detección del SARS-CoV-2: Revisión narrativaAguilar-Shea, Antonio L.Vera-García, MarGüerri Fernández, RobertoAntigen testCOVID-19Centró de atención médicaDiagnosisDiagnósticoPoint-of-careRapidRápidoSARS-CoV-2Test de antígenosThe rapid identificationand isolation of COVID-19 patients has become the cornerstone for the control of the recent outbreak. Real-time quantitative polymerase chain reaction is routinely used to confirm COVID-19 diagnosis and is considered the gold standard due to high sensitivity and specificity. Nevertheless, it usually takes several days and a relatively higher cost. Antigen tests based have emerged to cope with such disadvantages, by offering rapid results, an easy-to-use procedure, and low costs. The objective of the narrative review was to provide up-to-date data about CE-marked rapid antigen tests (RATs) for COVID-19. Given their large number, the study only focused on representative and widely used in Spain (Standard Q, Nadal, Panbio, CerTest, and Wondfo). RATs have become a very useful and validated tool for controlling the spread of COVID-19 allowing the rapid identification of active infection and isolation of positive patients. The present revision of the literature has demonstrated that sensitivity and specificity of all available RATs in Spain are high and accomplish European regulations and WHO recommendations.La rápida identificación y aislamiento de los pacientes por COVID-19 se ha convertido en un reto para el control de la pandemia. La reacción en cadena de la polimerasa cuantitativa a tiempo real se utiliza de manera rutinaria para confirmar el diagnóstico de COVID-19 y se considera el estándar de referencia por su alta sensibilidad y especificidad. Sin embargo, normalmente lleva varios días y los costes son relativamente altos. Los test de antígeno son una herramienta rápida, fácil de realizar y de bajo coste. El objetivo de la revisión narrativa es proporcionar información actualizada sobre los test rápidos de antígenos (TRA) para COVID-19 con marcado europeo. Dado su gran número, el estudio solo se enfoca en aquellos representativos y ampliamente empleados en España (Standard Q, Nadal, Panbio, CerTest y Wondfo). Los TRA se han convertido en una herramienta validada muy útil para controlar la diseminación de la COVID-19, al permitir la identificación rápida de la infección activa y el aislamiento de pacientes positivos. La presente revisión de la literatura ha demostrado que la sensibilidad y especificidad de los TRA disponibles en España son altas y cumplen con la regulación europea y las recomendaciones de la OMS.Elsevier202120212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/51902http://dx.doi.org/10.1016/j.aprim.2021.102127reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésAten Primaria. 2021;53(9):102127© 2021 The Author(s). Published by Elsevier España, S.L.U. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/519022026-06-12T07:21:37Z
dc.title.none.fl_str_mv Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
Test rápidos de antígenos para la detección del SARS-CoV-2: Revisión narrativa
title Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
spellingShingle Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
Aguilar-Shea, Antonio L.
Antigen test
COVID-19
Centró de atención médica
Diagnosis
Diagnóstico
Point-of-care
Rapid
Rápido
SARS-CoV-2
Test de antígenos
title_short Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
title_full Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
title_fullStr Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
title_full_unstemmed Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
title_sort Rapid antigen tests for the detection of SARS-CoV-2: A narrative review
dc.creator.none.fl_str_mv Aguilar-Shea, Antonio L.
Vera-García, Mar
Güerri Fernández, Roberto
author Aguilar-Shea, Antonio L.
author_facet Aguilar-Shea, Antonio L.
Vera-García, Mar
Güerri Fernández, Roberto
author_role author
author2 Vera-García, Mar
Güerri Fernández, Roberto
author2_role author
author
dc.subject.none.fl_str_mv Antigen test
COVID-19
Centró de atención médica
Diagnosis
Diagnóstico
Point-of-care
Rapid
Rápido
SARS-CoV-2
Test de antígenos
topic Antigen test
COVID-19
Centró de atención médica
Diagnosis
Diagnóstico
Point-of-care
Rapid
Rápido
SARS-CoV-2
Test de antígenos
description The rapid identificationand isolation of COVID-19 patients has become the cornerstone for the control of the recent outbreak. Real-time quantitative polymerase chain reaction is routinely used to confirm COVID-19 diagnosis and is considered the gold standard due to high sensitivity and specificity. Nevertheless, it usually takes several days and a relatively higher cost. Antigen tests based have emerged to cope with such disadvantages, by offering rapid results, an easy-to-use procedure, and low costs. The objective of the narrative review was to provide up-to-date data about CE-marked rapid antigen tests (RATs) for COVID-19. Given their large number, the study only focused on representative and widely used in Spain (Standard Q, Nadal, Panbio, CerTest, and Wondfo). RATs have become a very useful and validated tool for controlling the spread of COVID-19 allowing the rapid identification of active infection and isolation of positive patients. The present revision of the literature has demonstrated that sensitivity and specificity of all available RATs in Spain are high and accomplish European regulations and WHO recommendations.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/51902
http://dx.doi.org/10.1016/j.aprim.2021.102127
url http://hdl.handle.net/10230/51902
http://dx.doi.org/10.1016/j.aprim.2021.102127
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Aten Primaria. 2021;53(9):102127
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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